Question 1

Which of the following is NOT a type of post-translational modification?

Accepted Answer

A) A change in the base sequences of DNA 
B) Cleavage of a protein product by proteases 
C) Addition of lipid groups to the protein chain 
D) Glycosylation 
E) Methylation 
A) A change in the base sequences of DNA 
B) Cleavage of a protein product by proteases 
C) Addition of lipid groups to the protein chain 
D) Glycosylation 
E) Methylation A

Question 2

cancer cells exhibit aneuploidy,meaning that they

Accepted Answer

A) Proliferate at higher rates than normal cells. 
B) Exhibit higher rates of apoptosis than normal cells. 
C) Have an abnormal number of chromosomes. 
D) Have a normal number of autosomes. 
E) Have mutations in genes involved in the cell cycle. 
A) Proliferate at higher rates than normal cells. 
B) Exhibit higher rates of apoptosis than normal cells. 
C) Have an abnormal number of chromosomes. 
D) Have a normal number of autosomes. 
E) Have mutations in genes involved in the cell cycle. C

Question 3

a hypothetical cross between two fruit flies,one with red eyes and one with white eyes,all resulting progeny had red eyes.This would suggest that

Accepted Answer

A) The red-eyed trait is recessive to white eyes. 
B) The red-eyed trait is dominant to white eyes. 
C) The red-eyed and white-eyed genes are co-dominant. 
D) The eye color trait is most likely coded for by multiple genes. 
E) None of the above. 
A) The red-eyed trait is recessive to white eyes. 
B) The red-eyed trait is dominant to white eyes. 
C) The red-eyed and white-eyed genes are co-dominant. 
D) The eye color trait is most likely coded for by multiple genes. 
E) None of the above. B

Question 4

Which of the following can contribute to the initiation of cancer?

Accepted Answer

A) Somatic mutations 
B) Germ-line mutations 
C) Gene amplification 
D) Aneuploidy 
E) All of the above 
A) Somatic mutations 
B) Germ-line mutations 
C) Gene amplification 
D) Aneuploidy 
E) All of the above

Question 5

Which of the following is true of orthologous genes?

Accepted Answer

A) They are genes in different species that evolved from a common ancestor. 
B) They code for proteins having different functions. 
C) They are genes located on the same chromosome. 
D) They are related genes within the same species. 
E) All of the above. 
A) They are genes in different species that evolved from a common ancestor. 
B) They code for proteins having different functions. 
C) They are genes located on the same chromosome. 
D) They are related genes within the same species. 
E) All of the above.

Question 6

expression of a given gene may be influenced by

Accepted Answer

A) Activating transcription factors 
B) Enhancer sequences 
C) Histone modifications 
D) Changes in chromatin structure 
E) All of the above 
A) Activating transcription factors 
B) Enhancer sequences 
C) Histone modifications 
D) Changes in chromatin structure 
E) All of the above

Question 7

The discovery of which of the following enzymes allowed researchers to synthesize complementary DNA from mRNA in vitro?

Accepted Answer

A) DNA ligase 
B) DNA polymerase 
C) DNA synthetase 
D) Reverse transcriptase 
E) None of the above 
A) DNA ligase 
B) DNA polymerase 
C) DNA synthetase 
D) Reverse transcriptase 
E) None of the above

Question 8

Which of the following is NOT true of somatic mutations?

Accepted Answer

A) They occur in non-germ-line cells. 
B) They can be passed on to lineal descendants of the cell that was mutated. 
C) They may occur at any time during an individual's lifetime. 
D) They can be passed on from parent to child. 
E) They often play a role in cancer formation. 
A) They occur in non-germ-line cells. 
B) They can be passed on to lineal descendants of the cell that was mutated. 
C) They may occur at any time during an individual's lifetime. 
D) They can be passed on from parent to child. 
E) They often play a role in cancer formation.

Question 9

Which of the following would be LEAST likely to contribute to transformation of a cell?

Accepted Answer

A) A mutation resulting in a change in splicing 
B) A mutation in a transcription factor 
C) A silent mutation in an intron 
D) An activating mutation in an exon of a gene coding for a protein that promotes cellular proliferation 
E) Changes in the expression level of a miRNA that is involved in protein synthesis 
A) A mutation resulting in a change in splicing 
B) A mutation in a transcription factor 
C) A silent mutation in an intron 
D) An activating mutation in an exon of a gene coding for a protein that promotes cellular proliferation 
E) Changes in the expression level of a miRNA that is involved in protein synthesis

Question 10

Which of the following types of changes would most likely NOT be associated with increased cancer risk?

