Exam 15: Immunoproliferative Diseases

What is the interpretation of the following patient results? (normal values)WBC = 90.0 th/uL (5.0-10.0 th/uL,),with 89% lymphs (20-40%); CD3 = 90% (60-80%); CD5 = 87% (60-80%); CD10 = 0% (< 1%); CD4 = 88% (30-65%); CD20 = 12% (5-20%); CD34 = 0% (< 1%); CD8 = 3% (10-40%); kappa = 10% (3-15%); lambda = 5% (2-10%); CD19 = 15% (5-20%).

A CBC,differential,and flow cytometry were performed on a patient with the following results (normal values): WBC = 8.0 th/uL (5.0-10.0 th/uL),diff = 90% lymphs (20-40%),CD3 = 5% (60-80%),CD5 = 95% (60-80%),CD19 = 95% (5-20%),CD10 = 0% (0%),surface Ig = pos (positive),and cytoplasmic Ig = neg (negative).What disease does this patient have?

What is the interpretation of the following patient results? (normal values)WBC = 7.0 th/uL (5.0-10.0 th/uL),with 89% blasts; CD3 = 10% (60-80%); CD5 = 9% (60-80%); CD10 = 89% (< 1%); CD4 = 6% (30-65%); CD20 = 0% (5-20%); CD34 = 94% (< 1%); CD8 = 3% (10-40%); kappa = 0% (3-15%); lambda = 0% (2-10%); CD19 = 90% (5-20%).

What is the main difference between leukemias and lymphomas?

Which immunoproliferative disorder is a cancer of the plasma cells and results in secretion of light chains into the urine?

What is the interpretation of the following patient results? (normal values)WBC = 25.0 th/uL (5.0-10.0 th/uL),with 78% blasts; CD3 = 83% (60-80%); CD5 = 90% (60-80%); CD10 = 2% (< 1%); CD4 = 85% (30-65%); CD20 = 1% (5-20%); CD34 = 0% (< 1%); CD8 = 87% (10-40%); kappa = 1% (3-15%); lambda = 0% (2-10%); CD19 = 2% (5-20%).

A 55-year-old male presents with symptoms that include weakness,loss of appetite,and anemia.Immunofixation electrophoresis reveals a heavy IgM band.Which of the following is the most likely diagnosis?

Which best describes the difference between chronic and acute lymphocytic leukemias?