Question 1

Bicoid is a maternal-effect mutation that results in larvae with two heads.

Accepted Answer

A) True 
 B)False  False

Question 2

Signaling factors that complete cell-to-cell communication in the form of direct contact are called

Accepted Answer

A)  juxtacrine factors. 
B)  paracrine factors. 
C)  endocrine factors. 
D)  exocrine factors. 
E)  autocrine factors. 
A)  juxtacrine factors. 
B)  paracrine factors. 
C)  endocrine factors. 
D)  exocrine factors. 
E)  autocrine factors. A

Question 3

What three characteristics of value to geneticists do model organisms share?

Accepted Answer

Ease of cultivation,rapid reproduction,and small size.

Question 4

Bicoid is a maternal protein deposited in the anterior region of the egg in Drosophila.

Accepted Answer

A) True 
 B)False

Question 5

How do cells which all contain identical genetic information differentiate into myriad cell types and ultimately undergo the "miracle" of development from an embryo into a child?

Accepted Answer

Gene regulation controls the t

Question 6

Which of the following is a zygotic gap gene in Drosophila?

Accepted Answer

A)  knirps (kni) 
B)  even-skipped (eve) 
C)  caudal (cad) 
D)  hedgehog (hh) 
E)  agamous (ag) 
A)  knirps (kni) 
B)  even-skipped (eve) 
C)  caudal (cad) 
D)  hedgehog (hh) 
E)  agamous (ag)

Question 7

One action of the Bicoid protein is to repress the translation of the caudal (cdl)transcripts.

Accepted Answer

A) True 
 B)False

Question 8

What is the molecular basis of haploinsufficiency?

Accepted Answer

The molecular basis of haploin

Question 9

You recover Drosophila embryos in which,instead of having a head region and tail region,have two tail regions in mirror-image arrangement.Describe a maternal mutation that could cause this condition.

Accepted Answer

If the female parent is homozygous for a

Question 10

An example of ectopic gene expression is shown by

Accepted Answer

A)  achondroplastic dwarfism. 
B)  lack of eye development. 
C)  abnormal vulvar shape. 
D)  legs instead of antennae. 
E)  stem cells. 
A)  achondroplastic dwarfism. 
B)  lack of eye development. 
C)  abnormal vulvar shape. 
D)  legs instead of antennae. 
E)  stem cells.

Question 11

A cloned organism will always be genotypically and phenotypically identical to the individual from which it was cloned.

Accepted Answer

A) True 
 B)False

Question 12

The presence of a homeodomain in a protein suggests what about its function?

Accepted Answer

A)  It has kinase activity. 
B)  It is a membrane bound receptor. 
C)  It is a secreted protein. 
D)  It is a transcription factor. 
E)  It has phosphorylase activity. 
A)  It has kinase activity. 
B)  It is a membrane bound receptor. 
C)  It is a secreted protein. 
D)  It is a transcription factor. 
E)  It has phosphorylase activity.

Question 13

Due to ethical considerations,development is studied in model organisms.How do you use genetic information gained from other species to isolate the human genes involved in development?

Accepted Answer

You can use genes cloned in ot

Question 14

A nurse cell produces large amounts of mRNA and proteins for deposit into the Drosophila egg.

Accepted Answer

A) True 
 B)False

Question 15

Maternal mRNA transcripts of the bicoid (bcd)gene are deposited in the anterior portion of the egg in Drosophila.

Accepted Answer

A) True 
 B)False

Question 16

What technique would you use to best determine when and in what cells of a given tissue a specific gene is expressed?

