Question 1

A 5-year-old male is diagnosed with leukemia.Which of the following symptoms would the nurse expect? (select all that apply)

Accepted Answer

A)  Fatigue 
B)  Jaundice 
C)  Pallor 
D)  Petechiae 
E)  Fever 
A)  Fatigue 
B)  Jaundice 
C)  Pallor 
D)  Petechiae 
E)  Fever A, C, D, E

Question 2

A 12-month-old toddler weighing 18 pounds is brought to the clinic because of weakness, slow physical growth, and developmental delays.His mother reports that the only food he will consume is cow's milk.The symptoms support a diagnosis of which form of anemia?

Accepted Answer

A)  Pernicious 
B)  Iron deficiency 
C)  Aplastic 
D)  Hemolytic 
A)  Pernicious 
B)  Iron deficiency 
C)  Aplastic 
D)  Hemolytic B

Question 3

A 6-year-old male presents with fatigue, jaundice, and irritability.A blood smear shows the presence of sickled cells.Erythropoiesis is compromised in this child; which crisis should the nurse monitor the patient for?

Accepted Answer

A)  Vaso-occlusive crisis 
B)  Sequestration crisis 
C)  Aplastic crisis 
D)  Hyperhemolytic crisis 
A)  Vaso-occlusive crisis 
B)  Sequestration crisis 
C)  Aplastic crisis 
D)  Hyperhemolytic crisis C

Question 4

Which mother-fetus combination is at most risk for a maternal-fetal blood incompatibility?

Accepted Answer

A)  Mother is Rh-positive, and fetus is Rh-negative. 
B)  Mother is Rh-negative, and fetus is Rh-positive. 
C)  Mother has type A blood, and fetus has type O blood. 
D)  Mother has type AB blood, and fetus has type B blood. 
A)  Mother is Rh-positive, and fetus is Rh-negative. 
B)  Mother is Rh-negative, and fetus is Rh-positive. 
C)  Mother has type A blood, and fetus has type O blood. 
D)  Mother has type AB blood, and fetus has type B blood.

Question 5

By what other name is the clotting factor IX disorder, hemophilia B known as?

Accepted Answer

A)  Classic hemophilia 
B)  Christmas disease 
C)  Thalassemia 
D)  von Willebrand disease 
A)  Classic hemophilia 
B)  Christmas disease 
C)  Thalassemia 
D)  von Willebrand disease

Question 6

What is a priority assessment for Hodgkin lymphoma in children?

Accepted Answer

A)  Painless adenopathy in cervical nodes 
B)  Significant bruising 
C)  Weight gain 
D)  Petechiae 
A)  Painless adenopathy in cervical nodes 
B)  Significant bruising 
C)  Weight gain 
D)  Petechiae

Question 7

A 1-year-old female is diagnosed with anemia secondary to insufficient erythropoiesis.The most likely cause is:

Accepted Answer

A)  genetic factors. 
B)  an iron deficiency. 
C)  a hemoglobin abnormality. 
D)  an erythrocyte structural abnormality. 
A)  genetic factors. 
B)  an iron deficiency. 
C)  a hemoglobin abnormality. 
D)  an erythrocyte structural abnormality.

Question 8

If an infant has hydrops fetalis, which type of thalassemia does the nurse suspect?

Accepted Answer

A)  Beta minor 
B)  Beta major 
C)  Alpha minor 
D)  Alpha major 
A)  Beta minor 
B)  Beta major 
C)  Alpha minor 
D)  Alpha major

Question 9

A 5-year-old male is diagnosed with immune thrombocytic purpura (ITP).What is the most common cause of this condition?

Accepted Answer

A)  Normal postnatal platelet lysis 
B)  Virally induced antibody destruction of platelets 
C)  An allergic reaction to vaccinations 
D)  Maternal antibodies that target platelets in the neonate 
A)  Normal postnatal platelet lysis 
B)  Virally induced antibody destruction of platelets 
C)  An allergic reaction to vaccinations 
D)  Maternal antibodies that target platelets in the neonate

Question 10

Sickled cells will be removed from circulation mostly by the:

Accepted Answer

A)  liver. 
B)  pancreas. 
C)  kidney. 
D)  spleen. 
A)  liver. 
B)  pancreas. 
C)  kidney. 
D)  spleen.

