Question 1

Which of the following codons is associated with the amino acid phenylalanine?

Accepted Answer

A) AAA 
B) UAG 
C) AUG 
D) AAC 
E) UUU 
A) AAA 
B) UAG 
C) AUG 
D) AAC 
E) UUU E

Question 2

In studying an E.coli strain containing a known frameshift mutation,you isolate a mutant in which this frameshift is suppressed.You therefore expect to find which of the following associated with the suppression? (Assume the frameshift has not been corrected in the coding for the peptide.)

Accepted Answer

A) suppressor tRNAs encode an amino acid for a stop signal 
B) suppressor tRNAs encode a four-nucleotide anticodon 
C) suppressor tRNAs encode a two-nucleotide anticodon 
D) both choices B and C 
E) all of the above 
A) suppressor tRNAs encode an amino acid for a stop signal 
B) suppressor tRNAs encode a four-nucleotide anticodon 
C) suppressor tRNAs encode a two-nucleotide anticodon 
D) both choices B and C 
E) all of the above D

Question 3

Match between columns
                        Premises: tRNA
peptidyl transferase
30S ribosomal subunit
stop codon
aminoacyl-tRNA synthetase
RNA polymerase
16S rRNA
elongation factor G
start codon
release factor

Accepted Answer

The Answer of AUG and catalyzes translocation of the ribosome is...

Question 4

Of the following steps associated with translation,which does not involve hydrolysis of GTP?

Accepted Answer

A) aminoacylation of tRNA 
B) formation of the initiation complex 
C) binding of the aminoacyl tRNA to the codon at the A site 
D) translocation of the ribosome 
E) release of polypeptide 
A) aminoacylation of tRNA 
B) formation of the initiation complex 
C) binding of the aminoacyl tRNA to the codon at the A site 
D) translocation of the ribosome 
E) release of polypeptide

Question 5

Which of the following organelles does not receive proteins synthesized on cytoplasmic ribosomes by posttranslational import?

Accepted Answer

A) lysosome 
B) nucleus 
C) mitochondria 
D) peroxisomes 
E) chloroplast 
A) lysosome 
B) nucleus 
C) mitochondria 
D) peroxisomes 
E) chloroplast

Question 6

Peptide bond formation is catalyzed by an RNA molecule in

Accepted Answer

A) prokaryotes. 
B) eukaryotes. 
C) yeast only. 
D) cyanobacteria. 
E) both choices A and B 
A) prokaryotes. 
B) eukaryotes. 
C) yeast only. 
D) cyanobacteria. 
E) both choices A and B

Question 7

________ is a rare,intramolecular posttranslational process that allows for self-catalytic removal of specific amino acid sequences.

Accepted Answer

The answer of ________ is a rare,intramolecular posttranslational process that...

Question 8

Which of the following enzymes is associated with the formation of peptide binds?

Accepted Answer

A) peptidase 
B) aminoacyl transferase 
C) peptidyl transferase 
D) peptide hydrolase 
E) inteins 
A) peptidase 
B) aminoacyl transferase 
C) peptidyl transferase 
D) peptide hydrolase 
E) inteins

Question 9

Which of the following activities is not associated with posttranslational processing?

Accepted Answer

A) glycosylation 
B) specific cleavage of polypeptides 
C) chaperonin activity 
D) addition of lipid groups 
E) polyadenylation 
A) glycosylation 
B) specific cleavage of polypeptides 
C) chaperonin activity 
D) addition of lipid groups 
E) polyadenylation

Question 10

Within the endoplasmic reticulum,________ recognizes misfolded or unassembled proteins and transports them back to the cytosol.

Accepted Answer

ER-associa

Question 11

Polycistronic mRNAs encode

Accepted Answer

A) one product that it alternatively spliced. 
B) more than one protein. 
C) a single message. 
D) exclusively archaeal proteins. 
E) none of the above 
A) one product that it alternatively spliced. 
B) more than one protein. 
C) a single message. 
D) exclusively archaeal proteins. 
E) none of the above

Question 12

Messenger RNAs that contain no stop codons due to a frameshift mutation are eliminated by

Accepted Answer

A) nonstop decay. 
B) directed RNase activity. 
C) nonsense-mediated decay. 
D) error-mediated repair. 
E) none of the above 
A) nonstop decay. 
B) directed RNase activity. 
C) nonsense-mediated decay. 
D) error-mediated repair. 
E) none of the above

Question 13

The transfer of polypeptides into the ER is called ________ because the movement across the membrane is coupled with translation.

Accepted Answer

cotranslat

Question 14

Which of the following steps in prokaryotic translation takes place first?

Accepted Answer

A) aminoacylation of the tRNA molecule 
B) joining of 30S and 50S ribosomal subunits into 70S ribsomes 
C) binding of mRNA to a ribosome 
D) attachment of fMet aminoacyl tRNA 
E) catalysis by RNA polymerase 
A) aminoacylation of the tRNA molecule 
B) joining of 30S and 50S ribosomal subunits into 70S ribsomes 
C) binding of mRNA to a ribosome 
D) attachment of fMet aminoacyl tRNA 
E) catalysis by RNA polymerase

Question 15

Which of the following requires eIFs for initiation?

