Question 1

Compared with eukaryotic chromosomes,bacterial chromosomes are ________.

Accepted Answer

A) large,mainly organized in single gene transcription units without introns 
B) small,mainly organized in single gene transcription units with introns 
C) large,mainly organized in polygenic transcription units without introns 
D) small,with high gene density 
E) large,triple-helix,Z-DNA,organized in single gene units with introns 
A) large,mainly organized in single gene transcription units without introns 
B) small,mainly organized in single gene transcription units with introns 
C) large,mainly organized in polygenic transcription units without introns 
D) small,with high gene density 
E) large,triple-helix,Z-DNA,organized in single gene units with introns

Question 2

The terms proteomics and genomics mean essentially the same thing.

Accepted Answer

A) True 
 B)False

Question 3

Present an overview of the gene organization in large-genome plants.

Accepted Answer

Large-genome plants are characterized by

Question 4

How are pseudogenes formed?

Accepted Answer

probably through point mutatio

Question 5

What appears to be the range of the number of protein-coding genes per genome in eukaryotes?

Accepted Answer

5000 to ab

Question 6

Humans have more DNA and more genes than any other organism.

Accepted Answer

A) True 
 B)False

Question 7

In general,the organization of genes in bacteria is different from that in eukaryotes.In E.coli,approximately 27 percent of all genes are organized into contiguous,functionally related units containing multiple genes under coordinate control that are transcribed as a single unit.Such contiguous gene families are called ________.

Accepted Answer

A) transcriptomes 
B) proteomes 
C) contigs 
D) operons 
E) pseudogenes 
A) transcriptomes 
B) proteomes 
C) contigs 
D) operons 
E) pseudogenes

Question 8

Compared with prokaryotic chromosomes,eukaryotic chromosomes are ________.

Accepted Answer

A) large,mainly organized in single gene transcription units without introns 
B) small,mainly organized in single gene transcription units with introns 
C) large,mainly organized in polygenic transcription units without introns 
D) small,mainly organized in polygenic transcription units without introns 
E) large,linear,less densely packed with protein-coding genes,mainly organized in single gene units with introns 
A) large,mainly organized in single gene transcription units without introns 
B) small,mainly organized in single gene transcription units with introns 
C) large,mainly organized in polygenic transcription units without introns 
D) small,mainly organized in polygenic transcription units without introns 
E) large,linear,less densely packed with protein-coding genes,mainly organized in single gene units with introns

Question 9

What is comparative genomics?

Accepted Answer

Comparative genomics is a relatively new

Question 10

What is one major limitation of two-dimensional gel electrophoresis (2DGE)?

Accepted Answer

A) It is extremely costly to execute in a typical molecular biology laboratory. 
B) When products are separated,they tend to leach out of the gel matrix. 
C) Only the most abundant products are detected. 
D) 2DGE can be run only on nucleic acids. 
E) 2DGE is useful only in separating eukaryotic gene products. 
A) It is extremely costly to execute in a typical molecular biology laboratory. 
B) When products are separated,they tend to leach out of the gel matrix. 
C) Only the most abundant products are detected. 
D) 2DGE can be run only on nucleic acids. 
E) 2DGE is useful only in separating eukaryotic gene products.

Question 11

Proteomics is the ________.

Accepted Answer

A) process of defining the complete set of proteins encoded by a genome 
B) harvesting of proteins from a cell to determine their economic value 
C) manipulation of amino acid sequences in proteins to alter their function 
D) changing of the terminal sequences of proteins to alter their function 
E) rational design of drugs based on protein structure 
A) process of defining the complete set of proteins encoded by a genome 
B) harvesting of proteins from a cell to determine their economic value 
C) manipulation of amino acid sequences in proteins to alter their function 
D) changing of the terminal sequences of proteins to alter their function 
E) rational design of drugs based on protein structure

Question 12

Mycoplasma are among the smallest and perhaps the simplest self-replicating prokaryotes known.M.genitalium contains a genome of 0.58 Mb.Approximately how many genes does this bacterium contain?

Accepted Answer

A) 426,000 
B) 3000 
C) 1200 
D) between 400 and 550 
E) 12 
A) 426,000 
B) 3000 
C) 1200 
D) between 400 and 550 
E) 12

Question 13

Present a general definition for a multigene family and how it relates to a superfamily.

Accepted Answer

Multigene families share DNA sequence ho

Question 14

Briefly describe general trends relating to DNA content and gene number in major groups of organisms.

Accepted Answer

Eukaryotes contain more DNA in their gen

Question 15

Describe the organization of the α-globin gene in humans.

Accepted Answer

The α-group spans more than 30 kb and co

Question 16

One major difference between prokaryotic and eukaryotic genes is that eukaryotic genes can contain internal sequences,called ________,that get removed in the mature message.

Accepted Answer

intervenin

Question 17

Describe the relationship between introns (size and number)and organismic complexity in eukaryotes.

Accepted Answer

Going from yeast to multicellu

Question 18

In humans,no genes are larger than 2 kb.

Accepted Answer

A) True 
 B)False

Question 19

In what way will the discipline called metagenomics contribute to human health and welfare?

Accepted Answer

Metagenomics,also called environmental g

Question 20

A number of generalizations can be made about the organization of protein-coding genes in bacterial chromosomes.First,the gene density is very high,averaging about ________.

Accepted Answer

one gene p

Exam 18: Genomics,Bioinformatics,and Proteomics

Compared with eukaryotic chromosomes,bacterial chromosomes are ________.

The terms proteomics and genomics mean essentially the same thing.

Present an overview of the gene organization in large-genome plants.

How are pseudogenes formed?

What appears to be the range of the number of protein-coding genes per genome in eukaryotes?

Humans have more DNA and more genes than any other organism.

Compared with prokaryotic chromosomes,eukaryotic chromosomes are ________.

What is comparative genomics?

What is one major limitation of two-dimensional gel electrophoresis (2DGE)?

Proteomics is the ________.

Mycoplasma are among the smallest and perhaps the simplest self-replicating prokaryotes known.M.genitalium contains a genome of 0.58 Mb.Approximately how many genes does this bacterium contain?

Present a general definition for a multigene family and how it relates to a superfamily.

Briefly describe general trends relating to DNA content and gene number in major groups of organisms.

Describe the organization of the α-globin gene in humans.

One major difference between prokaryotic and eukaryotic genes is that eukaryotic genes can contain internal sequences,called ________,that get removed in the mature message.

Describe the relationship between introns (size and number)and organismic complexity in eukaryotes.

In humans,no genes are larger than 2 kb.

In what way will the discipline called metagenomics contribute to human health and welfare?

A number of generalizations can be made about the organization of protein-coding genes in bacterial chromosomes.First,the gene density is very high,averaging about ________.

Introduction to Genetics

Mitosis and Meiosis

Mendelian Genetics

Modification of Mendelian Ratios

Sex Determination and Sex Chromosomes

Chromosome Mutations: Variation in Number and Arrangement

Linkage and Chromosome Mapping in Eukaryotes

Genetic Analysis and Mapping in Bacteria and Bacteriophages

DNA structure and Analysis

DNA Replication and Recombination

Chromosome Structure and DNA Sequence Organization

The Genetic Code and Transcription

Translation and Proteins

Gene Mutation,DNA Repair,and Transposition

Regulation of Gene Expression

The Genetics of Cancer

Recombinant DNA Technology

Applications and Ethics of Genetic Engineering and Biotechnology

Developmental Genetics

Quantitative Genetics and Multifactorial Traits

Population and Evolutionary Genetics

Conservation Genetics

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