Question 11

Which of the following clusters of symptoms would lead the nurse to suspect a child has immune thrombocytopenic purpura (ITP)?

Accepted Answer

A)  Multiple infections; bruising; abnormal bone marrow aspiration 
B)  Lower extremity that is warm to touch, edematous, and painful 
C)  Spontaneous nosebleeds, bruising, and petechiae 
D)  Increased platelet count; recent-onset venous thrombosis 
A)  Multiple infections; bruising; abnormal bone marrow aspiration 
B)  Lower extremity that is warm to touch, edematous, and painful 
C)  Spontaneous nosebleeds, bruising, and petechiae 
D)  Increased platelet count; recent-onset venous thrombosis

Question 12

In the United States, which group of people should be assessed first for sickle cell disease?

Accepted Answer

A)  Asians 
B)  Blacks 
C)  Hispanics 
D)  Whites 
A)  Asians 
B)  Blacks 
C)  Hispanics 
D)  Whites

Question 13

The alpha and beta thalassemias are inherited in an _____ fashion.

Accepted Answer

A)  autosomal recessive 
B)  autosomal dominant 
C)  X-linked recessive 
D)  X-linked dominant 
A)  autosomal recessive 
B)  autosomal dominant 
C)  X-linked recessive 
D)  X-linked dominant

Question 14

Which of the following amino acids is present in Hb S and not present in normal Hb?

Accepted Answer

A)  Valine 
B)  Glutamic acid 
C)  Proline 
D)  Histidine 
A)  Valine 
B)  Glutamic acid 
C)  Proline 
D)  Histidine

Question 15

A 2-year-old male presented with growth and maturation retardation and splenomegaly.He died shortly after arriving at the ER.Autopsy revealed thalassemia secondary to defective:

Accepted Answer

A)  erythrocyte membranes. 
B)  iron metabolism. 
C)  stem cell formation. 
D)  hemoglobin synthesis. 
A)  erythrocyte membranes. 
B)  iron metabolism. 
C)  stem cell formation. 
D)  hemoglobin synthesis.

Question 16

Which major symptom indicates to the nurse that patient diagnosed with sickle cell anemia is experiencing a vasoocclusive crisis?

Accepted Answer

A)  Peripheral edema 
B)  Pain 
C)  Petechiae 
D)  An enlarged spleen 
A)  Peripheral edema 
B)  Pain 
C)  Petechiae 
D)  An enlarged spleen

Question 17

What is the most likely cause of death associated with sickle cell disease?

Accepted Answer

A)  Decreased hemoglobin 
B)  Infection 
C)  An obstructive crisis 
D)  A hyperhemolytic crisis 
A)  Decreased hemoglobin 
B)  Infection 
C)  An obstructive crisis 
D)  A hyperhemolytic crisis

Question 18

A 16-month-old female presents with tachycardia, pallor, anorexia, and systolic murmur.The nurse is checking the lab results, and the hemoglobin determination indicates a level below _____ grams per deciliter.

Accepted Answer

A)  5 
B)  7 
C)  10 
D)  14 
A)  5 
B)  7 
C)  10 
D)  14

Question 19

Which type of sickle cell crisis occurs only in young children?

Accepted Answer

A)  Hyperhemolytic crisis 
B)  Vaso-occlusive crisis 
C)  Aplastic crisis 
D)  Sequestration crisis 
A)  Hyperhemolytic crisis 
B)  Vaso-occlusive crisis 
C)  Aplastic crisis 
D)  Sequestration crisis

Question 20

What is the most serious complication of immune thrombocytopenic purpura (ITP)?

