Question 1

A child with a history of recent strep throat infection develops glomerulonephritis.This is most likely a type _____ hypersensitivity reaction.

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
A)  I 
B)  II 
C)  III 
D)  IV C

Question 2

Severe combined immunodeficiency (SCID)syndrome is an example of a(n)

Accepted Answer

A)  deficient immune response. 
B)  excessive immune response. 
C)  primary acquired immunodeficiency. 
D)  hypersensitivity reaction. 
A)  deficient immune response. 
B)  excessive immune response. 
C)  primary acquired immunodeficiency. 
D)  hypersensitivity reaction. A

Question 3

Transfusion reactions involve RBC destruction caused by

Accepted Answer

A)  donor antigens. 
B)  recipient antibodies. 
C)  donor T cells. 
D)  recipient T cells. 
A)  donor antigens. 
B)  recipient antibodies. 
C)  donor T cells. 
D)  recipient T cells. B

Question 4

The hypersensitivity reaction that does not involve antibody production is type

Accepted Answer

A)  I. 
B)  II. 
C)  III. 
D)  IV. 
A)  I. 
B)  II. 
C)  III. 
D)  IV.

Question 5

The effects of histamine release include

Accepted Answer

A)  vasoconstriction. 
B)  bronchodilation. 
C)  increased vascular permeability. 
D)  decreased gut permeability. 
A)  vasoconstriction. 
B)  bronchodilation. 
C)  increased vascular permeability. 
D)  decreased gut permeability.

Question 6

Which disorder is considered a primary immunodeficiency disease?

Accepted Answer

A)  HIV/AIDS 
B)  Malnutrition immunodeficiency 
C)  Cancer immunodeficiency 
D)  Radiation immunodeficiency 
A)  HIV/AIDS 
B)  Malnutrition immunodeficiency 
C)  Cancer immunodeficiency 
D)  Radiation immunodeficiency

Question 7

RhoGAM (an Rh antibody)would be appropriate in an Rh-_____ woman with an _____ Rh-_____ antibody titer carrying an Rh-_____ fetus.

Accepted Answer

A)  negative; positive; positive 
B)  positive; negative; negative 
C)  negative; negative; positive 
D)  negative; negative; negative 
A)  negative; positive; positive 
B)  positive; negative; negative 
C)  negative; negative; positive 
D)  negative; negative; negative

Question 8

An important mediator of a type I hypersensitivity reaction is

Accepted Answer

A)  complement. 
B)  antigen-antibody immune complexes. 
C)  T cells. 
D)  histamine. 
A)  complement. 
B)  antigen-antibody immune complexes. 
C)  T cells. 
D)  histamine.

Question 9

Seasonal allergic rhinitis is most involved in type ____ hypersensitivity reactions.

Accepted Answer

I
Seasonal allergic

Question 10

Anaphylaxis may occur in certain hypersensitivity reactions, including type

Accepted Answer

A)  I. 
B)  II. 
C)  III. 
D)  IV. 
A)  I. 
B)  II. 
C)  III. 
D)  IV.

Question 11

Patients with immunodeficiency disorders are usually first identified because they

Accepted Answer

A)  run high fevers. 
B)  have unusually high WBC counts. 
C)  develop brain infections. 
D)  develop recurrent infections. 
A)  run high fevers. 
B)  have unusually high WBC counts. 
C)  develop brain infections. 
D)  develop recurrent infections.

Question 12

Secondary immune deficiency problems may be caused by

Accepted Answer

A)  surgery. 
B)  high blood sugar. 
C)  corticosteroids. 
D)  genetic disorders. 
E)  low protein level. 
A)  surgery. 
B)  high blood sugar. 
C)  corticosteroids. 
D)  genetic disorders. 
E)  low protein level.

Question 13

Autoimmune diseases result from

Accepted Answer

A)  overactive immune function. 
B)  increase in self-tolerance. 
C)  failure of the immune system to differentiate self and nonself molecules. 
D)  communicable infections. 
A)  overactive immune function. 
B)  increase in self-tolerance. 
C)  failure of the immune system to differentiate self and nonself molecules. 
D)  communicable infections.

Question 14

The most common primary immune deficiency that affects only B cells is

Accepted Answer

A)  DiGeorge. 
B)  Bruton agammaglobulinemia. 
C)  Wiskott-Aldrich. 
D)  selective IgA. 
A)  DiGeorge. 
B)  Bruton agammaglobulinemia. 
C)  Wiskott-Aldrich. 
D)  selective IgA.

Question 15

A primary effector cell of the type I hypersensitivity response is

Accepted Answer

A)  monocytes. 
B)  mast cells. 
C)  neutrophils. 
D)  cytotoxic cells. 
A)  monocytes. 
B)  mast cells. 
C)  neutrophils. 
D)  cytotoxic cells.

Question 16

Myasthenia gravis is a type II hypersensitivity disorder that involves

Accepted Answer

A)  impaired muscle function. 
B)  symptoms of hyperthyroidism. 
C)  symptoms of arthritis or polyarthralgia. 
D)  symptoms of glomerular disease. 
A)  impaired muscle function. 
B)  symptoms of hyperthyroidism. 
C)  symptoms of arthritis or polyarthralgia. 
D)  symptoms of glomerular disease.

