Exam 13: Signal Transduction Mechanisms: Ielectrical and Synaptic Signaling in Neurons

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For treatment of ADHD (attention deficit hyperactivity disorder),tricyclic antidepressants are often prescribed.These drugs act by affecting the reuptake of neurotransmitters.What effects does this have on the postsynaptic neuron? (Assume an excitatory neurotransmitter.)

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Question 1

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Tricyclic antidepressants,such as imipramine hydrochloride,work by allowing the excitatory neurotransmitters to remain in the synaptic cleft for longer periods of time.Because the neurotransmitters are present for longer periods of time,they increase the number of successive action potentials generated by the postsynaptic neuron.

As a result of the way nerve impulses are propagated,they are unidirectional.Which of the following does not contribute to this phenomenon?

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Which neurotransmitter is not an amino acid derivative?

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Question 3

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Refer to the graph above.If the myelin fibers were stripped from this membrane,you would expect the action potential cycle to go

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Question 4

An electrical current of 1 A is approximately 6 x 10¹⁸ electrical charges per second; how many ions pass through the channel when it is open?

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Question 5

A particular neuron does not release neurotransmitters into the synaptic cleft.Further investigation shows that this cell does not respond to calcium ions that are necessary for t- and v-SNARE complex interaction.The most likely problem is associated with the function of

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Question 6

Based on the graph above,the threshold voltage appears to be approximately

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Question 7

Ions of initiate the release of a neurotransmitter,such as acetylcholine,via into the synaptic cleft.

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Question 8

Exposure to sarin,a potent nerve gas,results in muscle paralysis.Therefore,sarin must interfere with which neurotransmitter?

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Question 9

All of the following are glial cells except

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Question 10

You stimulate a neuron response by adding a given amount of excitatory neurotransmitter mixed with a 6x higher concentration of an inhibitory neurotransmitter to the synaptic cleft.You expect that

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Question 11

The stimulation of a neuron by a signal may ultimately stimulate

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Question 12

Describe the docking and fusion of vesicles with the cell membrane.How do tetanus toxin and botulinum toxin work to interfere with this process?

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Question 13

Which equation best describes the relationship between ion gradient and equilibrium potential for that ion?

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Question 14

The equation accounts for the movement of a single ion type,while the equation takes into account the movement of multiple ions on membrane potential.

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Question 15

The portion of the nervous system that is associated with the control of involuntary activities is the

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Question 16

Catecholamines are synthesized by the

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Question 17

The phase at the end of an action potential when the membrane potential becomes more negative than it is at rest is the ________ phase.

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Question 18

An ________ of a nerve cell is the temporary depolarization and repolarization of the cell membrane.

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Question 19

The sweetener aspartame is a known excitotoxin.With regard to nerve cells,ingestion of this substance results in chronic nerve stimulation.With your knowledge of action potentials,this toxin must

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Question 20

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Exam 13: Signal Transduction Mechanisms: Ielectrical and Synaptic Signaling in Neurons

For treatment of ADHD (attention deficit hyperactivity disorder),tricyclic antidepressants are often prescribed.These drugs act by affecting the reuptake of neurotransmitters.What effects does this have on the postsynaptic neuron? (Assume an excitatory neurotransmitter.)

As a result of the way nerve impulses are propagated,they are unidirectional.Which of the following does not contribute to this phenomenon?

Which neurotransmitter is not an amino acid derivative?

Refer to the graph above.If the myelin fibers were stripped from this membrane,you would expect the action potential cycle to go

An electrical current of 1 A is approximately 6 x 10¹⁸ electrical charges per second; how many ions pass through the channel when it is open?

A particular neuron does not release neurotransmitters into the synaptic cleft.Further investigation shows that this cell does not respond to calcium ions that are necessary for t- and v-SNARE complex interaction.The most likely problem is associated with the function of

Based on the graph above,the threshold voltage appears to be approximately

Ions of ________ initiate the release of a neurotransmitter,such as acetylcholine,via ________ into the synaptic cleft.

Exposure to sarin,a potent nerve gas,results in muscle paralysis.Therefore,sarin must interfere with which neurotransmitter?

All of the following are glial cells except

You stimulate a neuron response by adding a given amount of excitatory neurotransmitter mixed with a 6x higher concentration of an inhibitory neurotransmitter to the synaptic cleft.You expect that

The stimulation of a neuron by a signal may ultimately stimulate

Describe the docking and fusion of vesicles with the cell membrane.How do tetanus toxin and botulinum toxin work to interfere with this process?

Which equation best describes the relationship between ion gradient and equilibrium potential for that ion?

The ________ equation accounts for the movement of a single ion type,while the ________ equation takes into account the movement of multiple ions on membrane potential.

The portion of the nervous system that is associated with the control of involuntary activities is the

Catecholamines are synthesized by the

The phase at the end of an action potential when the membrane potential becomes more negative than it is at rest is the ________ phase.

An ________ of a nerve cell is the temporary depolarization and repolarization of the cell membrane.

The sweetener aspartame is a known excitotoxin.With regard to nerve cells,ingestion of this substance results in chronic nerve stimulation.With your knowledge of action potentials,this toxin must

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Ions of initiate the release of a neurotransmitter,such as acetylcholine,via into the synaptic cleft.

The equation accounts for the movement of a single ion type,while the equation takes into account the movement of multiple ions on membrane potential.