Question 1

Unequal crossing over results in

Accepted Answer

A) an exchange between nonhomologous chromosomes. 
B) a loss of genetic material. 
C) a repair of UV-induced damage. 
D) a production of eggs containing Y chromosomes. 
E) a creation of deletions and duplications. 
A) an exchange between nonhomologous chromosomes. 
B) a loss of genetic material. 
C) a repair of UV-induced damage. 
D) a production of eggs containing Y chromosomes. 
E) a creation of deletions and duplications.

Question 2

Indicate the false statement regarding amino acids.

Accepted Answer

A) Every amino acid contains a carboxyl group. 
B) The side chain or R group differs for each amino acid. 
C) Amino acids are joined together by peptide bonds. 
D) The end of the polypeptide termed the N terminus contains a free amino group. 
E) All the choices are correct. 
A) Every amino acid contains a carboxyl group. 
B) The side chain or R group differs for each amino acid. 
C) Amino acids are joined together by peptide bonds. 
D) The end of the polypeptide termed the N terminus contains a free amino group. 
E) All the choices are correct.

Question 3

How many progeny phage are released when a single E.coli cell is lysed by phage T4?

Accepted Answer

A)  between 1 and 10 
B)  between 10 and 100 
C)  between 100 and 1,000 
D)  about 10,000 
E)  about 100,000 
A)  between 1 and 10 
B)  between 10 and 100 
C)  between 100 and 1,000 
D)  about 10,000 
E)  about 100,000

Question 4

The hydrolysis of a purine base from the deoxyribose-phosphate backbone is called

Accepted Answer

A) depurination. 
B) deamination. 
C) replica plating. 
D) excision repair. 
E) deletion. 
A) depurination. 
B) deamination. 
C) replica plating. 
D) excision repair. 
E) deletion.

Question 5

Choose the statement that best distinguishes a complementation test and a recombination analysis when examining mutations in phage.

Accepted Answer

A) Both tests require two different mutations. 
B) Recombination can only occur between two genes. 
C) Complementation results can be seen immediately, recombination requires a second infection. 
D) Recombination results can be seen immediately, complementation requires a second infection. 
E) Recombination can distinguish one gene with two alleles from two different genes. 
A) Both tests require two different mutations. 
B) Recombination can only occur between two genes. 
C) Complementation results can be seen immediately, recombination requires a second infection. 
D) Recombination results can be seen immediately, complementation requires a second infection. 
E) Recombination can distinguish one gene with two alleles from two different genes.

Question 6

The structure of a polypeptide that is characterized by a three dimensional shape with a characteristic geometry at local regions maintained by hydrogen bonds is

Accepted Answer

A) primary structure. 
B) secondary structure. 
C) tertiary structure. 
D) quaternary structure. 
E) both tertiary and quaternary structures. 
A) primary structure. 
B) secondary structure. 
C) tertiary structure. 
D) quaternary structure. 
E) both tertiary and quaternary structures.

Question 7

Assume that a wild-type sequence is 5'AGCCTAC3'.Indicate the sequence that might be produced by a transversion.

Accepted Answer

A) 5'AGTCTAC3' 
B) 5'AGCCGCCGCCGCCTAC3' 
C) 5'AGCCCAC3' 
D) 5'ATCCTAC3' 
E) 5'AGCCTGC3' 
A) 5'AGTCTAC3' 
B) 5'AGCCGCCGCCGCCTAC3' 
C) 5'AGCCCAC3' 
D) 5'ATCCTAC3' 
E) 5'AGCCTGC3'

Question 8

A heritable change in DNA base sequence is called a

Accepted Answer

A) forward mutation. 
B) reversion. 
C) substitution. 
D) deletion. 
E) mutation 
A) forward mutation. 
B) reversion. 
C) substitution. 
D) deletion. 
E) mutation

Question 9

In the Luria Delbruck fluctuation experiment, the bacteria + phage plates showed

Accepted Answer

A) all plates had some resistant colonies, some had very many. 
B) some plates had no resistant colonies, a few plates had very many resistant colonies. 
C) all plates had the same number of resistant colonies. 
D) some plates had no resistant colonies; the plates that had resistant colonies all had the same number of resistant colonies. 
E) phage caused mutations to occur in some of the plates but not in others 
A) all plates had some resistant colonies, some had very many. 
B) some plates had no resistant colonies, a few plates had very many resistant colonies. 
C) all plates had the same number of resistant colonies. 
D) some plates had no resistant colonies; the plates that had resistant colonies all had the same number of resistant colonies. 
E) phage caused mutations to occur in some of the plates but not in others

Question 10

Indicate the false statement regarding amino acids.

