Exam 8: RNA Synthesis and Processing

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The genes for the 5S, 5.8S and 28S rRNAs are found in tandem and transcribed as a unit.

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Transcription is _______-dependent _______ synthesis.

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What are the two signals for polyadenylation of mRNA?

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What are the five types of small nuclear RNAs that make up the spliceosome?

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The 5′ end of messenger RNA is modified by

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The regions of the DNA where RNA polymerase binds can be identified by

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Which process both stabilizes and increases the efficiency of translation of an mRNA?

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During transcriptional initiation in eukaryotes, _______ is responsible for phosphorylating RNA polymerase II C-terminal domain (CTD).

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Self-splicing was discovered in studies of the

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Sigma ( σ\sigma ) subunits of bacterial RNA polymerase initiate binding to the DNA and are released from the polymerase at the end of transcription.

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A ribozyme is defined as an enzyme

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Explain why bacterial mRNAs need to be very unstable, usually having half-lives of about 2 to 3 minutes.

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The signal for the addition of a poly-A tail to pre-mRNA is

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Identify two functions of capping and polyadenylation of mRNA.

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The 7-methylguanosine cap on mNRA is required for

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The role of the sigma ( σ\sigma ) factor in prokaryote transcription is to

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What are two reasons why eukaryotic transcription is considered to be more complex than bacterial transcription?

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How was RNA editing first discovered?

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The predominant RNA synthesized by eukaryotic RNA polymerase II is _______.

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Transcription of a bacterial gene is initiated

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