Exam 9: DNA Structure and Analysis

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What is meant by the term antiparallel?

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The two chains in a double -stranded nucleic acid are connected in opposite directions in terms of 5' -3' orientation.

What are the two major components of the Tobacco Mosaic Virus?

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Name the pyrimidines and the purines in DNA.

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pyrimidines: cytosine and thymine; purines: adenine and guanine

The basic structure of a nucleotide includes _.

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List three forms of DNA.

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Experiments conducted in the 1920s by Frederick Griffith involving the bacterium Diplococcus pneumoniae demonstrated that a substance from one bacterial strain could genetically transform other bacterial strains. What was the name of the substance capable of such transformation, and who finally determined its identity?

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(a) Assume that A + T/G + C equals 0.5 in one strand of DNA. What is the ratio of these bases in the complementary strand? (b) If A + G/T + C equals 0.5 in one strand, what is the ratio of these bases in the complementary strand?

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In an analysis of the nucleotide composition of double -stranded DNA to see which bases are equivalent in concentration, which of the following would be true?

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The strongest direct evidence that DNA is the genetic material comes from which contemporary methodology?

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The base content of a sample of DNA is as follows: A = 31%, G = 31%, T = 19%, C = 19%. What conclusion can be drawn from this information?

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What was the Avery et al.'s (1944) contribution to the understanding of molecular biology?

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Hershey and Chase used labeled DNA and protein to determine that DNA is the genetic material in bacteria.

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The classic Hershey and Chase (1952) experiment that offered evidence in support of DNA being the genetic material in bacteriophages made use of which of the following labeled component(s)?

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Avery et al. (1944) determined that DNA is the genetic material in T2 bacteriophage.

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Beatrice Mintz and others microinjected DNA into a fertilized mouse egg that after reaching maturity could be transmitted to the mouse's offspring. What is the general term used to describe an organism that incorporates foreign DNA?

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Is the accompanying figure DNA or RNA? Is the circle closer to the 5' or 3' end? Is the accompanying figure DNA or RNA? Is the circle closer to the 5' or 3' end?

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Regarding the structure of DNA, the covalently arranged combination of a deoxyribose and a nitrogenous base would be called a(n) _.

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Provide an overview of the structure of Z -DNA.

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What does it mean to say that double -stranded nucleic acids are antiparallel?

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In the classic experiment conducted by Hershey and Chase, why was the pellet radioactive in the centrifuge tube that contained bacteria with viruses?

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