Exam 5: Dna Structure, Replication, and Recombination

The Holliday model of recombination has been modified.The current model,termed the consensus model,is now consistent with current research.What are the five properties of recombination,as they are now understood?

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Question 1

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1.Homologs physically break,exchange parts,and rejoin.
2.Breakage and repair create reciprocal products of recombination.
3.Recombination events can occur anywhere along the DNA molecule.
4.The exchange is precise,there is no gain or loss of nucleotides.
5.Gene conversion can give rise to an unequal yield of two different alleles.

Describe the process of nucleosome decompaction that allows the transcription of RNA.

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Some loosening of individual nucleosomes must occur at the beginning of genes.Some of the nonhistone proteins known as transcription factors carry out this task by unwinding nucleosomes and dislodging histones from DNA at the 5' end of genes where transcription will begin.The nucleosome-free regions are now decompacted enough for RNA polymerase and other transcription factors to have access to the DNA and thus allow recognition of promoter regions and initiate gene expression.

You examine cells with a microscope and detect that there are two Barr bodies present in each cell.What is the most likely genotype of the cells?

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An electron micrograph of chromatin,which looks like a bead on a string,allows measurement of structural dimensions.The beads appear to have a diameter of about Å and the string has a diameter of about Å.

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Question 4

The 10,000 origins of replication in mammalian cells suggests that concerning origin of replication there is

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Question 5

The enzyme that some organisms use to replicate DNA at the 5' ends of chromosomes is called

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Question 6

Nucleosomes are evenly spaced along a chromosome,but they do not have a well-defined arrangement within the chromatin.

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Question 7

By weight,chromatin consists roughly of

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Question 8

Recombination occurs during meiotic ________.

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Question 9

Which of the following is not true about DNA polymerase?

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Question 10

Histones are small proteins composed of a preponderance of basic negatively charged amino acids.

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Question 11

One of the functions of a centromere is to contribute to proper chromosome segregation.The other function is to

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Question 12

Cohesins are a multisubunit protein complex that glue sister chromatids together after chromosome replication in the S phase of the cell cycle.

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Question 13

The total compaction of DNA as seen in metaphase chromosomes is approximately ______ fold.

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Question 14

In DNA,the 300Å fibre is formed into structural loops.Responsibility for this function appears to lie with

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Question 15

Histones and DNA have a strong attraction for each other because

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Question 16

At what stage of mitosis do we first see a chromosome that is compacted 250-fold over the 40-fold compacted 300Å fibre?

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Question 17

Recombination involves the breakage and reunion of DNA molecules from

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Question 18

In which of the following cases will a Barr body be seen?

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Question 19

Which is of the following statements about the double strand break-repair model is true?

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Question 20

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Exam 5: Dna Structure, Replication, and Recombination

The Holliday model of recombination has been modified.The current model,termed the consensus model,is now consistent with current research.What are the five properties of recombination,as they are now understood?

Describe the process of nucleosome decompaction that allows the transcription of RNA.

You examine cells with a microscope and detect that there are two Barr bodies present in each cell.What is the most likely genotype of the cells?

An electron micrograph of chromatin,which looks like a bead on a string,allows measurement of structural dimensions.The beads appear to have a diameter of about ________ Å and the string has a diameter of about ________ Å.

The 10,000 origins of replication in mammalian cells suggests that concerning origin of replication there is

The enzyme that some organisms use to replicate DNA at the 5' ends of chromosomes is called

Nucleosomes are evenly spaced along a chromosome,but they do not have a well-defined arrangement within the chromatin.

By weight,chromatin consists roughly of

Recombination occurs during meiotic ________.

Which of the following is not true about DNA polymerase?

Histones are small proteins composed of a preponderance of basic negatively charged amino acids.

One of the functions of a centromere is to contribute to proper chromosome segregation.The other function is to

Cohesins are a multisubunit protein complex that glue sister chromatids together after chromosome replication in the S phase of the cell cycle.

The total compaction of DNA as seen in metaphase chromosomes is approximately ______ fold.

In DNA,the 300Å fibre is formed into structural loops.Responsibility for this function appears to lie with

Histones and DNA have a strong attraction for each other because

At what stage of mitosis do we first see a chromosome that is compacted 250-fold over the 40-fold compacted 300Å fibre?

Recombination involves the breakage and reunion of DNA molecules from

In which of the following cases will a Barr body be seen?

Which is of the following statements about the double strand break-repair model is true?

Mendels Principles of Heredity

Extensions to Mendels Laws

The Chromosome Theory of Inheritance

Linkage, Recombination, and the Mapping of Genes on Chromosomes

Anatomy and Function of a Gene: Dissection Through Mutation

Gene Expression: the Flow of Information From Dna to Rna to Protein

Digital Analysis of Genomes

Genome Annotation

Analyzing Genomic Variation

The Eukaryotic Chromosome

Chromosomal Rearrangements and Changes in Chromosome Number

Bacterial Genetics

Organellar Inheritance

Gene Regulation in Prokaryotes

Gene Regulation in Eukaryotes

Manipulating the Genomes of Eukaryotes

The Genetic Analysis of Development

The Genetics of Cancer

Variation and Selection in Populations

Genetics of Complex Traits

Exploring Synthetic Biology: Concepts, Techniques, and Applications

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An electron micrograph of chromatin,which looks like a bead on a string,allows measurement of structural dimensions.The beads appear to have a diameter of about Å and the string has a diameter of about Å.