Question 1

Base sequence variations between individuals that result from point mutations are called

Accepted Answer

A) polymorphs. 
B) small nuclear polymorphisms. 
C) deletions. 
D) single nucleotide polymorphisms. 
E) restriction fragment length polymorphisms. 
A) polymorphs. 
B) small nuclear polymorphisms. 
C) deletions. 
D) single nucleotide polymorphisms. 
E) restriction fragment length polymorphisms. D

Question 2

The ________ is the entire set of proteins expressed by a genome.

Accepted Answer

proteome.

Question 3

A recently isolated bacterial strain has been given to you for general characterization of the genome.You begin by isolating the DNA and subjecting it to thermal denaturation.You use Escherichia coli DNA as a reference (A + T = G +C).
  Figure 18.1
Based on the information in the graph, you can determine that the DNA has a high

Accepted Answer

A) G-C content with respect to E. coli. 
B) pyrimidine content with respect to E. coli. 
C) A-T content with respect to E. coli. 
D) purine content, with respect to E. coli. 
E) none of the above 
A) G-C content with respect to E. coli. 
B) pyrimidine content with respect to E. coli. 
C) A-T content with respect to E. coli. 
D) purine content, with respect to E. coli. 
E) none of the above A

Question 4

An example of a purine is

Accepted Answer

A) thymine. 
B) guanine. 
C) acridine. 
D) cytosine. 
E) uracil. 
A) thymine. 
B) guanine. 
C) acridine. 
D) cytosine. 
E) uracil.

Question 5

With regard to DNA packaging,prokaryotic chromosomes

Accepted Answer

A) are devoid of histone or histone-like proteins. 
B) are, in general, positively supercoiled. 
C) have no higher-level structure, such as looped domains. 
D) use RNA to contribute to chromosomal packaging. 
E) none of the above 
A) are devoid of histone or histone-like proteins. 
B) are, in general, positively supercoiled. 
C) have no higher-level structure, such as looped domains. 
D) use RNA to contribute to chromosomal packaging. 
E) none of the above

Question 6

Circular DNA molecules found in nature (such as bacterial,viral,or mitochondrial DNA)are

Accepted Answer

A) positively supercoiled. 
B) negatively supercoiled. 
C) not supercoiled, due to their small size. 
D) always oriented in a triple helix to conserve space. 
E) always in the relaxed state. 
A) positively supercoiled. 
B) negatively supercoiled. 
C) not supercoiled, due to their small size. 
D) always oriented in a triple helix to conserve space. 
E) always in the relaxed state.

Question 7

Two common transposable elements associated with interspersed repeated DNA are ________ and ________.

Accepted Answer

The answer of Two common transposable elements associated with interspersed...

Question 8

Restriction enzymes typically recognize

Accepted Answer

A) sequences in threefold symmetry. 
B) single-stranded DNA only. 
C) specific palindromic sequences. 
D) several nucleotide sequences simultaneously. 
E) all of the above 
A) sequences in threefold symmetry. 
B) single-stranded DNA only. 
C) specific palindromic sequences. 
D) several nucleotide sequences simultaneously. 
E) all of the above

Question 9

Because of its antiparallel nature,DNA is often referred to as a ________.

Accepted Answer

The answer of Because of its antiparallel nature,DNA is often...

Question 10

Which of the following are components of Chargaff's rules of bases?

Accepted Answer

A) purines = pyrimidines 
B) C + T = A + G 
C) A + T = G + C 
D) G = C 
E) all of the above 
A) purines = pyrimidines 
B) C + T = A + G 
C) A + T = G + C 
D) G = C 
E) all of the above

Question 11

A husband and wife are in the process of getting a divorce.During child-support hearings,the husband states that he should not pay child support as he feels that the child was actually fathered by one of the woman's various lovers.DNA restriction analysis was performed,with the results illustrated in the diagram below.
   
Figure 18.3
The DNA of the husband in this case can be found in lane 3, whereas that of the suspected father is in lane 4. Based on this information,

Accepted Answer

A) the husband is definitely the child's father. 
B) the husband is definitely not the child's father. 
C) either man could be the father, and more tests are needed to discern paternity. 
D) neither man in question is the child's biological father. 
A) the husband is definitely the child's father. 
B) the husband is definitely not the child's father. 
C) either man could be the father, and more tests are needed to discern paternity. 
D) neither man in question is the child's biological father.

