Question 1

The eukaryote Caenorhabditis elegans has been used especially in the study of

Accepted Answer

A)  animal development. 
B)  photosynthesis. 
C)  flagellar movement. 
D)  immunology. 
A)  animal development. 
B)  photosynthesis. 
C)  flagellar movement. 
D)  immunology.

Question 2

Potential protein-coding regions of genomic DNA containing long stretches of nucleotide sequences that can encode polypeptides and contain no stop codons are called

Accepted Answer

A)  introns. 
B)  exons. 
C)  pseudogenes. 
D)  open-reading frames. 
A)  introns. 
B)  exons. 
C)  pseudogenes. 
D)  open-reading frames.

Question 3

Which method uses an antibody that recognizes cellular proteins to investigate protein-protein interactions?

Accepted Answer

A)  Immunoprecipitation 
B)  The yeast two-hybrid system 
C)  Protein array 
D)  Electrophoretic mobility shift assay 
A)  Immunoprecipitation 
B)  The yeast two-hybrid system 
C)  Protein array 
D)  Electrophoretic mobility shift assay

Question 4

The Arabidopsis genome, like many plant genomes, contains more genes than many animals. This is due largely to

Accepted Answer

A)  fewer stop codons. 
B)  larger exons. 
C)  larger introns. 
D)  gene duplication. 
A)  fewer stop codons. 
B)  larger exons. 
C)  larger introns. 
D)  gene duplication.

Question 5

The treat malaria, pharmaceutical company Sanofi developed

Accepted Answer

A)  a genetic toggle switch that induced apoptosis genes in Plasmodium falciparum. 
B)  a method to extract high yields of artemisinin from the sweet wormwood plant. 
C)  a sterile strain of Plasmodium falciparum. 
D)  a new yeast strain that produces artemisinic acid. 
A)  a genetic toggle switch that induced apoptosis genes in Plasmodium falciparum. 
B)  a method to extract high yields of artemisinin from the sweet wormwood plant. 
C)  a sterile strain of Plasmodium falciparum. 
D)  a new yeast strain that produces artemisinic acid.

Question 6

About half of the human genes identified by sequencing can be assigned a function by homology to previously characterized genes, and the other half represent new genes of unknown function.

Accepted Answer

A) True 
 B)False

Question 7

In comparing the genomes of two yeasts, S. pombe and S. cerevisiae, researchers found that S. pombe contains more _______.

Accepted Answer

The answer of In comparing the genomes of two yeasts,...

Question 8

Sequencing the genomes of Caenorhabditis elegans and Drosophila melanogaster led to the discovery of many new genes for

Accepted Answer

A)  enzymes of cell metabolism. 
B)  proteins regulating the cell cycle. 
C)  proteins regulating mitosis. 
D)  proteins regulating animal development. 
A)  enzymes of cell metabolism. 
B)  proteins regulating the cell cycle. 
C)  proteins regulating mitosis. 
D)  proteins regulating animal development.

Question 9

When carrying out immunoprecipitation experiments to investigate protein-protein interactions, why is it important to isolate the proteins under gentle conditions?

Accepted Answer

Protein-protein interactions are due to

Question 10

Stretches of sequenced nucleotides that code for polypeptides are recognized by the

Accepted Answer

A)  presence of a start codon. 
B)  absence of chain-terminating codons. 
C)  presence of closed-reading frames. 
D)  absence of open-reading frames. 
A)  presence of a start codon. 
B)  absence of chain-terminating codons. 
C)  presence of closed-reading frames. 
D)  absence of open-reading frames.

Question 11

Remarkably, approximately _______% of the predicted human proteins are related to proteins in simpler sequenced eukaryotes, including yeast, Drosophila, and C. elegans.

Accepted Answer

40 (accept

Question 12

Surprisingly, after sequencing many different species, what organism stands out as having the largest number of genes?

Accepted Answer

A)  Arabidopsis 
B)  Zebrafish 
C)  Chimpanzee 
D)  Apple 
A)  Arabidopsis 
B)  Zebrafish 
C)  Chimpanzee 
D)  Apple

Question 13

In 2010, scientists developed a series of overlapping oligonucleotides that extended a full 1.08 million base pairs and used it to develop the first complete organism using a synthetic genome. The newly created cells had normal growth and morphology. In addition to the synthetic genome, why did the investigators also include a gene that confers resistance to tetracycline?

Accepted Answer

A)  By including an exogenous gene, they could confirm propagation of the genome by PCR. 
B)  The tetracycline resistance gene increases the genomic stability of genomes in prokaryotes. 
C)  The tetracycline resistance gene destabilizes the genome of the host DNA allowing the novel synthetic genome to survive. 
D)  The tetracycline resistance gene allows the selection of only the cells that are resistant to tetracycline and thus cells that survive selection carry the novel synthetic genome. 
A)  By including an exogenous gene, they could confirm propagation of the genome by PCR. 
B)  The tetracycline resistance gene increases the genomic stability of genomes in prokaryotes. 
C)  The tetracycline resistance gene destabilizes the genome of the host DNA allowing the novel synthetic genome to survive. 
D)  The tetracycline resistance gene allows the selection of only the cells that are resistant to tetracycline and thus cells that survive selection carry the novel synthetic genome.

Question 14

A long DNA sequence with no stop codons is a(n) _______.

Accepted Answer

The answer of A long DNA sequence with no stop...

Question 15

Based on major technological innovations since the late 1990s, the relatively new field of bioinformatics has been growing significantly. Describe the need for and the uses of bioinformatics.

