Exam 21: Serologic and Molecular Detection of Bacterial Infections

Which of the following may characterize the disease process in syphilis?

Which of the following is a cause of a biological false-negative in the screening tests for syphilis?

Which of the following is a confirmatory test for syphilis?

A patient is suspected of having latent syphilis.Which set of test results for RPR,MHA-TP,and CSF-VDRL best confirms this diagnosis?

Which best describes the antibody known as reagin?

The RPR and VDRL are similar in which of the following ways? RPR and VDRL are both:

Patient serum is mixed with sheep red blood cells that have been sensitized with Treponema pallidum antigens as well as with unsensitized red blood cells in a separate well.Agglutination was observed in the well with sensitized red blood cells and not in the well with unsensitized red blood cells.What is the interpretation of these results?

A laboratory test that is used to confirm syphilis and detects specific treponemal antibodies is:

Which of the following is a cause of a biological false-positive in the screening assays for syphilis?

A new technologist is busy one night and has to perform an RPR on a serum sample.He does not calibrate the needle delivering the antigen and the needle is delivering a larger volume of antigen than it is supposed to.What kind of error can this cause on the test result?

A patient presents with a painless genital ulcer.The patient is then diagnosed as having syphilis.In what stage of syphilis is the patient?

Lab results on a patient indicated a positive RPR and a negative FTA.The patient had no obvious sore,rash,or other symptoms.What is the most likely cause of these results?

A patient is diagnosed with syphilis.Which of the following laboratory tests can be used to monitor the effectiveness of therapy in this patient?

At which stage of syphilis is the RPR the most sensitive?

A patient has a reactive RPR at a titer of 1:128 and a reactive MHA-TP.What does this indicate for the patient?

Which best describes the antibody called reagin found in syphilis?

Lyme disease is caused by:

In an indirect fluorescent immunoassay such as the FTA confirmatory test for syphilis,all of the following are true EXCEPT:

RPR stands for

A 32-year-old heterosexual male presents to the physician with a 3-day history of multiple skin lesions located all over his body and on his mucous membranes.He hasn't felt well and has a low-grade fever.The patient cuts down trees in Massachusetts for a living.He is single,has had multiple sex partners,and does not use condoms.Here are the results of his laboratory tests: rapid plasma reagin = reactive 1:128; Treponema pallidum-particle agglutination assay = reactive; Borrelia burgdorferi IgM = < 1:8; Rickettsia rickettsii IgM < 1:8.This patient has: