Question 1

Areas of the chromosome that remain highly condensed are called .

Accepted Answer

A)  Euchromatin 
B)  Facultative heterochromatin 
C)  Constituative heterochromatin 
D)  Barr body 
A)  Euchromatin 
B)  Facultative heterochromatin 
C)  Constituative heterochromatin 
D)  Barr body B

Question 2

How many types of histone proteins are there?

Accepted Answer

A)  4 
B)  5 
C)  7 
D)  8 
A)  4 
B)  5 
C)  7 
D)  8 B

Question 3

About how many bases of DNA wrap around a histone complex?

Accepted Answer

A)  1,000 
A)  1,000 B

Question 4

Which of the following promote the formation of heterochromatin during metaphase?

Accepted Answer

A)  Radial loop domains 
B)  Condensing and cohesion 
C)  30 nm fibers 
D)  Nucleosomes 
A)  Radial loop domains 
B)  Condensing and cohesion 
C)  30 nm fibers 
D)  Nucleosomes

Question 5

Loop domains are responsible for what level of condensation of the bacterial chromosome?

Accepted Answer

A)  10 fold 
B)  100 fold 
C)  1000 fold 
D)  10,000 fold 
A)  10 fold 
B)  100 fold 
C)  1000 fold 
D)  10,000 fold

Question 6

What term is used to describe highly repetitive DNA?

Accepted Answer

A)  Heterochromatin 
B)  Homochromatin 
C)  Euchromatin 
D)  Prochromatin 
A)  Heterochromatin 
B)  Homochromatin 
C)  Euchromatin 
D)  Prochromatin

Question 7

What is a mechanism of condensation shared by both prokaryotes and eukaryotes?

Accepted Answer

A)  Nucleosomes 
B)  Loop domains 
C)  30 nm fiber 
D)  None of the answers are correct 
A)  Nucleosomes 
B)  Loop domains 
C)  30 nm fiber 
D)  None of the answers are correct

Question 8

Which of the following represents the lowest level of chromosome condensation?

Accepted Answer

A)  Radial loop domain 
B)  30 nm fibers 
C)  Double helix 
D)  Nucleosome 
A)  Radial loop domain 
B)  30 nm fibers 
C)  Double helix 
D)  Nucleosome

Question 9

The origins of replication in eukaryotic chromosomes are spaced about every base pairs.

Accepted Answer

A)  100,000 
B)  1000 
C)  100 
D)  10 
E)  500 
A)  100,000 
B)  1000 
C)  100 
D)  10 
E)  500

Question 10

Viruses are small infectious particles that require a host cell to replicate.

Accepted Answer

A) True 
 B)False

Question 11

Bacteria are small infectious particles that require a host cell to replicate.

Accepted Answer

A) True 
 B)False

Question 12

Over winding of the DNA decreases the number of turns in the double helix, and thus results in super
coils in the DNA.

Accepted Answer

A) True 
 B)False

Question 13

Where is the bacterial chromosome located?

Accepted Answer

A)  Nucleus 
B)  Nucleolus 
C)  Nucleoid 
D)  Nuclear envelope 
A)  Nucleus 
B)  Nucleolus 
C)  Nucleoid 
D)  Nuclear envelope

Question 14

A nucleus is 4 μm in diameter. Its DNA is composed of a million base pairs. Approximately how much does it need to be condensed in order to fit inside the nucleus?

Accepted Answer

A)  30-fold 
B)  100,000-fold 
C)  1 million-fold 
D)  3 million-fold 
A)  30-fold 
B)  100,000-fold 
C)  1 million-fold 
D)  3 million-fold

Question 15

One would expect heterochromatic regions of DNA to be more compacted than euchromatic regions.

Accepted Answer

A) True 
 B)False

Question 16

Where do kinetichores attach to chromosomes?

Accepted Answer

A)  Telomeres 
B)  Specific genes on the chromosome 
C)  Centromeres 
D)  They don't attach to DNA 
A)  Telomeres 
B)  Specific genes on the chromosome 
C)  Centromeres 
D)  They don't attach to DNA

Question 17

Which of the following would introduce more twists into the DNA molecule of a bacterial cell?

Accepted Answer

A)  Negative super coiling 
B)  Positive super coiling 
C)  Chromatin remodeling 
D)  All of the answers are correct 
A)  Negative super coiling 
B)  Positive super coiling 
C)  Chromatin remodeling 
D)  All of the answers are correct

Question 18

An Alu sequence is an example of what?

Accepted Answer

A)  Retro element 
B)  Transposable element 
C)  Highly repetitive DNA 
D)  All of the answers are correct 
A)  Retro element 
B)  Transposable element 
C)  Highly repetitive DNA 
D)  All of the answers are correct

Question 19

Directed assembly viruses means that the subunits of the virus spontaneously bind together to produce
a new virus.

Accepted Answer

A) True 
 B)False

Question 20

What is the purpose of MARs and SARs?

Accepted Answer

A)  To bind to the nuclear matrix 
B)  To form loop structure 
C)  To condense DNA 
D)  All of the answers are correct 
A)  To bind to the nuclear matrix 
B)  To form loop structure 
C)  To condense DNA 
D)  All of the answers are correct

Exam 10: Chromosome Organization and Molecular Structure

Areas of the chromosome that remain highly condensed are called .

How many types of histone proteins are there?

About how many bases of DNA wrap around a histone complex?

Which of the following promote the formation of heterochromatin during metaphase?

Loop domains are responsible for what level of condensation of the bacterial chromosome?

What term is used to describe highly repetitive DNA?

What is a mechanism of condensation shared by both prokaryotes and eukaryotes?

Which of the following represents the lowest level of chromosome condensation?

The origins of replication in eukaryotic chromosomes are spaced about every base pairs.

Viruses are small infectious particles that require a host cell to replicate.

Bacteria are small infectious particles that require a host cell to replicate.

Over winding of the DNA decreases the number of turns in the double helix, and thus results in super coils in the DNA.

Where is the bacterial chromosome located?

A nucleus is 4 μm in diameter. Its DNA is composed of a million base pairs. Approximately how much does it need to be condensed in order to fit inside the nucleus?

One would expect heterochromatic regions of DNA to be more compacted than euchromatic regions.

Where do kinetichores attach to chromosomes?

Which of the following would introduce more twists into the DNA molecule of a bacterial cell?

An Alu sequence is an example of what?

Directed assembly viruses means that the subunits of the virus spontaneously bind together to produce a new virus.

What is the purpose of MARs and SARs?

Overview of Genetics

Mendelian Inheritance

Reproduction and Chromosome Transmission

Extensions of Mendelian Inheritance

Non-Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria and

Variation in Chromosome Structure and Number

Molecular Structure of Dna and Rna

Dna Replication

Gene Transcription and Rna Modification

Translation of Mrna

Gene Regulation in Bacteria and Bacteriophages

Gene Regulation in Eukaryotes

Gene Mutation and Dna Repair

Recombination and Transposition at the Molecular

Recombinant Dna Technology

Biotechnology

Genomics I: Analysis of Dna

Genomics II: Functional Genomics, Proteomics, and

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Quantitative Genetics

Evolutionary Genetics

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