Question 12

Describe constitutive heterochromatin and facultative heterochromatin. Based upon this information,what would you predict would happen during the embryonic development of an organism if some regions of facultative heterochromatin were changed to constitutive regions?

Accepted Answer

Constitutive heterochromatin exists in a

Question 13

The protein ________ is very important for the investigation of protein products produced by an organism.

Accepted Answer

The answer of The protein ________ is very important for...

Question 14

Common SNPs may be important in causing ________ in humans or in ________ of disorders.

Accepted Answer

The answer of Common SNPs may be important in causing...

Question 15

You are given the task of restriction-mapping a portion of a chromosome.Given is a 7.0 kb fragment.You digest the fragment with BamHI and,upon gel electrophoresis,observe a band at 5.0 kb and 1.0 kb.When you digest the fragment with the enzyme HindII,you observe fragment bands at 4 kb and 3 kb.When you digest the 7.0 kb fragment with both enzymes,you observe bands at 3 kb,2 kb,and 1 kb.Based on this information,draw the restriction map of the 7 kb fragment.

Accepted Answer

The answer of You are given the task of restriction-mapping...

Question 16

A variety of E.coli clones have been isolated,and the DNA has been extracted,digested with restriction enzymes,denatured,separated by gel electrophoresis,and transferred to nylon membrane by the Southern blot procedure.A radioactive probe is used that hybridizes with a gene of interest.The DNA corresponding to a single clone yields a single DNA band after probing the blot.Based on this information only,

Accepted Answer

A) all of the clones tested, except the one described, have the gene of interest. 
B) only the one clone described has the gene of interest. 
C) the gene of interest is located entirely on the DNA band visualized. 
D) the part of the gene recognized by the probe is located on the DNA band visualized. 
E) both choices B and D 
A) all of the clones tested, except the one described, have the gene of interest. 
B) only the one clone described has the gene of interest. 
C) the gene of interest is located entirely on the DNA band visualized. 
D) the part of the gene recognized by the probe is located on the DNA band visualized. 
E) both choices B and D

Question 17

Following reports that stained chromosomes "disappeared" while observing cell division,scientists in the early 1900s determined the molecule of heredity to be

Accepted Answer

A) DNA. 
B) RNA. 
C) protein. 
D) lipids. 
E) carbohydrates. 
A) DNA. 
B) RNA. 
C) protein. 
D) lipids. 
E) carbohydrates.

Question 18

You are given two samples of DNA,one from Clostridium perfringens and the other from Mycobacterium tuberculosis.Unfortunately,the labels on the tubes of DNA were accidently removed,and you do not know which DNA sample belongs to which organism.As you were doing some work with Escherichia coli in the lab,you also have some of its DNA available as well.The %G+C values for each of the organisms is known (C.perfringens,27%; M.tuberculosis,67%; E.coli,50%).Based upon this information,how could you quickly determine the source of the DNA for your two samples?

Accepted Answer

A thermal denaturation curve could be pe

Question 19

Avery,MacLeod,and McCarty (1944)demonstrated that DNA was the molecule of heredity by treating heat-killed Streptococcus pneumoniae S (smooth)strain with DNase,thereby preventing transfer of the "transforming substance" from the killed S strain to the live R (rough)strain when the two were mixed together and injected into mice.Another way that one could demonstrate transformation in bacteria would be to extract DNA from

Accepted Answer

A) an R strain and mix with cells of an S strain. 
B) both S and R strains and mix to allow recombination to take place. 
C) an ampicillin-sensitive strain and mix with cells of an ampicillin-resistant strain. 
D) an S strain and mix with cells of an R strain. 
E) none of the above 
A) an R strain and mix with cells of an S strain. 
B) both S and R strains and mix to allow recombination to take place. 
C) an ampicillin-sensitive strain and mix with cells of an ampicillin-resistant strain. 
D) an S strain and mix with cells of an R strain. 
E) none of the above

Question 20

SNPs located near each other on chromosomes are inherited as blocks known as ________.

Accepted Answer

The answer of SNPs located near each other on chromosomes...

Base sequence variations between individuals that result from point mutations are called

The ________ is the entire set of proteins expressed by a genome.

An example of a purine is

With regard to DNA packaging,prokaryotic chromosomes

Circular DNA molecules found in nature (such as bacterial,viral,or mitochondrial DNA)are

Two common transposable elements associated with interspersed repeated DNA are and .

