Question 1

Coombs' reagent is used for what purpose?

Accepted Answer

A)  to link small antigens on patient red cells 
B)  to enhance agglutination with IgG coated red blood cells 
C)  to enhance agglutination with IgM coated red blood cells 
D)  to cause a precipitation reaction with small amounts of antibody 
A)  to link small antigens on patient red cells 
B)  to enhance agglutination with IgG coated red blood cells 
C)  to enhance agglutination with IgM coated red blood cells 
D)  to cause a precipitation reaction with small amounts of antibody B

Question 2

Which antibody class may require the use of an enhancement technique to visualize the reaction?

Accepted Answer

A)  IgM 
B)  IgG 
C)  IgA 
D)  IgE 
A)  IgM 
B)  IgG 
C)  IgA 
D)  IgE B

Question 3

What would be the best test to determine evidence of hemolytic disease of the newborn?

Accepted Answer

A)  direct antiglobulin testing 
B)  passive agglutination 
C)  coagglutination testing 
D)  indirect antiglobulin testing 
A)  direct antiglobulin testing 
B)  passive agglutination 
C)  coagglutination testing 
D)  indirect antiglobulin testing D

Question 4

The process by which particulate antigens such as cells aggregate to form larger complexes when specific antibody is present is called:

Accepted Answer

A)  sensitization 
B)  precipitation 
C)  agglutination 
D)  flocculation 
A)  sensitization 
B)  precipitation 
C)  agglutination 
D)  flocculation

Question 5

In performing blood typing using the tube method,if the red cell button is not resuspended properly,what are the most likely results?

Accepted Answer

A)  false-positive 
B)  false-negative 
C)  doesn't affect the results 
D)  makes the reaction weaker 
A)  false-positive 
B)  false-negative 
C)  doesn't affect the results 
D)  makes the reaction weaker

Question 6

When carrier particles are coated with an antigen that is not normally found on them,this is known as:

Accepted Answer

A)  direct agglutination 
B)  passive agglutination 
C)  reverse passive agglutination 
D)  hemagglutination 
A)  direct agglutination 
B)  passive agglutination 
C)  reverse passive agglutination 
D)  hemagglutination

Question 7

When a patient's red blood cells combine with anti-A typing serum to produce a positive result,this reaction is known as:

Accepted Answer

A)  passive agglutination 
B)  reverse passive agglutination 
C)  hemagglutination 
D)  flocculation 
A)  passive agglutination 
B)  reverse passive agglutination 
C)  hemagglutination 
D)  flocculation

Question 8

A serological test that uses red blood cells coated with exogenous antigens such as bacterial polysaccharides as a method to detect patient antibodies against that exogenous antigen is called:

Accepted Answer

A)  latex agglutination 
B)  hemagglutination 
C)  neutralization 
D)  complement fixation 
A)  latex agglutination 
B)  hemagglutination 
C)  neutralization 
D)  complement fixation

Question 9

If a Coombs' test is positive,which of the following is true?

Accepted Answer

A)  Antibody has coated patient red blood cells in vitro. 
B)  Antigen is reacting with patient antibody. 
C)  Antibody has coated patient red blood cells in vivo. 
D)  Antigen has coated patient red blood cells in vivo. 
A)  Antibody has coated patient red blood cells in vitro. 
B)  Antigen is reacting with patient antibody. 
C)  Antibody has coated patient red blood cells in vivo. 
D)  Antigen has coated patient red blood cells in vivo.

Question 10

Which of the following would enhance an agglutination reaction?

Accepted Answer

A)  polyethylene glycol (PEG) 
B)  high ionic strength saline 
C)  running the reaction at 4C 
D)  running the reaction at a high pH 
A)  polyethylene glycol (PEG) 
B)  high ionic strength saline 
C)  running the reaction at 4C 
D)  running the reaction at a high pH

Question 11

A serological reaction is set up in which the antigen is bound to a large carrier,the antibody is soluble,and they bind and form an insoluble complex that is detected macroscopically.What type of assay is described?

Accepted Answer

A)  precipitation 
B)  agglutination 
C)  flocculation 
D)  neutralization 
A)  precipitation 
B)  agglutination 
C)  flocculation 
D)  neutralization

Coombs' reagent is used for what purpose?

Which antibody class may require the use of an enhancement technique to visualize the reaction?

What would be the best test to determine evidence of hemolytic disease of the newborn?

The process by which particulate antigens such as cells aggregate to form larger complexes when specific antibody is present is called:

In performing blood typing using the tube method,if the red cell button is not resuspended properly,what are the most likely results?

When carrier particles are coated with an antigen that is not normally found on them,this is known as:

When a patient's red blood cells combine with anti-A typing serum to produce a positive result,this reaction is known as:

A serological test that uses red blood cells coated with exogenous antigens such as bacterial polysaccharides as a method to detect patient antibodies against that exogenous antigen is called:

If a Coombs' test is positive,which of the following is true?

Which of the following would enhance an agglutination reaction?

A serological reaction is set up in which the antigen is bound to a large carrier,the antibody is soluble,and they bind and form an insoluble complex that is detected macroscopically.What type of assay is described?

Introduction and Natural Immunity

Lymphoid System

Nature of Antigens and Major Histocompatibility Complex

Antibody Structure and Function

Cytokines

Complement System

Safety and Specimen Preparation

Precipitation Reactions

Labeled Immunoassays

Molecular Techniques

Flow Cytometry and Laboratory Automation

Hypersensitivity

Autoimmunity

Immunoproliferative Diseases

Immunodeficiency Disease

Transplantation Immunology

Tumor Immunology

Serologic and Molecular Detection of Bacterial Infections

Serologic and Molecular Detection of Bacterial Infections

Serology of Parasitic and Fungal Infections

Spirochete Diseases

Filters

Exam 9: Agglutination

Coombs' reagent is used for what purpose?

Which antibody class may require the use of an enhancement technique to visualize the reaction?

What would be the best test to determine evidence of hemolytic disease of the newborn?

The process by which particulate antigens such as cells aggregate to form larger complexes when specific antibody is present is called:

In performing blood typing using the tube method,if the red cell button is not resuspended properly,what are the most likely results?

When carrier particles are coated with an antigen that is not normally found on them,this is known as:

When a patient's red blood cells combine with anti-A typing serum to produce a positive result,this reaction is known as:

A serological test that uses red blood cells coated with exogenous antigens such as bacterial polysaccharides as a method to detect patient antibodies against that exogenous antigen is called:

If a Coombs' test is positive,which of the following is true?

Which of the following would enhance an agglutination reaction?

A serological reaction is set up in which the antigen is bound to a large carrier,the antibody is soluble,and they bind and form an insoluble complex that is detected macroscopically.What type of assay is described?

Introduction and Natural Immunity

Lymphoid System

Nature of Antigens and Major Histocompatibility Complex

Antibody Structure and Function

Cytokines

Complement System

Safety and Specimen Preparation

Precipitation Reactions

Labeled Immunoassays

Molecular Techniques

Flow Cytometry and Laboratory Automation

Hypersensitivity

Autoimmunity

Immunoproliferative Diseases

Immunodeficiency Disease

Transplantation Immunology

Tumor Immunology

Serologic and Molecular Detection of Bacterial Infections

Serologic and Molecular Detection of Bacterial Infections

Serology of Parasitic and Fungal Infections

Spirochete Diseases

Filters