One small region of a human kidney tubule known as the thick ascending limb (or TAL)has tight junctions that are permeable to magnesium (Mg2+)ions.What is thought to account for the permeability of this tight junction to magnesium ions?

A) The membrane in this region is leaky because of special phospholipids. B) Loops of claudin molecules that extend into the extracellular space form pores in the TAL. C) Loops of claudin molecules that extend into the cytoplasm form pores in the TAL. D) Loops of claudin molecules fully embedded in the TAL membrane form pores in the TAL. E) Claudin molecules form gap junctions that allow the passage of magnesium ions. A) The membrane in this region is leaky because of special phospholipids. B) Loops of claudin molecules that extend into the extracellular space form pores in the TAL. C) Loops of claudin molecules that extend into the cytoplasm form pores in the TAL. D) Loops of claudin molecules fully embedded in the TAL membrane form pores in the TAL. E) Claudin molecules form gap junctions that allow the passage of magnesium ions.

Exam 7: Interactions Between Cells and Their Environment

You place mammary gland epithelial cells in culture and then treat them with enzymes that digest the surrounding extracellular matrix.What happens?

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(Multiple Choice)

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Question 1

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The binding of lymphocytes to the endothelial lining of venules in peripheral lymph node frozen tissue sections could be blocked in what way? This demonstrated the existence of what kind of molecule?

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Question 2

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What explains the fact that plants lack the specialized junctions seen in animal cells?

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Question 3

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Verified

Despite the presence of the blood-brain barrier,what cells,oddly enough,can pass through the blood-brain barrier by sending a signal that opens up the junction?

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Question 4

Pemphigus vulgaris __________.

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Question 5

Basement membranes contain Type IV collagen,a nonfibrillar collagen organized in a flattened network.The Type IV collagen trimer has some interspersed nonhelical segments.What property does this confer upon basement membranes?

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Question 6

The loss of cadherin function may be instrumental in what disease state?

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Question 7

The cells of the epiblast of a developing mammalian embryo display what cell adhesion molecules on their surfaces,molecules that presumably promote their close association with one another?

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Question 8

To what is the cytoplasmic domain of integrins in the region of a focal contact connected via various adaptors?

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Question 9

You coat a Petri dish with fibronectin and proteoglycans and culture cells on the dish.The cells adhere to the dish.You repeat the experiment but this time add RGD tripeptides to the culture dish as the cells are added.What happens?

(Multiple Choice)

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Question 10

What is thought to promote the release of future mesoderm cells from an epithelium and their transformation into mesenchymal cells?

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Question 11

You are given a tissue that has a large fibrillar component.The fibers are aligned parallel to each other and the long axis of the tissue.What can you conclude about the pulling forces experienced by this tissue?

(Essay)

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Question 12

Epidermolysis bullosa,an inherited blistering disease,is caused by ________.

(Multiple Choice)

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Question 13

Focal adhesions ________.

(Multiple Choice)

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Question 14

Desmosomes are particularly numerous in tissues _____________.

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Question 15

What would be the effect on primordial germ cells when an embryo is exposed to laminin-specific antibodies?

(Multiple Choice)

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Question 16

L1 is an IgSF molecule that has been shown to be important in neural development; it is thought that it may be involved in axon growth within the embryonic nervous system.What evidence supports this statement?

(Multiple Choice)

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Question 17

Why do cells flatten out as they make contact with a surface?

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Question 18

One small region of a human kidney tubule known as the thick ascending limb (or TAL)has tight junctions that are permeable to magnesium (Mg²⁺)ions.What is thought to account for the permeability of this tight junction to magnesium ions?

(Multiple Choice)

4.9/5

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Question 19

In an integrin,what structure is it that crosses the lipid bilayer?

(Multiple Choice)

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Question 20

Showing 1 - 20 of 97

You place mammary gland epithelial cells in culture and then treat them with enzymes that digest the surrounding extracellular matrix.What happens?

The binding of lymphocytes to the endothelial lining of venules in peripheral lymph node frozen tissue sections could be blocked in what way? This demonstrated the existence of what kind of molecule?

What explains the fact that plants lack the specialized junctions seen in animal cells?

Despite the presence of the blood-brain barrier,what cells,oddly enough,can pass through the blood-brain barrier by sending a signal that opens up the junction?

Pemphigus vulgaris __________.

Basement membranes contain Type IV collagen,a nonfibrillar collagen organized in a flattened network.The Type IV collagen trimer has some interspersed nonhelical segments.What property does this confer upon basement membranes?

The loss of cadherin function may be instrumental in what disease state?

The cells of the epiblast of a developing mammalian embryo display what cell adhesion molecules on their surfaces,molecules that presumably promote their close association with one another?

To what is the cytoplasmic domain of integrins in the region of a focal contact connected via various adaptors?

You coat a Petri dish with fibronectin and proteoglycans and culture cells on the dish.The cells adhere to the dish.You repeat the experiment but this time add RGD tripeptides to the culture dish as the cells are added.What happens?

What is thought to promote the release of future mesoderm cells from an epithelium and their transformation into mesenchymal cells?

You are given a tissue that has a large fibrillar component.The fibers are aligned parallel to each other and the long axis of the tissue.What can you conclude about the pulling forces experienced by this tissue?

Epidermolysis bullosa,an inherited blistering disease,is caused by ________.

Focal adhesions ________.

Desmosomes are particularly numerous in tissues _____________.

What would be the effect on primordial germ cells when an embryo is exposed to laminin-specific antibodies?

L1 is an IgSF molecule that has been shown to be important in neural development; it is thought that it may be involved in axon growth within the embryonic nervous system.What evidence supports this statement?

Why do cells flatten out as they make contact with a surface?

One small region of a human kidney tubule known as the thick ascending limb (or TAL)has tight junctions that are permeable to magnesium (Mg²⁺)ions.What is thought to account for the permeability of this tight junction to magnesium ions?

In an integrin,what structure is it that crosses the lipid bilayer?

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics,enzymes and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Cytoplasmic Membrane Systems: Structure, function, and Membrane Trafficking

The Cytoskeleton and Cell Motility

The Nature of the Gene and the Genome

Gene Expression: From Transcription to Translation

Control of Gene Expression

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

Cancer

The Immune Response

Techniques in Cell and Molecular Biology

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