Question 1

IL-2 is produced by one cell and the same IL-2 stimulates that same cell.This type of cytokine activity is called:

Accepted Answer

A)  autocrine 
B)  paracrine 
C)  endocrine 
D)  pleotropic 
A)  autocrine 
B)  paracrine 
C)  endocrine 
D)  pleotropic A

Question 2

IL-2 is synthesized by which type of cell and acts on which type of cell?

Accepted Answer

A)  TH1; CTL 
B)  TH2; CTL 
C)  TH2; NK 
D)  TH1; mast cells 
A)  TH1; CTL 
B)  TH2; CTL 
C)  TH2; NK 
D)  TH1; mast cells A

Question 3

IL-3,IL-7,and GM-CSF are all involved in:

Accepted Answer

A)  hematopoiesis 
B)  suppressing inflammation 
C)  macrophage killing 
D)  T cell cytotoxicity 
A)  hematopoiesis 
B)  suppressing inflammation 
C)  macrophage killing 
D)  T cell cytotoxicity A

Question 4

A protein released from a virally infected cell that protects other cells from viral invasion best describes:

Accepted Answer

A)  Il-3 
B)  interferon-alpha 
C)  TNF 
D)  IL-4 
A)  Il-3 
B)  interferon-alpha 
C)  TNF 
D)  IL-4

Question 5

When Il-2 acts on T cells,B cells,and NK cells,this is an example of:

Accepted Answer

A)  redundancy 
B)  pleiotropy 
C)  synergy 
D)  antagonism 
A)  redundancy 
B)  pleiotropy 
C)  synergy 
D)  antagonism

Question 6

Which cells produce interleukin-1?

Accepted Answer

A)  T helper cells 
B)  cytotoxic T cells 
C)  B cells 
D)  macrophages 
A)  T helper cells 
B)  cytotoxic T cells 
C)  B cells 
D)  macrophages

Question 7

When multiple cytokines act on the same cell,by definition they have:

Accepted Answer

A)  pleiotropy 
B)  redundancy 
C)  synergism 
D)  antagonism 
A)  pleiotropy 
B)  redundancy 
C)  synergism 
D)  antagonism

Question 8

IFN-gamma is produced by:

Accepted Answer

A)  B cells 
B)  TH1 cells 
C)  TH2 cells 
D)  macrophages 
A)  B cells 
B)  TH1 cells 
C)  TH2 cells 
D)  macrophages

Question 9

IL-1,IL-6,and tumor necrosis factor-alpha function by:

Accepted Answer

A)  increasing vascular permeability 
B)  increasing acute phase proteins 
C)  acting on the hypothalamus 
D)  promoting migration of inflammatory cells 
E)  all of these 
A)  increasing vascular permeability 
B)  increasing acute phase proteins 
C)  acting on the hypothalamus 
D)  promoting migration of inflammatory cells 
E)  all of these

Question 10

Which cytokine is involved in natural immunity?

Accepted Answer

A)  interleukin-6 
B)  interleukin-2 
C)  interleukin-4 
D)  interleukin-5 
A)  interleukin-6 
B)  interleukin-2 
C)  interleukin-4 
D)  interleukin-5

Question 11

Which of the following cytokines is produced by TH1 cells and is suppressive for TH2 lymphocytes?

Accepted Answer

A)  IL-2 
B)  IL-4 
C)  TGF-beta 
D)  IFN-gamma 
A)  IL-2 
B)  IL-4 
C)  TGF-beta 
D)  IFN-gamma

Question 12

Erythropoietin is classified as which of the following?

Accepted Answer

A)  T-cell regulator 
B)  colony-stimulating factor 
C)  proinflammatory cytokine 
D)  regulator of the acute phase response 
A)  T-cell regulator 
B)  colony-stimulating factor 
C)  proinflammatory cytokine 
D)  regulator of the acute phase response

Question 13

What is the function of TGF-$\beta$?

