Exam 11: DNA Replication and Recombination

DNA strand replication begins with an RNA primer.

In ligase-deficient strains of E. coli, DNA and chromosomal replication are unaltered because ligase is not involved in DNA replication.

Describe the DNA base sequence arrangement at the end of the Tetrahymena chromosome and the resolution of DNA replication at the end of a linear DNA strand.

The complex of proteins that is involved in the replication of DNA is called a(n) ________.

Each of the following terms refers to the replication of chromosomes. Describe the role (relationship) of each in (to) chromosome replication. (a) Okazaki fragment (b) Lagging strand (c) Bidirectional

DNA replicates conservatively, which means that one of the two daughter double helices is "old" and the other is "new."

Describe a somewhat extraordinary finding related to the Tetrahymena telomerase enzyme.

Structures located at the ends of eukaryotic chromosomes are called ________.

G-quartets are G-rich single-stranded tails that loop back on themselves forming G-G double stranded sections. Such looping is involved in aligning chromosomes for homologous recombination.

Meselson and Stahl determined that DNA replication in E coli is semiconservative. What additive did they initially supply to the medium in order to distinguish "new" from "old" DNA?