Accepted Answer

A)  Northern analysis 
B)  In situ hybridization 
C)  RT-PCR 
D)  Southern analysis 
E)  PCR 
A)  Northern analysis 
B)  In situ hybridization 
C)  RT-PCR 
D)  Southern analysis 
E)  PCR

Question 17

In Drosophila,two maternal transcripts that are distributed evenly throughout the oocyte prior to fertilization are:

Accepted Answer

A)  caudal and knirps 
B)  bicoid and nanos 
C)  caudal and hunchback 
D)  agamous and hunchback 
E)  caudal and agamous 
A)  caudal and knirps 
B)  bicoid and nanos 
C)  caudal and hunchback 
D)  agamous and hunchback 
E)  caudal and agamous

Question 18

What advantages,in particular,do yeast cells provide with respect to the study of eukaryotes?

Accepted Answer

Yeast cells are single celled

Question 19

Mutations that disrupt the earliest stages of human development almost always cause

Accepted Answer

A)  no effect. 
B)  polydactyly. 
C)  spontaneous abortion. 
D)  disruption of the segmented body plan. 
E)  immunodeficiency. 
A)  no effect. 
B)  polydactyly. 
C)  spontaneous abortion. 
D)  disruption of the segmented body plan. 
E)  immunodeficiency.

Question 20

A ligand secreted from a cell to a nearby cell that signals developmental differentiation is called

Accepted Answer

A)  juxtacrine factor. 
B)  paracrine factor. 
C)  endocrine factor. 
D)  exocrine factor. 
E)  autonomous factor. 
A)  juxtacrine factor. 
B)  paracrine factor. 
C)  endocrine factor. 
D)  exocrine factor. 
E)  autonomous factor.

Exam 16: Gene Regulation in Eukaryotes

Bicoid is a maternal-effect mutation that results in larvae with two heads.

Signaling factors that complete cell-to-cell communication in the form of direct contact are called

What three characteristics of value to geneticists do model organisms share?

Bicoid is a maternal protein deposited in the anterior region of the egg in Drosophila.

How do cells which all contain identical genetic information differentiate into myriad cell types and ultimately undergo the "miracle" of development from an embryo into a child?

Which of the following is a zygotic gap gene in Drosophila?

One action of the Bicoid protein is to repress the translation of the caudal (cdl)transcripts.

What is the molecular basis of haploinsufficiency?

You recover Drosophila embryos in which,instead of having a head region and tail region,have two tail regions in mirror-image arrangement.Describe a maternal mutation that could cause this condition.

An example of ectopic gene expression is shown by

A cloned organism will always be genotypically and phenotypically identical to the individual from which it was cloned.

The presence of a homeodomain in a protein suggests what about its function?

Due to ethical considerations,development is studied in model organisms.How do you use genetic information gained from other species to isolate the human genes involved in development?

A nurse cell produces large amounts of mRNA and proteins for deposit into the Drosophila egg.

Maternal mRNA transcripts of the bicoid (bcd)gene are deposited in the anterior portion of the egg in Drosophila.

What technique would you use to best determine when and in what cells of a given tissue a specific gene is expressed?

In Drosophila,two maternal transcripts that are distributed evenly throughout the oocyte prior to fertilization are:

What advantages,in particular,do yeast cells provide with respect to the study of eukaryotes?

Mutations that disrupt the earliest stages of human development almost always cause

A ligand secreted from a cell to a nearby cell that signals developmental differentiation is called

Mendels Principles of Heredity

Extensions to Mendels Laws

The Chromosome Theory of Inheritance

Linkage, Recombination, and the Mapping of Genes on Chromosomes

Dna Structure, Replication, and Recombination

Anatomy and Function of a Gene: Dissection Through Mutation

Gene Expression: the Flow of Information From Dna to Rna to Protein

Digital Analysis of Genomes

Genome Annotation

Analyzing Genomic Variation

The Eukaryotic Chromosome

Chromosomal Rearrangements and Changes in Chromosome Number

Bacterial Genetics

Organellar Inheritance

Gene Regulation in Prokaryotes

Manipulating the Genomes of Eukaryotes

The Genetic Analysis of Development

The Genetics of Cancer

Variation and Selection in Populations

Genetics of Complex Traits

Exploring Synthetic Biology: Concepts, Techniques, and Applications

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