Accepted Answer

A) E. coli translation 
B) chaperonin activity 
C) eukaryotic translation 
D) eukaryotic transcription 
E) DNA replication 
A) E. coli translation 
B) chaperonin activity 
C) eukaryotic translation 
D) eukaryotic transcription 
E) DNA replication

Question 16

Using the techniques of genetic engineering,you design a cytoplasmic protein you want to accumulate within the ER of yeast cells.To accomplish this goal,you need to

Accepted Answer

A) do nothing; all proteins go through the ER. 
B) incorporate appropriate mannose-6-phosphate groups. 
C) incorporate the appropriate DNA sequence(s)to create signal sequences into mature peptide. 
D) incorporate radioactive amino acids into the protein. 
E) incorporate the appropriate DNA sequence(s)to create signal sequences into the mature peptide. 
A) do nothing; all proteins go through the ER. 
B) incorporate appropriate mannose-6-phosphate groups. 
C) incorporate the appropriate DNA sequence(s)to create signal sequences into mature peptide. 
D) incorporate radioactive amino acids into the protein. 
E) incorporate the appropriate DNA sequence(s)to create signal sequences into the mature peptide.

Question 17

The initial amino acid incorporated into a nascent peptide is N-formylated in

Accepted Answer

A) eukaryotic translation. 
B) prokaryotic transcription. 
C) prokaryotic translation. 
D) both choices A and C 
E) both choices B and C 
A) eukaryotic translation. 
B) prokaryotic transcription. 
C) prokaryotic translation. 
D) both choices A and C 
E) both choices B and C

Question 18

Which of the following is not a prion disease?

Accepted Answer

A) scrapie 
B) tuberculosis 
C) mad cow disease 
D) Creutzfeldt-Jacob disease 
A) scrapie 
B) tuberculosis 
C) mad cow disease 
D) Creutzfeldt-Jacob disease

Question 19

Design an experiment whereby you could determine that the genetic code of a novel organism is based on a four-nucleotide codon.

Accepted Answer

Although answers will vary,all

Question 20

In the following gene sequence,the original sequence is ABC* DEFGH. It now reads ABC* DGFEH.The * indicates the centromere. This type of mutation is a(n)

Accepted Answer

A) nonsense mutation. 
B) inversion. 
C) translocation. 
D) duplication. 
E) point mutation. 
A) nonsense mutation. 
B) inversion. 
C) translocation. 
D) duplication. 
E) point mutation.

Exam 22: Gene Expression: Iiprotein Synthesis and Sorting

Which of the following codons is associated with the amino acid phenylalanine?

In studying an E.coli strain containing a known frameshift mutation,you isolate a mutant in which this frameshift is suppressed.You therefore expect to find which of the following associated with the suppression? (Assume the frameshift has not been corrected in the coding for the peptide.)

Of the following steps associated with translation,which does not involve hydrolysis of GTP?

Which of the following organelles does not receive proteins synthesized on cytoplasmic ribosomes by posttranslational import?

Peptide bond formation is catalyzed by an RNA molecule in

________ is a rare,intramolecular posttranslational process that allows for self-catalytic removal of specific amino acid sequences.

Which of the following enzymes is associated with the formation of peptide binds?

Which of the following activities is not associated with posttranslational processing?

Within the endoplasmic reticulum,________ recognizes misfolded or unassembled proteins and transports them back to the cytosol.

Polycistronic mRNAs encode

Messenger RNAs that contain no stop codons due to a frameshift mutation are eliminated by

The transfer of polypeptides into the ER is called ________ because the movement across the membrane is coupled with translation.

Which of the following steps in prokaryotic translation takes place first?

Which of the following requires eIFs for initiation?

Using the techniques of genetic engineering,you design a cytoplasmic protein you want to accumulate within the ER of yeast cells.To accomplish this goal,you need to

The initial amino acid incorporated into a nascent peptide is N-formylated in

Which of the following is not a prion disease?

Design an experiment whereby you could determine that the genetic code of a novel organism is based on a four-nucleotide codon.

In the following gene sequence,the original sequence is ABC* DEFGH. It now reads ABC* DGFEH.The * indicates the centromere. This type of mutation is a(n)

A Preview of the Cell

The Chemistry of the Cell

The Macromolecules of the Cell

Cells and Organelles

Bioenergetics: the Flow of Energy in the Cell

Enzymes: the Catalysts of Life

Membranes: Their Structure, function, and Chemistry

Transport Across Membranes: Overcoming the Permeability Barrier

Chemotrophic Energy Metabolism: Glycolysis and Fermentation

Chemotrophic Energy Metabolism: Aerobic Respiration

Phototrophic Energy Metabolism: Photosynthesis

The Endomembrane System and Peroxisomes

Signal Transduction Mechanisms: Ielectrical and Synaptic Signaling in Neurons

Signal Transduction Mechanisms: Iimessengers and Receptors

Cytoskeletal Systems

Cellular Movement: Motility and Contractility

Beyond the Cell: Cell Adhesions, cell Junctions, and Extracellular Structures

The Structural Basis of Cellular Information: DNA, chromosomes, and the Nucleus

The Cell Cycle, DNA Replication, and Mitosis

Sexual Reproduction, meiosis, and Genetic Recombination

Gene Expression: Ithe Genetic Code and Transcription

The Regulation of Gene Expression

Cancer Cells

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