Accepted Answer

A)  Respiratory infection 
B)  Asymmetric bruising 
C)  Intracranial bleeding 
D)  Immunosuppression 
A)  Respiratory infection 
B)  Asymmetric bruising 
C)  Intracranial bleeding 
D)  Immunosuppression

Exam 22: Alterations of Hematologic Function in Children

A 5-year-old male is diagnosed with leukemia.Which of the following symptoms would the nurse expect? (select all that apply)

A 12-month-old toddler weighing 18 pounds is brought to the clinic because of weakness, slow physical growth, and developmental delays.His mother reports that the only food he will consume is cow's milk.The symptoms support a diagnosis of which form of anemia?

A 6-year-old male presents with fatigue, jaundice, and irritability.A blood smear shows the presence of sickled cells.Erythropoiesis is compromised in this child; which crisis should the nurse monitor the patient for?

Which mother-fetus combination is at most risk for a maternal-fetal blood incompatibility?

By what other name is the clotting factor IX disorder, hemophilia B known as?

What is a priority assessment for Hodgkin lymphoma in children?

A 1-year-old female is diagnosed with anemia secondary to insufficient erythropoiesis.The most likely cause is:

If an infant has hydrops fetalis, which type of thalassemia does the nurse suspect?

A 5-year-old male is diagnosed with immune thrombocytic purpura (ITP).What is the most common cause of this condition?

Sickled cells will be removed from circulation mostly by the:

Which of the following clusters of symptoms would lead the nurse to suspect a child has immune thrombocytopenic purpura (ITP)?

In the United States, which group of people should be assessed first for sickle cell disease?

The alpha and beta thalassemias are inherited in an _____ fashion.

Which of the following amino acids is present in Hb S and not present in normal Hb?

A 2-year-old male presented with growth and maturation retardation and splenomegaly.He died shortly after arriving at the ER.Autopsy revealed thalassemia secondary to defective:

Which major symptom indicates to the nurse that patient diagnosed with sickle cell anemia is experiencing a vasoocclusive crisis?

What is the most likely cause of death associated with sickle cell disease?

A 16-month-old female presents with tachycardia, pallor, anorexia, and systolic murmur.The nurse is checking the lab results, and the hemoglobin determination indicates a level below _____ grams per deciliter.

Which type of sickle cell crisis occurs only in young children?

What is the most serious complication of immune thrombocytopenic purpura (ITP)?

Cellular Biology

Genes and Genetic Diseases

Epigenetics and Disease

Altered Cellular and Tissue Biology

Fluids and Electrolytes, Acids and Bases

Innate Immunity: Inflammation and Wound Healing

Adaptive Immunity

Infection and Defects in Mechanisms of Defense

Stress and Disease

Biology, Clinical Manifestations, and Treatment of Cancer

Cancer Epidemiology

Cancer in Children

Structure and Function of the Neurologic System

Pain, Temperature, Sleep, and Sensory Function

Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function

Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction

Alterations of Neurologic Function in Children

Mechanisms of Hormonal Regulation

Alterations of Hormonal Regulation

Structure and Function of the Hematologic System

Alterations of Hematologic Function

Structure and Function of the Cardiovascular and Lymphatic Systems

Alterations of Cardiovascular Function

Alterations of Cardiovascular Function in Children

Structure and Function of the Pulmonary System

Alterations of Pulmonary Function

Alterations of Pulmonary Function in Children

Structure and Function of the Renal and Urologic Systems

Alterations of Renal and Urinary Tract Function

Alterations of Renal and Urinary Tract Function in Children

Structure and Function of the Reproductive Systems

Alterations of the Female Reproductive System

Alterations of the Male Reproductive System

Structure and Function of the Digestive System

Alterations of Digestive Function

Alterations of Digestive Function in Children

Structure and Function of the Musculoskeletal System

Alterations of Musculoskeletal Function

Alterations of Musculoskeletal Function in Children

Structure, Function, and Disorders of the Integument

Alterations of the Integument in Children

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