Question 1

What may result when grafted tissue such as bone marrow contains passenger lymphocytes?

Accepted Answer

A) Formation of autoantibodies 
B) Host rejection of graft 
C) Hypogammaglobulinemia 
D) Graft versus host disease 
A) Formation of autoantibodies 
B) Host rejection of graft 
C) Hypogammaglobulinemia 
D) Graft versus host disease

Question 2

Autoimmune diseases and immunodeficiencies are studied and treated by immunopathologists.

Accepted Answer

A) True 
 B)False

Question 3

What will be the immediate action of an allergen when it enters the body for a second time?

Accepted Answer

A) Binding of allergen to adjacent IgE binding sites on mast cells and basophils 
B) Histamine acts on smooth muscle 
C) Prostaglandins cause vasodilation and increased vascular permeability 
D) Binding of IgE by the Fc region to mast cells and basophils 
E) Degranulation 
A) Binding of allergen to adjacent IgE binding sites on mast cells and basophils 
B) Histamine acts on smooth muscle 
C) Prostaglandins cause vasodilation and increased vascular permeability 
D) Binding of IgE by the Fc region to mast cells and basophils 
E) Degranulation

Question 4

Tissue transplanted from one body site on a patient to a different body site on that patient is called a(n) ______.

Accepted Answer

A) allograft 
B) xenograft 
C) isograft 
D) hypograft 
E) autograft 
A) allograft 
B) xenograft 
C) isograft 
D) hypograft 
E) autograft

Question 5

John, a Peace Corps worker in the country of Mali in Africa, was in a car accident while traveling through a rural area.He was treated at a tiny rural hospital, and due to his loss of blood, he required a transfusion.John has B- blood type and has never received a transfusion before.Which statement is correct regarding this scenario?

Accepted Answer

A) He can be given types O or B, no matter whether Rh- or Rh+.At this point in time, he does not have anti-Rh antibody.O has no antigens on the blood cells, so he is also safe to receive that type in addition to his own B type. 
B) He can safely receive O- blood even though he makes anti-A antibodies. 
C) He can be given A+ blood type in addition to B+.Rh- means that he makes no antibody to Rh. 
D) The preferred blood type to give John, in addition to his own B type blood, would be AB.Both types of blood have the B antigen on the cells, so they would correspond to his own antigens.As for Rh, he can receive only Rh- blood since he would have a reaction against Rh+. 
A) He can be given types O or B, no matter whether Rh- or Rh+.At this point in time, he does not have anti-Rh antibody.O has no antigens on the blood cells, so he is also safe to receive that type in addition to his own B type. 
B) He can safely receive O- blood even though he makes anti-A antibodies. 
C) He can be given A+ blood type in addition to B+.Rh- means that he makes no antibody to Rh. 
D) The preferred blood type to give John, in addition to his own B type blood, would be AB.Both types of blood have the B antigen on the cells, so they would correspond to his own antigens.As for Rh, he can receive only Rh- blood since he would have a reaction against Rh+.

Question 6

Infection with enteroviruses, such as rotavirus and cytomegalovirus, has been implicated in the onset of type I diabetes.This area of research involves the study of ______.

Accepted Answer

A) molecular mimicry 
B) forbidden clones 
C) the gut microbiome 
D) sequestered antigens 
A) molecular mimicry 
B) forbidden clones 
C) the gut microbiome 
D) sequestered antigens

Question 7

A chronic, local allergy such as hay fever is considered ______.

Accepted Answer

A) antibody-mediated 
B) atopic 
C) systemic anaphylactic 
D) delayed 
E) T-cell-mediated 
A) antibody-mediated 
B) atopic 
C) systemic anaphylactic 
D) delayed 
E) T-cell-mediated

Question 8

A systemic, sometimes fatal, reaction with airway obstruction and circulatory collapse is ______.

Accepted Answer

A) atopic 
B) delayed 
C) systemic anaphylaxis 
D) antibody-mediated 
E) T-cell-mediated 
A) atopic 
B) delayed 
C) systemic anaphylaxis 
D) antibody-mediated 
E) T-cell-mediated

Question 9

The tuberculin reaction develops within 30 minutes of the skin test in people with prior sensitization due to tuberculosis infection.

Accepted Answer

A) True 
 B)False

Question 10

Atopy and anaphylaxis are hypersensitivities in the category(ies)

Accepted Answer

A) type I only. 
B) type I and type IV. 
C) type IV only. 
D) type I, type II, and type III. 
E) type I, type II, type III, and type IV. 
A) type I only. 
B) type I and type IV. 
C) type IV only. 
D) type I, type II, and type III. 
E) type I, type II, type III, and type IV.

Question 11

The potential for hemolytic disease of the newborn occurs when

Accepted Answer

A) fetal Rh- cells enter an Rh+ mother. 
B) fetal Rh+ cells enter an Rh+ mother. 
C) maternal Rh+ cells enter an Rh- fetus. 
D) fetal Rh+ cells enter an Rh- mother. 
E) maternal Rh- cells enter an Rh+ fetus. 
A) fetal Rh- cells enter an Rh+ mother. 
B) fetal Rh+ cells enter an Rh+ mother. 
C) maternal Rh+ cells enter an Rh- fetus. 
D) fetal Rh+ cells enter an Rh- mother. 
E) maternal Rh- cells enter an Rh+ fetus.

