Question 1

Which enzyme is involved in proofreading during DNA replication?

Accepted Answer

A) 5' to 3' exonuclease 
B) 3' to 5' exonuclease 
C) 5' to 3' endonuclease 
D) 3' to 5' endonuclease 
E) DNA polymerase 
A) 5' to 3' exonuclease 
B) 3' to 5' exonuclease 
C) 5' to 3' endonuclease 
D) 3' to 5' endonuclease 
E) DNA polymerase

Question 2

Ultraviolet (UV)light-treated bacteria would most likely have DNA damage in the form of

Accepted Answer

A) analog incorporation. 
B) pyrimidine dimer formation. 
C) intercalation of the bases. 
D) direct transition of the bases. 
E) deamination. 
A) analog incorporation. 
B) pyrimidine dimer formation. 
C) intercalation of the bases. 
D) direct transition of the bases. 
E) deamination.

Question 3

An isolate of a mutant bacterium appears to grow more slowly than the population (wild type)from which it was isolated.Further studies showed that the slower growth was due to a markedly reduced DNA polymerase I activity.From this information,one would expect that this organism would also be deficient in the activity of DNA

Accepted Answer

A) excision repair. 
B) recombination. 
C) transcription. 
D) translation. 
E) unwinding. 
A) excision repair. 
B) recombination. 
C) transcription. 
D) translation. 
E) unwinding.

Question 4

In order to be active,a Cdc-cyclin needs to be

Accepted Answer

A) singly phosphorylated. 
B) acetylated. 
C) doubly phosphorylated. 
D) doubly methylated. 
E) cleaved by proteases. 
A) singly phosphorylated. 
B) acetylated. 
C) doubly phosphorylated. 
D) doubly methylated. 
E) cleaved by proteases.

Question 5

What is the ploidy of an organism that is 7n,where n = 5?

Accepted Answer

A) 5 
B) 7 
C) 12 
D) 35 
E) 57 
A) 5 
B) 7 
C) 12 
D) 35 
E) 57

Question 6

All of the following are associated with replicons except

Accepted Answer

A) origin of replication. 
B) single-strand binding proteins. 
C) initiator proteins. 
D) minichromosome maintenance proteins. 
E) helicase loaders. 
A) origin of replication. 
B) single-strand binding proteins. 
C) initiator proteins. 
D) minichromosome maintenance proteins. 
E) helicase loaders.

Question 7

Cyclins modulate the progression of cells through the cell cycle by

Accepted Answer

A) directly activating G proteins. 
B) inducing synthesis of constitutively active forms of growth cell receptors. 
C) activating protein kinases that are critical regulators of cell division. 
D) degrading histones. 
E) increasing the production of DNA polymerases. 
A) directly activating G proteins. 
B) inducing synthesis of constitutively active forms of growth cell receptors. 
C) activating protein kinases that are critical regulators of cell division. 
D) degrading histones. 
E) increasing the production of DNA polymerases.

Question 8

Using specific examples,distinguish between those mutations that are spontaneous and those that are the result of exposure to substances.How might some of the exposures be used in cellular biology?

Accepted Answer

Spontaneous mutations are those that are

Question 9

The multiple sites of DNA replication along eukaryotic chromosomes are known as

Accepted Answer

A) replicons. 
B) multireplication forks. 
C) helicase loaders. 
D) ARS elements. 
E) none of the above 
A) replicons. 
B) multireplication forks. 
C) helicase loaders. 
D) ARS elements. 
E) none of the above

Question 10

Why do eukaryotic chromosomes have multiple origins of replication? Design an experiment that allows you to test your hypothesis.

Accepted Answer

Multiple origin of replication sites all

Question 11

In a cell with a diploid number of 12,how many chromatids are present at prophase of mitosis?

Accepted Answer

A) 6 
B) 12 
C) 24 
D) 48 
E) none of the above 
A) 6 
B) 12 
C) 24 
D) 48 
E) none of the above

Question 12

Which of the following statements regarding Fas-mediated programmed cell death is false?

Accepted Answer

A) Fas ligand binding with Fas receptor stimulates a specific G protein. 
B) Fas ligand and receptor interaction results in the recruitment of adaptor proteins in the target cell. 
C) Capases are activated in the process. 
D) The caspase cascade results in the cleavage of the proteins within the target cell. 
E) It ultimately results in death of the cell. 
A) Fas ligand binding with Fas receptor stimulates a specific G protein. 
B) Fas ligand and receptor interaction results in the recruitment of adaptor proteins in the target cell. 
C) Capases are activated in the process. 
D) The caspase cascade results in the cleavage of the proteins within the target cell. 
E) It ultimately results in death of the cell.

Question 13

Which of the following would not inhibit a cell preparing to undergo mitosis?

