Exam 5: Linkage, Recombination, and the Mapping of Genes on Chromosomes

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In an ordered octad, every spore is adjacent to at least one spore that is genetically identical to itself.

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The locus B on the X chromosome of a malaria-carrying mosquito shows a 49% recombination rate with respect to the locus M.Since a recombination rate of 50% is essentially indistinguishable from independent assortment, you might be tempted to look for a locus that falls between B and M.Before you decide to do all that work, you run a chi-square test to determine the p value of your experiment.Which of the following p values would be most likely to tell you that you should accept the conclusion that locus B and locus M are, indeed, 49 mu apart and that another locus is not necessary?

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A woman whose mother is colorblind and whose father has hemophilia A is pregnant with a boy and what is the probability that the baby will have normal vision and blood clotting?

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Tetrad analysis shows that crossing over occurs at the four-strand stage (i.e., after replication) because, when two genes are linked,

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What is the p value from this test? (Pick the most accurate choice.)

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Twin spotting provides evidence of what genetic event?

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Two genes are considered linked when F2 progeny more commonly show the recombinant genotype.

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Which of the following linkage maps correctly shows the order and distance between the y, f, and v genes?

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Genes that are not syntenic are not linked.

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Which of the following processes can generate recombinant gametes?

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ws; ws; ws+; ws+; ws+; ws+; ws; ws

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Chiasmata can be seen through a light microscope and are sites of recombination.

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The diploid garden pea plant has 14 chromosomes.The haploid fungus Neurospora crassa has 7 chromosomes.Neither organism has separate male and female individuals.Therefore, the number of linkage groups in these two organisms is:

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his4/trp1; his4/trp1; HIS4/TRP1;HIS4/TRP

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HIS4/trp1; HIS4/trp1; his4/TRP1; his4/TRP1

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Fungi that produce tetrads typically grow as haploids but can undergo sexual reproduction by combining different mating types.

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Given this data, which of the following is the most accurate range within which the p value falls, and what can be concluded?

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If the map distance between genes A and B is 10 map units and the map distance between genes B and C is 25 map units, what is the map distance between genes A and C?

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ws; ws; ws; ws; ws+; ws+; ws+; ws+

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Some of the larger human chromosomes typically contain multiple chiasmata during meiotic prophase.If you were to carefully study the distribution of these chiasmata, what would you find?

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