Question 1

A chromosome whose centromere is near one end is termed ____________________.

Accepted Answer

acrocentric

Question 2

The region that divides a chromosome into two arms is the ______.

Accepted Answer

A)  centriole 
B)  centromere 
C)  chromatin 
D)  chromatid 
E)  centrum 
A)  centriole 
B)  centromere 
C)  chromatin 
D)  chromatid 
E)  centrum B

Question 3

Fragile sites are chromosome locations that

Accepted Answer

A)  show an increased number of chromosome bands. 
B)  show a decreased number of chromosome bands. 
C)  are all associated with a specific defective phenotype. 
D)  indicate that carriers are mentally retarded. 
E)  are inherited in a codominant fashion. 
A)  show an increased number of chromosome bands. 
B)  show a decreased number of chromosome bands. 
C)  are all associated with a specific defective phenotype. 
D)  indicate that carriers are mentally retarded. 
E)  are inherited in a codominant fashion. E

Question 4

Nondisjunction of the sex chromosomes produces both Klinefelter syndrome (XXY) and Turner syndrome (XO), but among live births, 1 in 1,000 males is XXY, but only 1 in 10,000 females is XO. What mechanisms can account for this tenfold difference in frequency?

Accepted Answer

The tenfold difference in the frequency

Question 5

Amniocentesis is typically not perfomed on mothers over the age of 35.

Accepted Answer

A) True 
 B)False

Question 6

In the case of nondisjunction producing a trisomic condition, how might it be possible to determine in which parent this event occurred? Might it be possible to determine whether this event occurred in the first or second meiotic division?

Accepted Answer

In the case of nondisjunction producing

Question 7

Who are translocation carriers and in what sense are they high-risk individuals?

Accepted Answer

Translocation carriers are individuals w

Question 8

If nondisjunction takes place in one of the cells of the second meiotic division, the four products of meiosis will include

Accepted Answer

A)  two normal and two abnormal karyotypes. 
B)  four abnormal karyotypes. 
C)  three normal and one abnormal karyotype. 
D)  four normal karyotypes. 
E)  none of these. 
A)  two normal and two abnormal karyotypes. 
B)  four abnormal karyotypes. 
C)  three normal and one abnormal karyotype. 
D)  four normal karyotypes. 
E)  none of these.

Question 9

Amniocentesis and chorionic villus sampling are two methods of prenatal diagnosis. One important difference between these techniques is that

Accepted Answer

A)  chorionic villus sampling is more routinely prescribed. 
B)  amniocentesis can diagnose chromosome disorders, while chorionic villus sampling cannot. 
C)  chorionic villus sampling can be performed earlier than amniocentesis. 
D)  maternal risks are higher with chorionic villus sampling. 
E)  the risk of miscarriage is higher with amniocentesis than with chorionic villus sampling. 
A)  chorionic villus sampling is more routinely prescribed. 
B)  amniocentesis can diagnose chromosome disorders, while chorionic villus sampling cannot. 
C)  chorionic villus sampling can be performed earlier than amniocentesis. 
D)  maternal risks are higher with chorionic villus sampling. 
E)  the risk of miscarriage is higher with amniocentesis than with chorionic villus sampling.

Question 10

What would be the karyotypic designation of a female with trisomy for the X chromosome? ____________________

Accepted Answer

The answer of What would be the karyotypic designation of...

Question 11

The most precise prenatal diagnosis for detecting chromosomal abnormalities is __________.

Accepted Answer

chrorionic

Question 12

Which one of the following pairings of an aneuploidy and the syndrome it causes is incorrectly matched?

Accepted Answer

A)  X-chromosome monosomy (X and no Y) causes Turner syndrome. 
B)  X-chromosome trisomy causes Klinefelter syndrome. 
C)  Trisomy 21 causes Down syndrome. 
D)  Trisomy 13 causes Edwards syndrome. 
E)  Uniparental disomy causes Prader-Willi syndrome. 
A)  X-chromosome monosomy (X and no Y) causes Turner syndrome. 
B)  X-chromosome trisomy causes Klinefelter syndrome. 
C)  Trisomy 21 causes Down syndrome. 
D)  Trisomy 13 causes Edwards syndrome. 
E)  Uniparental disomy causes Prader-Willi syndrome.

Question 13

_______ describes a chromosome that has a centrally-placed centromere.

Accepted Answer

The answer of _______ describes a chromosome that has a...

Question 14

A balanced chromosome complement is necessary for normal development, with adverse consequences for additional or missing chromosomes or chromosome fragments. Use examples to show which is more harmful to the individual.

Accepted Answer

Balanced chromosome complement is necess

Question 15

Describe chromosomal deletions, inversions, and translocations. If an individual had an inversion on chromosome 12 and another had a deletion on chromosome 12, which would be more affected and why?

Accepted Answer

Chromosomal deletions, inversions, and t

Question 16

Monosomy for autosomes is lethal in humans. If an aborted male fetus had monosomy for chromosome 6, how would you designate (write) the karyotype? ____________________

Accepted Answer

The answer of Monosomy for autosomes is lethal in humans....

Question 17

Cell-free fetal DNA originates from the breakdown of fetal cells in the __________.

Accepted Answer

The answer of Cell-free fetal DNA originates from the breakdown...

Question 18

The risk for Down syndrome increases in situations where the

Accepted Answer

A)  mother is 20-29 years old. 
B)  father is 35-50 years old. 
C)  mother is 35-45 years old. 
D)  father is 20-29 years old. 
E)  both parents are 30-35 years old. 
A)  mother is 20-29 years old. 
B)  father is 35-50 years old. 
C)  mother is 35-45 years old. 
D)  father is 20-29 years old. 
E)  both parents are 30-35 years old.

Question 19

The effect of colcemid on cells is to stop division at anaphase.

Accepted Answer

A) True 
 B)False

Question 20

How many chromosomes are in a red blood cell taken from a normal person? ____________________

Accepted Answer

The answer of How many chromosomes are in a red...

A chromosome whose centromere is near one end is termed ____________________.

The region that divides a chromosome into two arms is the ______.

Fragile sites are chromosome locations that

Nondisjunction of the sex chromosomes produces both Klinefelter syndrome (XXY) and Turner syndrome (XO), but among live births, 1 in 1,000 males is XXY, but only 1 in 10,000 females is XO. What mechanisms can account for this tenfold difference in frequency?

Amniocentesis is typically not perfomed on mothers over the age of 35.

In the case of nondisjunction producing a trisomic condition, how might it be possible to determine in which parent this event occurred? Might it be possible to determine whether this event occurred in the first or second meiotic division?

Who are translocation carriers and in what sense are they high-risk individuals?

If nondisjunction takes place in one of the cells of the second meiotic division, the four products of meiosis will include

Amniocentesis and chorionic villus sampling are two methods of prenatal diagnosis. One important difference between these techniques is that

What would be the karyotypic designation of a female with trisomy for the X chromosome? ____________________

The most precise prenatal diagnosis for detecting chromosomal abnormalities is __________.

Which one of the following pairings of an aneuploidy and the syndrome it causes is incorrectly matched?

_______ describes a chromosome that has a centrally-placed centromere.

A balanced chromosome complement is necessary for normal development, with adverse consequences for additional or missing chromosomes or chromosome fragments. Use examples to show which is more harmful to the individual.

Describe chromosomal deletions, inversions, and translocations. If an individual had an inversion on chromosome 12 and another had a deletion on chromosome 12, which would be more affected and why?

Monosomy for autosomes is lethal in humans. If an aborted male fetus had monosomy for chromosome 6, how would you designate (write) the karyotype? ____________________

Cell-free fetal DNA originates from the breakdown of fetal cells in the __________.

The risk for Down syndrome increases in situations where the

The effect of colcemid on cells is to stop division at anaphase.

How many chromosomes are in a red blood cell taken from a normal person? ____________________

A Perspective on Human Genetics

Cells and Cell Division

Transmission of Genes From Generation to Generation

Pedigree Analysis in Human Genetics

Complex Patterns of Inheritance

Development and Sex Determination

DNA Structure and Chromosomal Organization

Gene Expression: From Genes to Proteins

From Proteins to Phenotypes

Mutation: the Source of Genetic Variation

Genes and Cancer

An Introduction to Genetic Technology

Biotechnology and Society

Genomes and Genomics

Reproductive Technology, Genetic Testing, and Gene Therapy

Genes and the Immune System

Genetics of Behavior

Population Genetics and Human Evolution

Filters

Exam 6: Cytogenetics: Karyotypes and Chromosome Aberrations

A chromosome whose centromere is near one end is termed ____________________.

The region that divides a chromosome into two arms is the ______.

Fragile sites are chromosome locations that

Nondisjunction of the sex chromosomes produces both Klinefelter syndrome (XXY) and Turner syndrome (XO), but among live births, 1 in 1,000 males is XXY, but only 1 in 10,000 females is XO. What mechanisms can account for this tenfold difference in frequency?

Amniocentesis is typically not perfomed on mothers over the age of 35.

In the case of nondisjunction producing a trisomic condition, how might it be possible to determine in which parent this event occurred? Might it be possible to determine whether this event occurred in the first or second meiotic division?

Who are translocation carriers and in what sense are they high-risk individuals?

If nondisjunction takes place in one of the cells of the second meiotic division, the four products of meiosis will include

Amniocentesis and chorionic villus sampling are two methods of prenatal diagnosis. One important difference between these techniques is that

What would be the karyotypic designation of a female with trisomy for the X chromosome? ____________________

The most precise prenatal diagnosis for detecting chromosomal abnormalities is __________.

Which one of the following pairings of an aneuploidy and the syndrome it causes is incorrectly matched?

_______ describes a chromosome that has a centrally-placed centromere.

A balanced chromosome complement is necessary for normal development, with adverse consequences for additional or missing chromosomes or chromosome fragments. Use examples to show which is more harmful to the individual.

Describe chromosomal deletions, inversions, and translocations. If an individual had an inversion on chromosome 12 and another had a deletion on chromosome 12, which would be more affected and why?

Monosomy for autosomes is lethal in humans. If an aborted male fetus had monosomy for chromosome 6, how would you designate (write) the karyotype? ____________________

Cell-free fetal DNA originates from the breakdown of fetal cells in the __________.

The risk for Down syndrome increases in situations where the

The effect of colcemid on cells is to stop division at anaphase.

How many chromosomes are in a red blood cell taken from a normal person? ____________________

A Perspective on Human Genetics

Cells and Cell Division

Transmission of Genes From Generation to Generation

Pedigree Analysis in Human Genetics

Complex Patterns of Inheritance

Development and Sex Determination

DNA Structure and Chromosomal Organization

Gene Expression: From Genes to Proteins

From Proteins to Phenotypes

Mutation: the Source of Genetic Variation

Genes and Cancer

An Introduction to Genetic Technology

Biotechnology and Society

Genomes and Genomics

Reproductive Technology, Genetic Testing, and Gene Therapy

Genes and the Immune System

Genetics of Behavior

Population Genetics and Human Evolution

Filters