Restriction enzymes typically recognize

Because of its antiparallel nature,DNA is often referred to as a ________.

Which of the following are components of Chargaff's rules of bases?

Describe constitutive heterochromatin and facultative heterochromatin. Based upon this information,what would you predict would happen during the embryonic development of an organism if some regions of facultative heterochromatin were changed to constitutive regions?

The protein ________ is very important for the investigation of protein products produced by an organism.

Common SNPs may be important in causing in humans or in of disorders.

Following reports that stained chromosomes "disappeared" while observing cell division,scientists in the early 1900s determined the molecule of heredity to be

SNPs located near each other on chromosomes are inherited as blocks known as ________.

A Preview of the Cell

The Chemistry of the Cell

The Macromolecules of the Cell

Cells and Organelles

Bioenergetics: the Flow of Energy in the Cell

Enzymes: the Catalysts of Life

Membranes: Their Structure, function, and Chemistry

Transport Across Membranes: Overcoming the Permeability Barrier

Chemotrophic Energy Metabolism: Glycolysis and Fermentation

Chemotrophic Energy Metabolism: Aerobic Respiration

Phototrophic Energy Metabolism: Photosynthesis

The Endomembrane System and Peroxisomes

Signal Transduction Mechanisms: Ielectrical and Synaptic Signaling in Neurons

Signal Transduction Mechanisms: Iimessengers and Receptors

Cytoskeletal Systems

Cellular Movement: Motility and Contractility

Beyond the Cell: Cell Adhesions, cell Junctions, and Extracellular Structures

The Cell Cycle, DNA Replication, and Mitosis

Sexual Reproduction, meiosis, and Genetic Recombination

Gene Expression: Ithe Genetic Code and Transcription

Gene Expression: Iiprotein Synthesis and Sorting

The Regulation of Gene Expression

Cancer Cells

Filters

Exam 18: The Structural Basis of Cellular Information: DNA, chromosomes, and the Nucleus

Base sequence variations between individuals that result from point mutations are called

The ________ is the entire set of proteins expressed by a genome.

An example of a purine is

With regard to DNA packaging,prokaryotic chromosomes

Circular DNA molecules found in nature (such as bacterial,viral,or mitochondrial DNA)are

Two common transposable elements associated with interspersed repeated DNA are ________ and ________.

Restriction enzymes typically recognize

Because of its antiparallel nature,DNA is often referred to as a ________.

Which of the following are components of Chargaff's rules of bases?

Describe constitutive heterochromatin and facultative heterochromatin. Based upon this information,what would you predict would happen during the embryonic development of an organism if some regions of facultative heterochromatin were changed to constitutive regions?

The protein ________ is very important for the investigation of protein products produced by an organism.

Common SNPs may be important in causing ________ in humans or in ________ of disorders.

Following reports that stained chromosomes "disappeared" while observing cell division,scientists in the early 1900s determined the molecule of heredity to be

SNPs located near each other on chromosomes are inherited as blocks known as ________.

A Preview of the Cell

The Chemistry of the Cell

The Macromolecules of the Cell

Cells and Organelles

Bioenergetics: the Flow of Energy in the Cell

Enzymes: the Catalysts of Life

Membranes: Their Structure, function, and Chemistry

Transport Across Membranes: Overcoming the Permeability Barrier

Chemotrophic Energy Metabolism: Glycolysis and Fermentation

Chemotrophic Energy Metabolism: Aerobic Respiration

Phototrophic Energy Metabolism: Photosynthesis

The Endomembrane System and Peroxisomes

Signal Transduction Mechanisms: Ielectrical and Synaptic Signaling in Neurons

Signal Transduction Mechanisms: Iimessengers and Receptors

Cytoskeletal Systems

Cellular Movement: Motility and Contractility

Beyond the Cell: Cell Adhesions, cell Junctions, and Extracellular Structures

The Cell Cycle, DNA Replication, and Mitosis

Sexual Reproduction, meiosis, and Genetic Recombination

Gene Expression: Ithe Genetic Code and Transcription

Gene Expression: Iiprotein Synthesis and Sorting

The Regulation of Gene Expression

Cancer Cells

Filters

Two common transposable elements associated with interspersed repeated DNA are and .

Common SNPs may be important in causing in humans or in of disorders.