Question 17

Certain autoimmune diseases are associated with the presence of specific proteins on a person's cells.These proteins are called ________ proteins.

Accepted Answer

A)  complement 
B)  antibody receptor 
C)  HLA or MHC 
D)  TCR or BCR 
A)  complement 
B)  antibody receptor 
C)  HLA or MHC 
D)  TCR or BCR

Question 18

Which disorder is associated with a type III hypersensitivity mechanism of injury?

Accepted Answer

A)  Systemic lupus erythematosus 
B)  Graves disease 
C)  Erythroblastosis fetalis 
D)  Seasonal allergic rhinitis 
A)  Systemic lupus erythematosus 
B)  Graves disease 
C)  Erythroblastosis fetalis 
D)  Seasonal allergic rhinitis

Question 19

The principle Ig mediator of type I hypersensitivity reactions is

Accepted Answer

A)  IgA. 
B)  IgG. 
C)  IgM. 
D)  IgE. 
A)  IgA. 
B)  IgG. 
C)  IgM. 
D)  IgE.

Question 20

Dramatic hypotension sometimes accompanies type I hypersensitivity reactions, because

Accepted Answer

A)  massive histamine release from mast cells leads to vasodilation. 
B)  toxins released into the blood interfere with cardiac function. 
C)  anaphylaxis results in large volume losses secondary to sweating. 
D)  hypoxia due to bronchoconstriction impairs cardiac function. 
A)  massive histamine release from mast cells leads to vasodilation. 
B)  toxins released into the blood interfere with cardiac function. 
C)  anaphylaxis results in large volume losses secondary to sweating. 
D)  hypoxia due to bronchoconstriction impairs cardiac function.

Exam 10: Alterations in Immune Function

A child with a history of recent strep throat infection develops glomerulonephritis.This is most likely a type _____ hypersensitivity reaction.

Severe combined immunodeficiency (SCID)syndrome is an example of a(n)

Transfusion reactions involve RBC destruction caused by

The hypersensitivity reaction that does not involve antibody production is type

The effects of histamine release include

Which disorder is considered a primary immunodeficiency disease?

RhoGAM (an Rh antibody)would be appropriate in an Rh-_____ woman with an _____ Rh-_____ antibody titer carrying an Rh-_____ fetus.

An important mediator of a type I hypersensitivity reaction is

Seasonal allergic rhinitis is most involved in type ____ hypersensitivity reactions.

Anaphylaxis may occur in certain hypersensitivity reactions, including type

Patients with immunodeficiency disorders are usually first identified because they

Secondary immune deficiency problems may be caused by

Autoimmune diseases result from

The most common primary immune deficiency that affects only B cells is

A primary effector cell of the type I hypersensitivity response is

Myasthenia gravis is a type II hypersensitivity disorder that involves

Certain autoimmune diseases are associated with the presence of specific proteins on a person's cells.These proteins are called ________ proteins.

Which disorder is associated with a type III hypersensitivity mechanism of injury?

The principle Ig mediator of type I hypersensitivity reactions is

Dramatic hypotension sometimes accompanies type I hypersensitivity reactions, because

Introduction to Pathophysiology

Homeostasis and Adaptive Responses to Stressors

Cell Structure and Function

Cell Injury, Aging, and Death

Genome Structure, Regulation, and Tissue Differentiation

Genetic and Developmental Disorders

Neoplasia

Infectious Processes

Inflammation and Immunity

Malignant Disorders of White Blood Cells

HIV Disease and AIDS

Alterations in Oxygen Transport

Alterations in Hemostasis and Blood Coagulation

Alterations in Blood Flow

Alterations in Blood Pressure

Cardiac Function

Alterations in Cardiac Function

Heart Failure and Dysrhythmias: Common Sequelae of Cardiac Diseases

Shock

Respiratory Function and Alterations in Gas Exchange

Obstructive Pulmonary Disorders

Restrictive Pulmonary Disorders

Fluid and Electrolyte Homeostasis and Imbalances

Acid-Base Homeostasis and Imbalances

Renal Function

Intrarenal Disorders

Acute Kidney Injury and Chronic Kidney Disease

Disorders of the Lower Urinary Tract

Male Genital and Reproductive Function

Alterations in Male Genital and Reproductive Function

Female Genital and Reproductive Function

Alterations in Female Genital and Reproductive Function

Sexually Transmitted Infections

Gastrointestinal Function

Gastrointestinal Disorders

Alterations in Function of the Gallbladder and Exocrine Pancreas

Liver Diseases

Endocrine Physiology and Mechanisms of Hypothalamic-Pituitary Regulation

Disorders of Endocrine Function

Diabetes Mellitus

Alterations in Metabolism and Nutrition

Structure and Function of the Nervous System

Acute Disorders of Brain Function

Chronic Disorders of Neurologic Function

Alterations in Special Sensory Function

Pain

Neurobiology of Psychotic Illnesses

Neurobiology of Nonpsychotic Illnesses

Structure and Function of the Musculoskeletal System

Alterations in Musculoskeletal Function: Trauma, Infection, and Disease

Alterations in Musculoskeletal Function: Rheumatic Disorders

Alterations in the Integumentary System

Burn Injuries

Filters

RhoGAM (an Rh antibody)would be appropriate in an Rh-___ woman with an _ Rh-_ antibody titer carrying an Rh-___ fetus.