Accepted Answer

A) Several amino acids linked together are termed an oligopeptide. 
B) Amino acids are linked by peptide bonds that join two amino groups together. 
C) The C terminus of a polypeptide chain contains a free carboxylic acid group. 
D) Two amino acids joined together are termed a dipeptide. 
E) All the choices are correct. 
A) Several amino acids linked together are termed an oligopeptide. 
B) Amino acids are linked by peptide bonds that join two amino groups together. 
C) The C terminus of a polypeptide chain contains a free carboxylic acid group. 
D) Two amino acids joined together are termed a dipeptide. 
E) All the choices are correct.

Question 11

A complementation group is a group of mutations

Accepted Answer

A) that produce the same phenotype. 
B) that are in the same gene and complement each other. 
C) that are in the same gene and do not complement each other. 
D) in two different genes that complement each other. 
E) in two different genes that do not complement each other. 
A) that produce the same phenotype. 
B) that are in the same gene and complement each other. 
C) that are in the same gene and do not complement each other. 
D) in two different genes that complement each other. 
E) in two different genes that do not complement each other.

Question 12

Choose the interaction listed below that is not involved in maintaining tertiary structure in protein molecules.

Accepted Answer

A) covalent bond 
B) hydrogen bond 
C) hydrophobic/hydrophilic interactions 
D) ionic interactions 
E) All of the choices may be involved in maintaining protein tertiary structure. 
A) covalent bond 
B) hydrogen bond 
C) hydrophobic/hydrophilic interactions 
D) ionic interactions 
E) All of the choices may be involved in maintaining protein tertiary structure.

Question 13

The genetic condition Xeroderma pigmentosum, which can lead to skin cancer, results from

Accepted Answer

A) inability to correct UV induced dimers 
B) inability to process phenylalanine. 
C) inability to produce functional hemoglobin. 
D) inability to correct transitions 
E) breaks in the X chromosome 
A) inability to correct UV induced dimers 
B) inability to process phenylalanine. 
C) inability to produce functional hemoglobin. 
D) inability to correct transitions 
E) breaks in the X chromosome

Question 14

Excision repair corrects DNA by

Accepted Answer

A) removing a double-stranded fragment of damaged DNA. 
B) detecting, removing, and replacing damaged or incorrect nucleotides in a single strand of DNA. 
C) excising the incorrect base from a nucleotide 
D) removing extraneous groups such as methyl or oxygen added by mutagens. 
E) correcting A=T to C=G transitions. 
A) removing a double-stranded fragment of damaged DNA. 
B) detecting, removing, and replacing damaged or incorrect nucleotides in a single strand of DNA. 
C) excising the incorrect base from a nucleotide 
D) removing extraneous groups such as methyl or oxygen added by mutagens. 
E) correcting A=T to C=G transitions.

Question 15

Genes on the X chromosome of mammals and Drosophila are particularly suitable for genetic study because

Accepted Answer

A) males have only one X and most genes behave as haploids. 
B) females have only one X and most genes behave as haploids. 
C) the X chromosome is large and many more genes are located there. 
D) when present as Barr bodies they are exposed for electron microscopic examination. 
E) they behave as diploids in females. 
A) males have only one X and most genes behave as haploids. 
B) females have only one X and most genes behave as haploids. 
C) the X chromosome is large and many more genes are located there. 
D) when present as Barr bodies they are exposed for electron microscopic examination. 
E) they behave as diploids in females.

Question 16

Base analogs differ from other classes of mutagen in that they

Accepted Answer

A) only alter bases 
B) can only cause transversions 
C) only work during DNA replication or repair. 
D) can only cause forward mutations, nor reversions. 
E) will not function in bacterial cells. 
A) only alter bases 
B) can only cause transversions 
C) only work during DNA replication or repair. 
D) can only cause forward mutations, nor reversions. 
E) will not function in bacterial cells.