Accepted Answer

Recent advances in sequencing technology

Question 16

The use of antibodies to determine protein-protein interactions is known as _______.

Accepted Answer

The answer of The use of antibodies to determine protein-protein...

Question 17

The simplest eukaryotic genome is found in

Accepted Answer

A)  Saccharomyces cerevisiae. 
B)  Caenorhabditis elegans. 
C)  Drosophila melanogaster. 
D)  Arabidopsis thaliana. 
A)  Saccharomyces cerevisiae. 
B)  Caenorhabditis elegans. 
C)  Drosophila melanogaster. 
D)  Arabidopsis thaliana.

Question 18

Which method for investigating protein-protein interactions uses gene expression as the detection component?

Accepted Answer

A)  Yeast two-hybrid 
B)  Immunoprecipitation 
C)  Mass spectrometry 
D)  Tandem mass spectrometry 
A)  Yeast two-hybrid 
B)  Immunoprecipitation 
C)  Mass spectrometry 
D)  Tandem mass spectrometry

Question 19

Mass spectrometers are used to

Accepted Answer

A)  transport a molecule against its concentration gradient. 
B)  couple the energy of ATP hydrolysis to a configurational change. 
C)  transport H+ across a membrane against a pH gradient. 
D)  identify proteins by mass/ratio peptide analysis as part of proteomic procedures. 
A)  transport a molecule against its concentration gradient. 
B)  couple the energy of ATP hydrolysis to a configurational change. 
C)  transport H+ across a membrane against a pH gradient. 
D)  identify proteins by mass/ratio peptide analysis as part of proteomic procedures.

Question 20

In 1995, the first complete genome of _______ was sequenced by Dr. Craig Venter.

Accepted Answer

A)  Escherichia coli 
B)  Saccharomyces cerevisiae 
C)  Haemophilus influenzae 
D)  Caenorhabditis elegans 
A)  Escherichia coli 
B)  Saccharomyces cerevisiae 
C)  Haemophilus influenzae 
D)  Caenorhabditis elegans

The eukaryote Caenorhabditis elegans has been used especially in the study of

Potential protein-coding regions of genomic DNA containing long stretches of nucleotide sequences that can encode polypeptides and contain no stop codons are called

Which method uses an antibody that recognizes cellular proteins to investigate protein-protein interactions?

The Arabidopsis genome, like many plant genomes, contains more genes than many animals. This is due largely to

The treat malaria, pharmaceutical company Sanofi developed

About half of the human genes identified by sequencing can be assigned a function by homology to previously characterized genes, and the other half represent new genes of unknown function.

In comparing the genomes of two yeasts, S. pombe and S. cerevisiae, researchers found that S. pombe contains more _______.

Sequencing the genomes of Caenorhabditis elegans and Drosophila melanogaster led to the discovery of many new genes for

When carrying out immunoprecipitation experiments to investigate protein-protein interactions, why is it important to isolate the proteins under gentle conditions?

Stretches of sequenced nucleotides that code for polypeptides are recognized by the

Remarkably, approximately _______% of the predicted human proteins are related to proteins in simpler sequenced eukaryotes, including yeast, Drosophila, and C. elegans.

Surprisingly, after sequencing many different species, what organism stands out as having the largest number of genes?

A long DNA sequence with no stop codons is a(n) _______.

Based on major technological innovations since the late 1990s, the relatively new field of bioinformatics has been growing significantly. Describe the need for and the uses of bioinformatics.

The use of antibodies to determine protein-protein interactions is known as _______.

The simplest eukaryotic genome is found in

Which method for investigating protein-protein interactions uses gene expression as the detection component?

Mass spectrometers are used to

In 1995, the first complete genome of _______ was sequenced by Dr. Craig Venter.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

Exam 5: Genomics, Proteomics, and Systems Biology

The eukaryote Caenorhabditis elegans has been used especially in the study of

Potential protein-coding regions of genomic DNA containing long stretches of nucleotide sequences that can encode polypeptides and contain no stop codons are called

Which method uses an antibody that recognizes cellular proteins to investigate protein-protein interactions?

The Arabidopsis genome, like many plant genomes, contains more genes than many animals. This is due largely to

The treat malaria, pharmaceutical company Sanofi developed

About half of the human genes identified by sequencing can be assigned a function by homology to previously characterized genes, and the other half represent new genes of unknown function.

In comparing the genomes of two yeasts, S. pombe and S. cerevisiae, researchers found that S. pombe contains more _______.

Sequencing the genomes of Caenorhabditis elegans and Drosophila melanogaster led to the discovery of many new genes for

When carrying out immunoprecipitation experiments to investigate protein-protein interactions, why is it important to isolate the proteins under gentle conditions?

Stretches of sequenced nucleotides that code for polypeptides are recognized by the

Remarkably, approximately _______% of the predicted human proteins are related to proteins in simpler sequenced eukaryotes, including yeast, Drosophila, and C. elegans.

Surprisingly, after sequencing many different species, what organism stands out as having the largest number of genes?

A long DNA sequence with no stop codons is a(n) _______.

Based on major technological innovations since the late 1990s, the relatively new field of bioinformatics has been growing significantly. Describe the need for and the uses of bioinformatics.

The use of antibodies to determine protein-protein interactions is known as _______.

The simplest eukaryotic genome is found in

Which method for investigating protein-protein interactions uses gene expression as the detection component?

Mass spectrometers are used to

In 1995, the first complete genome of _______ was sequenced by Dr. Craig Venter.

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

RNA Synthesis and Processing

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters