Exam 5: Growth Factors,receptors,and Cancer

In cells infected with simian sarcoma virus,the sis oncogene causes the cells to release increased amounts of Sis protein,which is recognized by PDGF-receptor molecules on the cells' surface.This type of signaling loop is an example of

Mutations in the EGF receptor EGF-R)that contribute to the development of cancer are MOST often due to

Cell surface receptors that are able to create mechanical stability by tethering cells to the extracellular matrix ECM)are known as

Which of the following statements is TRUE of the ligands of nuclear receptors?

Which of the following statements is FALSE regarding Ras mutations in cancer patients?

When a growth factor receptor is not bound to ligand,it is MOST likely in what configuration?

Ligand-independent signaling of receptor-tyrosine kinases can result from

Which of the following statements about TGF-β receptors is FALSE?

Overexpression of growth receptors helps to promote cancer growth by

Which of the following is NOT an example of a tyrosine kinase growth factor receptor that is often altered in cancer cells?

Which of the following is NOT true of the Src protein?

You are growing NIH 3T3 mouse embryonic fibroblasts)in a Petri dish.You provide these cells with a medium containing amino acids,glucose,vitamins,and salts necessary for their survival,but you run out of serum to supplement the medium.Without the addition of serum,what will MOST likely happen to these cells?