Accepted Answer

A) A mutation resulting in higher levels of K-Ras expression 
B) Reduced expression of HOTAIR lncRNA 
C) Loss of function of the Dicer enzyme 
D) A mutation in K-Ras that prevents recognition by Let-7 
E) None of the above 
A) A mutation resulting in higher levels of K-Ras expression 
B) Reduced expression of HOTAIR lncRNA 
C) Loss of function of the Dicer enzyme 
D) A mutation in K-Ras that prevents recognition by Let-7 
E) None of the above

Question 11

template on which ribosomes assemble the amino acids that form proteins is known as

Accepted Answer

A) hnRNA 
B) messenger RNA 
C) ribosomal RNA 
D) DNA 
E) None of the above 
A) hnRNA 
B) messenger RNA 
C) ribosomal RNA 
D) DNA 
E) None of the above

Question 12

Which of the following mutations would be MOST likely to be retained in a species gene pool?

Accepted Answer

A) A mutation resulting in a deleterious change in a cytoskeletal protein structure 
B) A mutation in an exon of a gene coding for DNA repair 
C) A mutation in an intron of a gene coding for DNA repair 
D) Both A and B 
E) None of the above 
A) A mutation resulting in a deleterious change in a cytoskeletal protein structure 
B) A mutation in an exon of a gene coding for DNA repair 
C) A mutation in an intron of a gene coding for DNA repair 
D) Both A and B 
E) None of the above

Which of the following is NOT a type of post-translational modification?

cancer cells exhibit aneuploidy,meaning that they

a hypothetical cross between two fruit flies,one with red eyes and one with white eyes,all resulting progeny had red eyes.This would suggest that

Which of the following can contribute to the initiation of cancer?

Which of the following is true of orthologous genes?

expression of a given gene may be influenced by

The discovery of which of the following enzymes allowed researchers to synthesize complementary DNA from mRNA in vitro?

Which of the following is NOT true of somatic mutations?

Which of the following would be LEAST likely to contribute to transformation of a cell?

Which of the following types of changes would most likely NOT be associated with increased cancer risk?

template on which ribosomes assemble the amino acids that form proteins is known as

Which of the following mutations would be MOST likely to be retained in a species gene pool?

The Nature of Cancer

Tumor Viruses

Cellular Oncogenes

Growth Factors,receptors,and Cancer

Cytoplasmic Signaling Circuitry Programs Many of the Traits of Cancer

Tumor Suppressor Genes

Prb and Control of the Cell Cycle Clock

P53 and Apoptosis: Master Guardian and Executioner

Eternal Life: Cell Immortalization and Tumorigenesis

Multi-Step Tumorigenesis

Maintenance of Genomic Integrity and the Development of Cancer

Dialogue Replaces Monologue: Heterotypic Interactions and the Biology of Angiogenesis

Moving Out: Invasion and Metastasis

Crowd Control: Tumor Immunology and Immunotherapy

The Rational Treatment of Cancer

Filters

Exam 1: The Biology and Genetics of Cells and Organisms

Which of the following is NOT a type of post-translational modification?

cancer cells exhibit aneuploidy,meaning that they

a hypothetical cross between two fruit flies,one with red eyes and one with white eyes,all resulting progeny had red eyes.This would suggest that

Which of the following can contribute to the initiation of cancer?

Which of the following is true of orthologous genes?

expression of a given gene may be influenced by

The discovery of which of the following enzymes allowed researchers to synthesize complementary DNA from mRNA in vitro?

Which of the following is NOT true of somatic mutations?

Which of the following would be LEAST likely to contribute to transformation of a cell?

Which of the following types of changes would most likely NOT be associated with increased cancer risk?

template on which ribosomes assemble the amino acids that form proteins is known as

Which of the following mutations would be MOST likely to be retained in a species gene pool?

The Nature of Cancer

Tumor Viruses

Cellular Oncogenes

Growth Factors,receptors,and Cancer

Cytoplasmic Signaling Circuitry Programs Many of the Traits of Cancer

Tumor Suppressor Genes

Prb and Control of the Cell Cycle Clock

P53 and Apoptosis: Master Guardian and Executioner

Eternal Life: Cell Immortalization and Tumorigenesis

Multi-Step Tumorigenesis

Maintenance of Genomic Integrity and the Development of Cancer

Dialogue Replaces Monologue: Heterotypic Interactions and the Biology of Angiogenesis

Moving Out: Invasion and Metastasis

Crowd Control: Tumor Immunology and Immunotherapy

The Rational Treatment of Cancer

Filters