Question 1

Autoimmune diseases and immunodeficiencies are studied and treated by immunopathologists.

Accepted Answer

A) True 
 B)False

Question 2

The major category(ies)of hypersensitivity(ies)that typically involve(s)a B-cell immunoglobulin response include(s)

Accepted Answer

A)  type I only. 
B)  type I and type IV. 
C)  type IV only. 
D)  type I, type II, and type III. 
E)  type I, type II, type III, and type IV. 
A)  type I only. 
B)  type I and type IV. 
C)  type IV only. 
D)  type I, type II, and type III. 
E)  type I, type II, type III, and type IV.

Question 3

Myasthenia gravis disease arises from the production of autoantibodies against

Accepted Answer

A)  cells in thyroid follicles. 
B)  sodium pump proteins in the cell membrane. 
C)  acetylcholine receptors on smooth muscle. 
D)  myelin sheath cells of the nervous system. 
E)  acetylcholine receptors on skeletal muscle. 
A)  cells in thyroid follicles. 
B)  sodium pump proteins in the cell membrane. 
C)  acetylcholine receptors on smooth muscle. 
D)  myelin sheath cells of the nervous system. 
E)  acetylcholine receptors on skeletal muscle.

Question 4

Allergic reactions to penicillins are considered a(n)_____ hypersensitivity.

Accepted Answer

A)  T-cell-mediated 
B)  antibody-mediated 
C)  immune complex-mediated 
D)  immediate 
E)  Both T-cell-mediated and antibody-mediated are correct. 
A)  T-cell-mediated 
B)  antibody-mediated 
C)  immune complex-mediated 
D)  immediate 
E)  Both T-cell-mediated and antibody-mediated are correct.

Question 5

A viral infection can lead to the development of type I diabetes.

Accepted Answer

A) True 
 B)False

Question 6

A person with O type blood

Accepted Answer

A)  lacks A and B antigens. 
B)  is called a universal recipient. 
C)  lacks all of the alleles for ABO blood type. 
D)  could not have the Rh factor. 
A)  lacks A and B antigens. 
B)  is called a universal recipient. 
C)  lacks all of the alleles for ABO blood type. 
D)  could not have the Rh factor.

Question 7

Bee sting venom is considered to be which type of allergen?

Accepted Answer

A)  Injectant 
B)  Ingestant 
C)  Inhalant 
D)  Contactant 
A)  Injectant 
B)  Ingestant 
C)  Inhalant 
D)  Contactant

Question 8

Before a type II hypersensitivity can proceed,three immune components must be in place: complement,IgG,and IgM.

Accepted Answer

A) True 
 B)False

Question 9

Autoimmunity is typically due to

Accepted Answer

A)  autoantibodies and T cells. 
B)  a transfusion reaction. 
C)  IgE and mast cells. 
D)  graft rejection. 
E)  a deficiency in T-cell development. 
A)  autoantibodies and T cells. 
B)  a transfusion reaction. 
C)  IgE and mast cells. 
D)  graft rejection. 
E)  a deficiency in T-cell development.

Question 10

Food allergies include gastrointestinal symptoms and often hives.

Accepted Answer

A) True 
 B)False

Question 11

Which of the following is not a target for immune complex deposition?

Accepted Answer

A)  Heart and lungs 
B)  Brain 
C)  Kidneys 
D)  Joints 
E)  Blood vessels and skin 
A)  Heart and lungs 
B)  Brain 
C)  Kidneys 
D)  Joints 
E)  Blood vessels and skin

Question 12

A person who is Rh- will have anti-Rh antibodies in his/her serum from early infancy.

Accepted Answer

A) True 
 B)False

Question 13

An effective test to determine whether an individual is allergic to a specific substance is to

Accepted Answer

A)  test for the allergen in the blood. 
B)  test for levels of IgE specific for the allergen. 
C)  test for high levels of IgG in the serum. 
D)  inject high levels of the allergen so see if the patient goes into anaphylactic shock. 
A)  test for the allergen in the blood. 
B)  test for levels of IgE specific for the allergen. 
C)  test for high levels of IgG in the serum. 
D)  inject high levels of the allergen so see if the patient goes into anaphylactic shock.

Question 14

A person who produces anti-A and anti-B serum antibodies will have blood type ______.

Accepted Answer

A)  Rh 
B)  A 
C)  AB 
D)  O 
E)  B 
A)  Rh 
B)  A 
C)  AB 
D)  O 
E)  B

Question 15

Serum sickness and the Arthus reaction are both type III hypersensitivities,but they differ in that

Accepted Answer

A)  serum sickness is a systemic reaction to an injected therapy, whereas the Arthus reaction remains localized to the injection site. 
B)  serum sickness is an infection in the blood serum, whereas the Arthus reaction is a swelling in the joints. 
C)  serum sickness is vomiting and diarrhea in response to animal serum, whereas the Arthus reaction causes arthritis. 
D)  serum sickness is a localized reaction to an injected therapy, whereas the Arthus reaction is systemic. 
A)  serum sickness is a systemic reaction to an injected therapy, whereas the Arthus reaction remains localized to the injection site. 
B)  serum sickness is an infection in the blood serum, whereas the Arthus reaction is a swelling in the joints. 
C)  serum sickness is vomiting and diarrhea in response to animal serum, whereas the Arthus reaction causes arthritis. 
D)  serum sickness is a localized reaction to an injected therapy, whereas the Arthus reaction is systemic.