Question 17

The heritable disorder Fragile X syndrome, a major cause of mental retardation, is caused by

Accepted Answer

A) production of enzymes that break the phosphate backbone. 
B) UV light. 
C) X-rays. 
D) presence of an extra X chromosome in the sperm or egg 
E) duplication of multiple three-nucleotide repeats. 
A) production of enzymes that break the phosphate backbone. 
B) UV light. 
C) X-rays. 
D) presence of an extra X chromosome in the sperm or egg 
E) duplication of multiple three-nucleotide repeats.

Question 18

UV light is a mutagen that can cause

Accepted Answer

A) depurination. 
B) deamination. 
C) alkylation. 
D) thymine dimers 
E) oxidation. 
A) depurination. 
B) deamination. 
C) alkylation. 
D) thymine dimers 
E) oxidation.

Question 19

The results of the Luria Delbruck fluctuation experiment indicated that

Accepted Answer

A) bacteria are naturally resistant to phage. 
B) a low level of any bacterial population is naturally resistant to phage. 
C) bacteria become resistant to phage by mutation when exposed to phage. 
D) bacteria become resistant to phage by random spontaneous mutation. 
E) the phage mutate to produce large plaques with sharp edges. 
A) bacteria are naturally resistant to phage. 
B) a low level of any bacterial population is naturally resistant to phage. 
C) bacteria become resistant to phage by mutation when exposed to phage. 
D) bacteria become resistant to phage by random spontaneous mutation. 
E) the phage mutate to produce large plaques with sharp edges.

Question 20

The condition sickle cell anemia is due to

Accepted Answer

A) the insertion of an amino acid. 
B) the deletion of an amino acid. 
C) substitution of an amino acid. 
D) failure to synthesize a hemoglobin molecule. 
E) unequal recombination resulting in the deletion of the $\beta$-chain hemoglobin gene. 
A) the insertion of an amino acid. 
B) the deletion of an amino acid. 
C) substitution of an amino acid. 
D) failure to synthesize a hemoglobin molecule. 
E) unequal recombination resulting in the deletion of the $\beta$-chain hemoglobin gene.

Exam 7: Anatomy and Function of a Gene: Dissection Through Mutation

Unequal crossing over results in

Indicate the false statement regarding amino acids.

How many progeny phage are released when a single E.coli cell is lysed by phage T4?

The hydrolysis of a purine base from the deoxyribose-phosphate backbone is called

Choose the statement that best distinguishes a complementation test and a recombination analysis when examining mutations in phage.

The structure of a polypeptide that is characterized by a three dimensional shape with a characteristic geometry at local regions maintained by hydrogen bonds is

Assume that a wild-type sequence is 5'AGCCTAC3'.Indicate the sequence that might be produced by a transversion.

A heritable change in DNA base sequence is called a

In the Luria Delbruck fluctuation experiment, the bacteria + phage plates showed

Indicate the false statement regarding amino acids.

A complementation group is a group of mutations

Choose the interaction listed below that is not involved in maintaining tertiary structure in protein molecules.

The genetic condition Xeroderma pigmentosum, which can lead to skin cancer, results from

Excision repair corrects DNA by

Genes on the X chromosome of mammals and Drosophila are particularly suitable for genetic study because

Base analogs differ from other classes of mutagen in that they

The heritable disorder Fragile X syndrome, a major cause of mental retardation, is caused by

UV light is a mutagen that can cause

The results of the Luria Delbruck fluctuation experiment indicated that

The condition sickle cell anemia is due to

Genetics: The Study of Biological Information

Mendels Principles of Heredity

Extensions to Mendels Laws

The Chromosome Theory of Inheritance

Linkage, Recombination, and the Mapping of Genes on Chromosomes

DNA Structure, Replication, and Recombination

Gene Expression: The Flow of Information From DNA to RNA to Protein

Digital Analysis of Genomes

Analyzing Genomic Information

The Eukaryotic Chromosome

Chromosomal Rearrangements and Changes in Chromosome Number

Bacterial Genetics

Organellar Inheritance

Gene Regulation in Prokaryotes

Gene Regulation in Eukaryotes

Manipulating the Genomes of Eukaryotes

The Genetic Analysis of Development

The Genetics of Cancer

Variation and Selection in Populations

Genetics of Complex Traits

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