Exam 6: Mechanisms of Enzymes

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A histidine was determined to be the critical residue involved in an enzyme-catalyzed reaction.If the pKa of the histidine is known to be 6.5 in the active site and the pH of maximum catalytic activity is 7.2,what is likely the primary role of histidine in the catalytic reaction?

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A chemical group that has a negative charge or an unshared electron pair may act as a(n)

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The enzyme has an active site which

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Which statement describes the mechanism of lysozyme's catalyzed reaction?

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If a plot of enzyme activity versus pH is sigmoidal then acid-base catalysis can be ruled out as a mode of catalysis.

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Superoxide dismutase enzyme catalysis is faster than the rate of diffusion because it

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Which amino acid is least likely to participate in acid-base catalysis?

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The mechanism of action of lysozyme includes

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