Exam 18: Regulation of Gene Expression in Eukaryotes

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Unlike prokaryotes,most gene regulation in eukaryotes

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Steriod hormones are effector molecules.

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Plants produce steroids called phytosterols,which have various functions in plant physiology.Some phytosterols are thought to have a defensive function,however,specifically in repelling insect herbivores.How might plant-derived steroids help protect plants from insect attack?

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What would happen developmentally if a zygote with XY sex chromosome karyotype had a defective testosterone receptor?

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Several common protein structural motifs are now known to be involved in DNA recognition and binding.What are these,and how would researchers use genomic data to help figure out if new candidate genes encode such DNA-binding proteins?

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Imprinting is implicated in Prader-Willi and Angelman syndromes.

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Embryonic development is orchestrated by a cascading series of genes,the expression of many of which are controlled in time and space by transcription factors and effector molecules of various kinds.But what controls the expression of the first regulatory genes to be transcribed in the newly fertilized zygote?

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Control of transcription initiation of eukaryotic protein-coding genes involves

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longer poly(A)tails on mRNAs are associated with less translational activity.

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Hormones can be considered

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With respect to genetics,URS stands for

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Proteins that are encoded by the same gene but differ in structure and function are the product of alternative splicing in pre-mRNA processing.Such protein variants are termed

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What are some advantages and disadvantages of arranging gene clusters into operons?

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Explain how combinatorial gene regulation permits regulation of a large diversity of genes with relatively few regulatory proteins.

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Insect growth and metamorphosis is controlled by the steroid hormones ecdysone and juvenile hormone (JH).In insects like butterflies and moths that have a distinct larval (juvenile)and adult stage,the relative amount of JH determines whether the insect molts to the next juvenile stage or switches to become an adult.Can you think of a way to use this hormonal system to control caterpillar agricultural pests?

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Steroid and peptide hormone receptors are typically cytoplasmic.

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mRNA regulation can be achieved at the level of

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Describe how siRNA functions in regulation of expression and how this can be used as a tool in genetic research.

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Gene silencing is a form of regulation controlled by repressor proteins.

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HREs are

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