Question 1

Which of the following catalyzes the synthesis of ribosomal RNA in eukaryotes?

Accepted Answer

A) RNA polymerase I 
B) RNA polymerase II 
C) RNA polymerase III 
D) Both RNA polymerase I and II 
E) Both RNA polymerase I and III 
A) RNA polymerase I 
B) RNA polymerase II 
C) RNA polymerase III 
D) Both RNA polymerase I and II 
E) Both RNA polymerase I and III

Question 2

What is the difference between an intervening sequence and an untranslated region in a eukaryotic mRNA?

Accepted Answer

Untranslated regions (UTRs)are found on

Question 3

What was the significance of the 1978 finding by Philip Leder's research group that the 0.7 kb β-globin mRNA is not colinear with the gene that encodes it,but the nuclear 1.5 kb pre-mRNA is?

Accepted Answer

This meant that the β-globin contains an

Question 4

Describe the structure and organization of the rDNA repeat unit in eukaryotes.

Accepted Answer

The rDNA repeat unit exists in tandem ar

Question 5

In eukaryotes,what is the difference between promoter proximal elements in "housekeeping genes" vs.cell-specific genes,and how does this relate to gene expression?

Accepted Answer

In genes that are expressed in all cell

Question 6

What would be the advantage of having multiple sigma factors that each could be produced under different stress conditions in E.coli?

Accepted Answer

Different sigma factors recognize differ

Question 7

What is the advantage of having a promoter sequence upstream of a coding sequence?

Accepted Answer

The promoter ensures that the

Question 8

Self-cleaving RNAs that function catalytically are called

Accepted Answer

A) snRNPs. 
B) snRNAs. 
C) ribozymes. 
D) ribosomes. 
E) spliceosomes. 
A) snRNPs. 
B) snRNAs. 
C) ribozymes. 
D) ribosomes. 
E) spliceosomes.

Question 9

The poly(A)tail of an mRNA

Accepted Answer

A) helps transport the pre-mRNA to the cytoplasm. 
B) keeps the coding sequences from being degraded. 
C) is added without an RNA template. 
D) is important in initiation of translation. 
E) is removed from an mRNA after its maturation. 
A) helps transport the pre-mRNA to the cytoplasm. 
B) keeps the coding sequences from being degraded. 
C) is added without an RNA template. 
D) is important in initiation of translation. 
E) is removed from an mRNA after its maturation.

Question 10

All genes encode proteins.

Accepted Answer

A) True 
 B)False

Question 11

What is the function of the inverted repeat in the termination sequence of a rho-independent terminator? What would happen if a mutation occurred in this region?

Accepted Answer

RNA polymerase transcribes the inverted

Question 12

What are the functions of the 5' cap and poly(A)tail of mature mRNAs in eukaryotes?

Accepted Answer

Both protect the mRNA from degradation b

Question 13

How does the rate of initiation of transcription relate to the similarity of the promoter region to the consensus sequence?

Accepted Answer

The ability of the sigma factor of the R

Question 14

During transcription,the synthesis of the mRNA strand proceeds in which direction?

Accepted Answer

A) 5' to 3' only 
B) 3' to 5' only 
C) Both 5' to 3' and 3' to 5' 
D) Either 5' to 3' or 3' to 5' 
E) First 5' to 3',and then 3' to 5' 
A) 5' to 3' only 
B) 3' to 5' only 
C) Both 5' to 3' and 3' to 5' 
D) Either 5' to 3' or 3' to 5' 
E) First 5' to 3',and then 3' to 5'

Question 15

Which of the following is not found in a eukaryotic promoter?

Accepted Answer

A) -10 box 
B) TATA box 
C) GC box 
D) CAAT box 
E) None of these 
A) -10 box 
B) TATA box 
C) GC box 
D) CAAT box 
E) None of these

Question 16

What are the three regions of a prokaryotic gene?

Accepted Answer

A promoter region,an

Question 17

Before a prokaryotic mRNA can be translated,it must be modified by the addition of a polyA tail.

Accepted Answer

A) True 
 B)False

Question 18

Match between columns
                        Premises: rRNA
snRNA
mRNA
GTF
tRNA

Accepted Answer

The Answer of Encodes the amino acid sequence of a is...

Question 19

During the initiation step of transcription,which molecule binds the promoter region of a DNA molecule?

Accepted Answer

A) DNA polymerase 
B) Reverse transcriptase 
C) RNA polymerase 
D) DNA primase 
E) Topoisomerase 
A) DNA polymerase 
B) Reverse transcriptase 
C) RNA polymerase 
D) DNA primase 
E) Topoisomerase

Question 20

The process by which genetic information is transferred from DNA to RNA is called

Accepted Answer

A) replication. 
B) transcription. 
C) translation. 
D) transversion. 
E) transformation. 
A) replication. 
B) transcription. 
C) translation. 
D) transversion. 
E) transformation.

Exam 5: Gene Expression: Transcription

Which of the following catalyzes the synthesis of ribosomal RNA in eukaryotes?

What is the difference between an intervening sequence and an untranslated region in a eukaryotic mRNA?

What was the significance of the 1978 finding by Philip Leder's research group that the 0.7 kb β-globin mRNA is not colinear with the gene that encodes it,but the nuclear 1.5 kb pre-mRNA is?

Describe the structure and organization of the rDNA repeat unit in eukaryotes.

In eukaryotes,what is the difference between promoter proximal elements in "housekeeping genes" vs.cell-specific genes,and how does this relate to gene expression?

What would be the advantage of having multiple sigma factors that each could be produced under different stress conditions in E.coli?

What is the advantage of having a promoter sequence upstream of a coding sequence?

Self-cleaving RNAs that function catalytically are called

The poly(A)tail of an mRNA

All genes encode proteins.

What is the function of the inverted repeat in the termination sequence of a rho-independent terminator? What would happen if a mutation occurred in this region?

What are the functions of the 5' cap and poly(A)tail of mature mRNAs in eukaryotes?

How does the rate of initiation of transcription relate to the similarity of the promoter region to the consensus sequence?

During transcription,the synthesis of the mRNA strand proceeds in which direction?

Which of the following is not found in a eukaryotic promoter?

What are the three regions of a prokaryotic gene?

Before a prokaryotic mRNA can be translated,it must be modified by the addition of a polyA tail.

During the initiation step of transcription,which molecule binds the promoter region of a DNA molecule?

The process by which genetic information is transferred from DNA to RNA is called

Genetics: An Introduction

DNA: The Genetic Material

DNA Replication

Gene Function

Gene Expression: Translation

Dna Mutation, DNA Repair, and Transposable Elements

Genomics: The Mapping and Sequencing of Genomes

Functional and Comparative Genomics

Recombinant DNA Technology

Mendelian Genetics

Chromosomal Basis of Inheritance

Extensions of and Deviations From Mendelian Genetic Principles

Genetic Mapping in Eukaryotes

Genetics of Bacteria and Bacteriophages

Variations in Chromosome Structure and Number

Regulation of Gene Expression in Bacteria and Bacteriophages

Regulation of Gene Expression in Eukaryotes

Genetic Analysis of Development

Genetics of Cancer

Population Genetics

Quantitative Genetics

Molecular Evolution

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