Accepted Answer

A) chromosomal abnormalities 
B) Cdc-activating kinase activity 
C) Chk1 inhibtion of Cdc25 
D) p21 inhibition of G₁ 
E) environmental signals that no new cells are needed 
A) chromosomal abnormalities 
B) Cdc-activating kinase activity 
C) Chk1 inhibtion of Cdc25 
D) p21 inhibition of G₁ 
E) environmental signals that no new cells are needed

Question 14

During the G2 checkpoint in eukaryotic cells,the cell is assessed with regard to

Accepted Answer

A) DNA replication. 
B) chromosome attachment to the spindle. 
C) nutrients. 
D) DNA damage. 
E) presence of growth factors. 
A) DNA replication. 
B) chromosome attachment to the spindle. 
C) nutrients. 
D) DNA damage. 
E) presence of growth factors.

Question 15

Which of the following eukaryotic DNA polymerases replicates mitochondrial DNA?

Accepted Answer

A) alpha 
B) beta 
C) delta 
D) epsilon 
E) gamma 
A) alpha 
B) beta 
C) delta 
D) epsilon 
E) gamma

Question 16

Starting with a cell (2n = 4),illustrate the phases of mitosis with emphasis on the division of chromosomes.

Accepted Answer

The answer of Starting with a cell (2n = 4),illustrate...

Question 17

The phase of the cell cycle that varies most in duration in various cell types is

Accepted Answer

A) M. 
B) G₁. 
C) S. 
D) G₂. 
E) both choices A and B 
A) M. 
B) G₁. 
C) S. 
D) G₂. 
E) both choices A and B

Question 18

All of the following participate in apoptosis except

Accepted Answer

A) caspases. 
B) death-promoting proteins. 
C) mitochondria. 
D) Bcl-2. 
E) calcium ions. 
A) caspases. 
B) death-promoting proteins. 
C) mitochondria. 
D) Bcl-2. 
E) calcium ions.

Question 19

Why does DNA contain thymine over uracil? What effect would the presence of uracil in the DNA have on repair?

Accepted Answer

Deamination of cytosine result

Question 20

Analysis of chromosomes in metaphase of mitosis is known as ________ .

Accepted Answer

The answer of Analysis of chromosomes in metaphase of mitosis...

Exam 19: The Cell Cycle, DNA Replication, and Mitosis

Which enzyme is involved in proofreading during DNA replication?

Ultraviolet (UV)light-treated bacteria would most likely have DNA damage in the form of

In order to be active,a Cdc-cyclin needs to be

What is the ploidy of an organism that is 7n,where n = 5?

All of the following are associated with replicons except

Cyclins modulate the progression of cells through the cell cycle by

Using specific examples,distinguish between those mutations that are spontaneous and those that are the result of exposure to substances.How might some of the exposures be used in cellular biology?

The multiple sites of DNA replication along eukaryotic chromosomes are known as

Why do eukaryotic chromosomes have multiple origins of replication? Design an experiment that allows you to test your hypothesis.

In a cell with a diploid number of 12,how many chromatids are present at prophase of mitosis?

Which of the following statements regarding Fas-mediated programmed cell death is false?

Which of the following would not inhibit a cell preparing to undergo mitosis?

During the G2 checkpoint in eukaryotic cells,the cell is assessed with regard to

Which of the following eukaryotic DNA polymerases replicates mitochondrial DNA?

Starting with a cell (2n = 4),illustrate the phases of mitosis with emphasis on the division of chromosomes.

The phase of the cell cycle that varies most in duration in various cell types is

All of the following participate in apoptosis except

Why does DNA contain thymine over uracil? What effect would the presence of uracil in the DNA have on repair?

Analysis of chromosomes in metaphase of mitosis is known as ________ .

A Preview of the Cell

The Chemistry of the Cell

The Macromolecules of the Cell

Cells and Organelles

Bioenergetics: the Flow of Energy in the Cell

Enzymes: the Catalysts of Life

Membranes: Their Structure, function, and Chemistry

Transport Across Membranes: Overcoming the Permeability Barrier

Chemotrophic Energy Metabolism: Glycolysis and Fermentation

Chemotrophic Energy Metabolism: Aerobic Respiration

Phototrophic Energy Metabolism: Photosynthesis

The Endomembrane System and Peroxisomes

Signal Transduction Mechanisms: Ielectrical and Synaptic Signaling in Neurons

Signal Transduction Mechanisms: Iimessengers and Receptors

Cytoskeletal Systems

Cellular Movement: Motility and Contractility

Beyond the Cell: Cell Adhesions, cell Junctions, and Extracellular Structures

The Structural Basis of Cellular Information: DNA, chromosomes, and the Nucleus

Sexual Reproduction, meiosis, and Genetic Recombination

Gene Expression: Ithe Genetic Code and Transcription

Gene Expression: Iiprotein Synthesis and Sorting

The Regulation of Gene Expression

Cancer Cells

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