Accepted Answer

A)  helps in antibody-mediated immunity 
B)  regulates cell growth and differentiation 
C)  inhibits IL-2 
D)  acts as an endogenous pyrogen 
A)  helps in antibody-mediated immunity 
B)  regulates cell growth and differentiation 
C)  inhibits IL-2 
D)  acts as an endogenous pyrogen

Question 14

All of the following are actions of interleukin-1 EXCEPT:

Accepted Answer

A)  increased synthesis of acute phase reactants 
B)  attraction of white cells to the area 
C)  increased production of IgE 
D)  acts as an endogenous pyrogen 
A)  increased synthesis of acute phase reactants 
B)  attraction of white cells to the area 
C)  increased production of IgE 
D)  acts as an endogenous pyrogen

Question 15

Which best describes the nature of interleukin-2?

Accepted Answer

A)  activates T helper cells 
B)  made by macrophages 
C)  causes lysis of tumor cells 
D)  down-regulates the immune response 
A)  activates T helper cells 
B)  made by macrophages 
C)  causes lysis of tumor cells 
D)  down-regulates the immune response

Question 16

The main target of interleukin-3 is:

Accepted Answer

A)  antigen-activated B cells 
B)  antigen-activated T cells 
C)  macrophages 
D)  stem cells 
A)  antigen-activated B cells 
B)  antigen-activated T cells 
C)  macrophages 
D)  stem cells

Question 17

Which of the following can be attributed to interleukin-6 (IL-6)?

Accepted Answer

A)  stimulates red blood cell production 
B)  increases vascular permeability 
C)  inhibits antigen presentation by macrophages 
D)  increases activation of T and B cells 
A)  stimulates red blood cell production 
B)  increases vascular permeability 
C)  inhibits antigen presentation by macrophages 
D)  increases activation of T and B cells

Question 18

The actions of IL-1 and IL-10 are an example of:

Accepted Answer

A)  redundancy 
B)  antagonism 
C)  synergy 
D)  pleiotropy 
A)  redundancy 
B)  antagonism 
C)  synergy 
D)  pleiotropy

Question 19

What is the main function of chemokines?

Accepted Answer

A)  inhibit the immune response 
B)  enhance synthesis of acute phase reactants 
C)  enhance migration of white blood cells 
D)  protect cells from viral invasion. 
A)  inhibit the immune response 
B)  enhance synthesis of acute phase reactants 
C)  enhance migration of white blood cells 
D)  protect cells from viral invasion.

Question 20

IL-4 functions by:

Accepted Answer

A)  inhibiting macrophages 
B)  inducing hematopoiesis 
C)  activating B cells 
D)  activating macrophages 
A)  inhibiting macrophages 
B)  inducing hematopoiesis 
C)  activating B cells 
D)  activating macrophages

Exam 5: Cytokines

IL-2 is produced by one cell and the same IL-2 stimulates that same cell.This type of cytokine activity is called:

IL-2 is synthesized by which type of cell and acts on which type of cell?

IL-3,IL-7,and GM-CSF are all involved in:

A protein released from a virally infected cell that protects other cells from viral invasion best describes:

When Il-2 acts on T cells,B cells,and NK cells,this is an example of:

Which cells produce interleukin-1?

When multiple cytokines act on the same cell,by definition they have:

IFN-gamma is produced by:

IL-1,IL-6,and tumor necrosis factor-alpha function by:

Which cytokine is involved in natural immunity?

Which of the following cytokines is produced by TH1 cells and is suppressive for TH2 lymphocytes?

Erythropoietin is classified as which of the following?

What is the function of TGF- β\betaβ ?

All of the following are actions of interleukin-1 EXCEPT:

Which best describes the nature of interleukin-2?

The main target of interleukin-3 is:

Which of the following can be attributed to interleukin-6 (IL-6)?

The actions of IL-1 and IL-10 are an example of:

What is the main function of chemokines?

IL-4 functions by:

Introduction and Natural Immunity

Lymphoid System

Nature of Antigens and Major Histocompatibility Complex

Antibody Structure and Function

Complement System

Safety and Specimen Preparation

Precipitation Reactions

Agglutination

Labeled Immunoassays

Molecular Techniques

Flow Cytometry and Laboratory Automation

Hypersensitivity

Autoimmunity

Immunoproliferative Diseases

Immunodeficiency Disease

Transplantation Immunology

Tumor Immunology

Serologic and Molecular Detection of Bacterial Infections

Serologic and Molecular Detection of Bacterial Infections

Serology of Parasitic and Fungal Infections

Spirochete Diseases

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What is the function of TGF- $\beta$ ?