Question 12

A person with O type blood

Accepted Answer

A) lacks A and B antigens. 
B) is called a universal recipient. 
C) lacks all of the alleles for ABO blood type. 
D) could not have the Rh factor. 
A) lacks A and B antigens. 
B) is called a universal recipient. 
C) lacks all of the alleles for ABO blood type. 
D) could not have the Rh factor.

Question 13

Degranulation of mast cells leads to
A.decreased mucus production.
B.constriction of blood vessels.
C.lymph node swelling.
D.constricted bronchioles.

Accepted Answer

A. decreased mucus production.

Question 14

The study of diseases associated with excesses and deficiencies of the immune system is ______.

Accepted Answer

A) humoralpathology 
B) hemopathology 
C) epidemiology 
D) immunopathology 
E) histopathology 
A) humoralpathology 
B) hemopathology 
C) epidemiology 
D) immunopathology 
E) histopathology

Question 15

What can be a consequence of a genetic deficiency in B-cell survival and maturity?

Accepted Answer

A) Graft versus host disease 
B) Formation of autoantibodies 
C) Hypogammaglobulinemia 
D) Host rejection of graft 
A) Graft versus host disease 
B) Formation of autoantibodies 
C) Hypogammaglobulinemia 
D) Host rejection of graft

Question 16

A person who produces anti-A and anti-B serum antibodies will have blood type ______.

Accepted Answer

A) Rh 
B) A 
C) AB 
D) O 
E) B 
A) Rh 
B) A 
C) AB 
D) O 
E) B

Question 17

In the theory for allergic desensitization, which immunoglobulin blocks the allergen from binding with IgE?

Accepted Answer

A) IgD 
B) IgE 
C) IgA 
D) IgM 
E) IgG 
A) IgD 
B) IgE 
C) IgA 
D) IgM 
E) IgG

Question 18

AIDS is a secondary immunodeficiency disease that affects several types of immune cells.

Accepted Answer

A) True 
 B)False

Question 19

All of the following represent potential therapy for patients with SCID except

Accepted Answer

A) stem cell grafts. 
B) graft versus host. 
C) transfusion with adensosine deaminase. 
D) gene therapy. 
E) bone marrow transplants. 
A) stem cell grafts. 
B) graft versus host. 
C) transfusion with adensosine deaminase. 
D) gene therapy. 
E) bone marrow transplants.

Question 20

You were out in the garage going through boxes when you were bitten by an a spider.You tell the doctor that the spider was tiny and black, causing the doctor to think perhaps that it was a black widow spider The doctor gives you an injection of antibody to the spider venom to give you immediate protection.The antibody is produced in horses by injecting them with small doses of the spider venom, causing the horse's immune system to make large amounts of specific antibody to the antigen.The horse serum is then purified before being given to humans.
A.a Staphylococcus infection related to the spider bite.
B.serum sickness.
C.a delayed type hypersensitivity mediated by cytotoxic T cells along with helper T cells.
D.Arthus reaction.
E.anaphylactic shock.

Accepted Answer

A week later, you notice a red rash spre

Exam 16: Disorders in Immunity

What may result when grafted tissue such as bone marrow contains passenger lymphocytes?

Autoimmune diseases and immunodeficiencies are studied and treated by immunopathologists.

What will be the immediate action of an allergen when it enters the body for a second time?

Tissue transplanted from one body site on a patient to a different body site on that patient is called a(n) ______.

Infection with enteroviruses, such as rotavirus and cytomegalovirus, has been implicated in the onset of type I diabetes.This area of research involves the study of ______.

A chronic, local allergy such as hay fever is considered ______.

A systemic, sometimes fatal, reaction with airway obstruction and circulatory collapse is ______.

The tuberculin reaction develops within 30 minutes of the skin test in people with prior sensitization due to tuberculosis infection.

Atopy and anaphylaxis are hypersensitivities in the category(ies)

The potential for hemolytic disease of the newborn occurs when

A person with O type blood

Degranulation of mast cells leads to A.decreased mucus production. B.constriction of blood vessels. C.lymph node swelling. D.constricted bronchioles.

The study of diseases associated with excesses and deficiencies of the immune system is ______.

What can be a consequence of a genetic deficiency in B-cell survival and maturity?

A person who produces anti-A and anti-B serum antibodies will have blood type ______.

In the theory for allergic desensitization, which immunoglobulin blocks the allergen from binding with IgE?

AIDS is a secondary immunodeficiency disease that affects several types of immune cells.

All of the following represent potential therapy for patients with SCID except

The Main Themes of Microbiology

The Chemistry of Biology

Tools of the Laboratory: Methods for the Culturing of Microscopic Analysis of Microorganisms

Bacteria and Archaea

Eukaryotic Cells and Microorganisms

An Introduction to the Viruses

Microbial Nutrition, Ecology, and Growth

Microbial Metabolism: The Chemical Crossroads of Life

Microbial Genetics

Genetic Engineering and Recombinant Dna

Physical and Chemical Control of Microbes

Antimicrobial Treatment

Microbe-Human Interactions: Health and Disease

Host Defenses I: Overview and Nonspecific Defenses

Host Defenses II: Specific Immunity and Immunization

Diagnosing Infections

Infectious Diseases Affecting the Skin and Eyes

Infectious Diseases Affecting the Nervous System

Infectious Diseases Affecting the Cardiovascular and Lymphatic Systems

Infectious Diseases Affecting the Respiratory System

Infectious Diseases Affecting the Gastrointestinal Tract

Infectious Diseases Affecting the Genitourinary System

Microbes and the Environment

Applied Microbiology and Food and Water Safety

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