Question 16

You were out in the garage going through boxes when you were bitten by an a spider.You tell the doctor that the spider was tiny and black,causing the doctor to think perhaps that it was a black widow spider The doctor gives you an injection of antibody to the spider venom to give you immediate protection.The antibody is produced in horses by injecting them with small doses of the spider venom,causing the horse's immune system to make large amounts of specific antibody to the antigen.The horse serum is then purified before being given to humans.
A. a Staphylococcus infection related to the spider bite.
B. serum sickness.
C. a delayed type hypersensitivity mediated by cytotoxic T cells along with helper T cells.
D. Arthus reaction.
E. anaphylactic shock.

Accepted Answer

A week later,you notice a red rash sprea

Question 17

What can be a consequence of a genetic deficiency in B-cell survival and maturity?

Accepted Answer

A)  Graft versus host disease 
B)  Formation of autoantibodies 
C)  Hypogammaglobulinemia 
D)  Host rejection of graft 
A)  Graft versus host disease 
B)  Formation of autoantibodies 
C)  Hypogammaglobulinemia 
D)  Host rejection of graft

Question 18

Autoantibodies cause tissue injury in all of the following diseases except

Accepted Answer

A)  multiple sclerosis. 
B)  tuberculin reaction. 
C)  rheumatoid arthritis. 
D)  myasthenia gravis. 
E)  Graves'disease. 
A)  multiple sclerosis. 
B)  tuberculin reaction. 
C)  rheumatoid arthritis. 
D)  myasthenia gravis. 
E)  Graves'disease.

Question 19

Which of the following is not a possible outcome of a type I hypersensitivity reaction?

Accepted Answer

A)  Diarrhea 
B)  Rashes 
C)  Contact dermatitis 
D)  Sneezing 
E)  Rhinitis 
A)  Diarrhea 
B)  Rashes 
C)  Contact dermatitis 
D)  Sneezing 
E)  Rhinitis

Question 20

Which of the following is not true of type III hypersensitivity?

Accepted Answer

A)  The Arthus reaction is a local response. 
B)  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues. 
C)  It involves an immune complex reaction. 
D)  Serum sickness is a systemic response. 
E)  It involves production of IgE antibodies. 
A)  The Arthus reaction is a local response. 
B)  Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues. 
C)  It involves an immune complex reaction. 
D)  Serum sickness is a systemic response. 
E)  It involves production of IgE antibodies.

Exam 16: Disorders in Immunity

Autoimmune diseases and immunodeficiencies are studied and treated by immunopathologists.

The major category(ies)of hypersensitivity(ies)that typically involve(s)a B-cell immunoglobulin response include(s)

Myasthenia gravis disease arises from the production of autoantibodies against

Allergic reactions to penicillins are considered a(n)_____ hypersensitivity.

A viral infection can lead to the development of type I diabetes.

A person with O type blood

Bee sting venom is considered to be which type of allergen?

Before a type II hypersensitivity can proceed,three immune components must be in place: complement,IgG,and IgM.

Autoimmunity is typically due to

Food allergies include gastrointestinal symptoms and often hives.

Which of the following is not a target for immune complex deposition?

A person who is Rh- will have anti-Rh antibodies in his/her serum from early infancy.

An effective test to determine whether an individual is allergic to a specific substance is to

A person who produces anti-A and anti-B serum antibodies will have blood type ______.

Serum sickness and the Arthus reaction are both type III hypersensitivities,but they differ in that

What can be a consequence of a genetic deficiency in B-cell survival and maturity?

Autoantibodies cause tissue injury in all of the following diseases except

Which of the following is not a possible outcome of a type I hypersensitivity reaction?

Which of the following is not true of type III hypersensitivity?

The Main Themes of Microbiology

The Chemistry of Biology

Tools of the Laboratory: Methods for the Culturing of Microscopic Analysis of Microorganisms

Bacteria and Archaea

Eukaryotic Cells and Microorganisms

An Introduction to the Viruses

Host Defenses II: Specific Immunity and Immunization

Microbial Metabolism: The Chemical Crossroads of Life

Microbial Genetics

Genetic Engineering and Recombinant Dna

Physical and Chemical Control of Microbes

Antimicrobial Treatment

Microbe-Human Interactions: Health and Disease

Host Defenses I: Overview and Nonspecific Defenses

Host Defenses II: Specific Immunity and Immunization

Diagnosing Infections

Infectious Diseases Affecting the Skin and Eyes

Infectious Diseases Affecting the Nervous System

Infectious Diseases Affecting the Cardiovascular and Lymphatic Systems

Infectious Diseases Affecting the Respiratory System

Infectious Diseases Affecting the Gastrointestinal Tract

Infectious Diseases Affecting the Genitourinary System

Microbes and the Environment

Applied Microbiology and Food and Water Safety

Filters

A person who is Rh^- will have anti-Rh antibodies in his/her serum from early infancy.