Exam 4: Principles of Neural and Hormonal Communication

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Describe the currents associated with EPSPs and IPSPs.

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At an excitatory synapse the binding of neurotransmitter to a receptor opens both Na+ and K+ channels. The electrochemical gradient favors the movement of Na+ into the cell, resulting in small depolarization or an EPSP. In an inhibitory synapse the binding of neurotransmitter to a receptor opens both K+ and Cl- channels. Cl- enters the cell, K+ leaves the cell, and the cell becomes hyperpolarized producing an IPSP.

Which of the classes of hormones triggers the synthesis of new intracellular proteins within the target cell?

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E

Use the answer code to answer the questions in this section: -The change in potassium permebaility hat occur at the peak of an action potential.

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C

The axon hillock occurs in between the cell body and axon of a neuron.

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Indicate whether the membrane is more permeable to K+ or to Na+ or is equally permeable to these ions under the stated conditions by writing the appropriate letter in the blank using the following answer code: -at resting potential

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Indicate which characteristic applies to classical neurotransmitters and neuropeptides using the following answer code: -small: one amino acid or similar chemical

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____________________ is the hindrance to electrical charge movement.

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Nerve and muscle cells establish resting membrane potentials.

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____________________ along axons reduces resistance and, hence, increases impulse velocity.

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Most endocrine control systems involve ____________________ and hormonal components.

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Each letter is used only once. -synapse

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Indicate whether an excitatory or inhibitory synapse is being described by filling in the blank using the following answer code: -increased PCl- of the subsynaptic membrane

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   The accompanying figure relates to neurotransmitter secretion. Match the steps highlighted in the figure (steps 1-5) with the statements using the letter key below. -Neurotransmitter is released by exocytosis The accompanying figure relates to neurotransmitter secretion. Match the steps highlighted in the figure (steps 1-5) with the statements using the letter key below. -Neurotransmitter is released by exocytosis

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The majority of hormones falls into the class of ____________________.

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A drug that blocks the reuptake of a NT in a synapse:

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Each letter is used only once. -axon

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The ____________________hormones are derived from tyrosine.

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Indicate which characteristic applies to classical neurotransmitters and neuropeptides using the following answer code: -usually function as neuromodulators

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MATCHING: ART MATCHING: ART     The following questions refer to the accompanying diagram of an action potential. Segments of the action potential are labeled A-D. Match the letters to the corresponding statements below. -Pre-threshold stage The following questions refer to the accompanying diagram of an action potential. Segments of the action potential are labeled A-D. Match the letters to the corresponding statements below. -Pre-threshold stage

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All amine hormones are hydrophilic.

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