Chat with AIExam 12: Genes and Cancer
The BRCA1 and BRCA2 genes both function in the process of ____________________.
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VerifiedDNA repair
How might genetically-engineered human gene products be used to inhibit the action of oncogenes? What type of gene products would you try to develop as anti-oncogene compounds?
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Answered by Examlex AI CopilotGenetically-engineered human gene products could be used to inhibit the action of oncogenes by targeting specific pathways or proteins involved in cancer development. One approach could be to develop gene products that interfere with the signaling pathways activated by oncogenes, thereby preventing the uncontrolled growth and division of cancer cells.
For example, one type of gene product that could be developed as an anti-oncogene compound is a protein that blocks the activity of a specific oncogene or its downstream effectors. This could be achieved by designing a protein that binds to the oncogene or its target proteins, preventing them from carrying out their cancer-promoting functions.
Another approach could be to develop gene products that enhance the activity of tumor suppressor genes, which are natural inhibitors of oncogenes. By increasing the expression or function of tumor suppressor genes, it may be possible to counteract the effects of oncogenes and inhibit cancer growth.
In addition, gene products could be engineered to target the microenvironment of cancer cells, such as the blood vessels that supply them with nutrients and oxygen. By disrupting the support network of cancer cells, it may be possible to inhibit their growth and spread.
Overall, the development of genetically-engineered human gene products as anti-oncogene compounds holds great promise for the future of cancer treatment, offering targeted and potentially more effective therapies for this devastating disease.
Mutation of the APC gene has been identified as the first step toward development of
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The percentage of cancers associated with an inherited predisposition is approximately _________.
(34) Formation of ____________________ is an intermediate stage in the development of colon cancer.
(31) A cellular molecular pathway by which an external signal is converted into a functional response is called ________________.
(23) Chronic myelogenous leukemia is an example of a cancer caused by __________________.
(39) In what part of the cell cycle is expression of BRCA1 and BRCA2 genes highest?
(35) Epigenetic changes that can lead to cancer development involve changes in patterns of _____________.
(29) An autosomal dominant type of colon cancer associated with microsatellite DNA instability is ________________.
(39) The discovery of the nature of the Philadelphia chromosome in myelogenous leukemia represents
(29) The older a person is, the more likely he or she will develop cancer.
(27) Retinoblastoma occurs only in one eye in patients at a low risk of developing other cancers when the ____________________ form is present.
(33) The more cells divide, the more chances for a cancer to develop. Which of the following cells is most likely to give rise to a cancer?
(38) Which of the following is NOT a risk factor associated with cancer?
(35) Targeted drug therapies that stop the growth of cancer cells do so by blocking the action of __________ proteins.
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