Exam 3: Transmission of Genes From Generation to Generation
In crosses involving complete dominance, the F₂ genotypic ratio is 1:2:1 and is expressed as a phenotypic ratio of ____________________.
3/4 dominant and 1/4 recessive or 3:1 ratio
In Mendel's crosses, pure-breeding individuals were always in the ____________________ generation.
P₁
Does the segregation or separation of members of a gene pair take place at one or both meiotic divisions? If not, which one? What evidence is there to support your answer?
The segregation or separation of members of a gene pair, also known as alleles, occurs during the first meiotic division, which is called meiosis I. Meiosis is a type of cell division that reduces the chromosome number by half, resulting in four daughter cells, each with half the number of chromosomes of the original cell. It consists of two successive divisions: meiosis I and meiosis II.
During meiosis I, homologous chromosomes pair up and exchange genetic material through a process called crossing over. This is followed by the alignment of these pairs at the metaphase plate and their subsequent separation during anaphase I. It is at this stage that the alleles for each gene are segregated into different cells. Each daughter cell receives one chromosome from each homologous pair, thus separating the alleles that were originally together in the diploid parent cell.
Meiosis II resembles a normal mitotic division, where the sister chromatids of each chromosome are separated and distributed to different daughter cells. However, since the alleles were already segregated during meiosis I, meiosis II does not involve the separation of gene pairs.
The evidence for this segregation comes from the observation of genetic inheritance patterns, as first described by Gregor Mendel in the 19th century. Mendel's law of segregation states that the two alleles for each trait separate during gamete formation, and each gamete receives only one allele. This law is a direct consequence of the segregation of homologous chromosomes during meiosis I.
Further evidence for the timing of allele segregation comes from cytogenetic observations under the microscope, where the behavior of chromosomes during meiosis can be directly visualized, and from modern genetic analysis techniques, such as gene mapping and sequencing, which confirm that the alleles are separated into different gametes during meiosis I.
In all Mendel's crosses, it did not matter which phenotype was used as the male or as the female parent.
In his monohybrid crosses, Mendel deduced that one trait was recessive because _____.
In a cross between a true-breeding plant bearing smooth, yellow seeds and a true-breeding plant with wrinkled, green seeds, the offspring were all smooth and yellow. What is the genotype of the F₁ plants?
If a dihybrid cross is begun with a P₁ generation of a plant that produces smooth and yellow peas, crossed with a plant that produces wrinkled green peas, the F₂ plants will have either smooth yellow peas or wrinkled green peas.
Two heterozygous smooth-pea pea plants are crossed (Ss X Ss) and four peas from the cross are randomly selected for examination. The first three are smooth. Must the fourth one be wrinkled? Why or why not?
A cross between two individuals who differ with respect to two gene pairs is a ____________________ cross.
In a pedigree, a double line connecting a married couple indicates that the man and woman are ____________________.
In heterozygous crosses, the phenotypic and genotypic ratios differ for completely dominant traits but are the same for traits showing incomplete dominance.
In the ABO multiple allele system, there are the following combinations of genotypes and phenotypes:
Heterozygotes and dominant homozygotes always have the same phenotype.
In a trait with multiple alleles, an individual carries ____________________ (how many?) alleles of the gene.
Mendel's principle of segregation is directly related to an event that occurs in ______ of meiosis.
In a monohybrid cross with complete dominance, the F₂ offspring should contain _____.
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