Question 1

The enzyme that catalyzes the reaction ATP + D-glucose ? ADP + D-glucose-6-phosphate is:

Accepted Answer

A)  Glucose oxidase. 
B)  Lyase. 
C)  Hexokinase. 
D)  Mutase. 
A)  Glucose oxidase. 
B)  Lyase. 
C)  Hexokinase. 
D)  Mutase. C

Question 2

Glycolysis is:

Accepted Answer

A)  The conversion of glucose into lactate or pyruvate and then CO2 and H2O. 
B)  The conversion of glucose to glycogen for storage. 
C)  The breakdown of glycogen to form glucose and other intermediate products. 
D)  The formation of glucose from noncarbohydrate sources. 
A)  The conversion of glucose into lactate or pyruvate and then CO2 and H2O. 
B)  The conversion of glucose to glycogen for storage. 
C)  The breakdown of glycogen to form glucose and other intermediate products. 
D)  The formation of glucose from noncarbohydrate sources. A

Question 3

A patient's low glucose, increased insulin, and increased C-peptide is caused by:

Accepted Answer

A)  Glucagonoma. 
B)  Addison's disease. 
C)  Insulinoma. 
D)  Injection of exogenous insulin. 
A)  Glucagonoma. 
B)  Addison's disease. 
C)  Insulinoma. 
D)  Injection of exogenous insulin. C

Question 4

Which of the following 2-hour glucose results would be classified as impaired glucose tolerance?

Accepted Answer

A)  125 mg/dL 
B)  135 mg/dL 
C)  160 mg/dL 
D)  210 mg/dL 
A)  125 mg/dL 
B)  135 mg/dL 
C)  160 mg/dL 
D)  210 mg/dL

Question 5

All of the following are confirmatory of diabetes mellitus EXCEPT:

Accepted Answer

A)  Fasting glucose greater than 126 mg/dL. 
B)  Urine glucose greater than 300 mg/dL 
C)  2-hour postprandial glucose greater than 200 mg/dl. 
D)  1- and 2-hour glucose tolerance values greater than 200 mg/dL. 
A)  Fasting glucose greater than 126 mg/dL. 
B)  Urine glucose greater than 300 mg/dL 
C)  2-hour postprandial glucose greater than 200 mg/dl. 
D)  1- and 2-hour glucose tolerance values greater than 200 mg/dL.

Question 6

Select the enzyme that is most specific for ?-D glucose.

Accepted Answer

A)  Phosphohexisomerase 
B)  Hexokinase 
C)  Glucose oxidase 
D)  Glucose dehydrogenase 
A)  Phosphohexisomerase 
B)  Hexokinase 
C)  Glucose oxidase 
D)  Glucose dehydrogenase

Question 7

What type of hypoglycemia is exhibited 8 hours after a meal?

Accepted Answer

A)  Reactive 
B)  Fasting 
C)  Alimentary 
D)  None of the above 
A)  Reactive 
B)  Fasting 
C)  Alimentary 
D)  None of the above

Question 8

In a specimen collected for plasma glucose analysis, sodium fluoride:

Accepted Answer

A)  Serves as a coenzyme of hexokinase. 
B)  Prevents reactivity of non glucose reducing substances. 
C)  Precipitates protein. 
D)  Inhibits glycolysis. 
A)  Serves as a coenzyme of hexokinase. 
B)  Prevents reactivity of non glucose reducing substances. 
C)  Precipitates protein. 
D)  Inhibits glycolysis.

Question 9

The glucose concentration in normal cerebrospinal fluid is:

Accepted Answer

A)  Usually less than 30 mg/dL. 
B)  60-75% of the plasma glucose concentration. 
C)  Equal to the plasma glucose concentration. 
D)  Usually greater than 100 mg/dL. 
A)  Usually less than 30 mg/dL. 
B)  60-75% of the plasma glucose concentration. 
C)  Equal to the plasma glucose concentration. 
D)  Usually greater than 100 mg/dL.

Question 10

Complications of diabetes mellitus include all of the following EXCEPT:

Accepted Answer

A)  Heart disease and stroke. 
B)  Neuropathy. 
C)  Nephropathy. 
D)  Hepatitis. 
A)  Heart disease and stroke. 
B)  Neuropathy. 
C)  Nephropathy. 
D)  Hepatitis.

Question 11

All of the following are associated with gestational diabetes EXCEPT:

Accepted Answer

A)  It converts to diabetes mellitus after pregnancy in 30-60% of patients. 
B)  Is diagnosed using the same glucose tolerance criteria as in nonpregnant women. 
C)  Is defined as glucose intolerance during pregnancy. 
D)  Associated with increased fetal risk. 
A)  It converts to diabetes mellitus after pregnancy in 30-60% of patients. 
B)  Is diagnosed using the same glucose tolerance criteria as in nonpregnant women. 
C)  Is defined as glucose intolerance during pregnancy. 
D)  Associated with increased fetal risk.

Question 12

In the Hexokinase method for glucose determinations, the actual end product measured is the:

Accepted Answer

A)  Amount of hydrogen peroxide produced. 
B)  NADPH + H+ produced from the reduction of NADP. 
C)  Amount of glucose combined with bromcresol purple. 
D)  Condensation of glucose with an aromatic amine. 
A)  Amount of hydrogen peroxide produced. 
B)  NADPH + H+ produced from the reduction of NADP. 
C)  Amount of glucose combined with bromcresol purple. 
D)  Condensation of glucose with an aromatic amine.

Question 13

Which statement regarding glycosylated hemoglobin is TRUE?

Accepted Answer

A)  It has a sugar attached to the N-terminal valine of the ?-chain of the hemoglobin molecule. 
B)  Is dependent upon the time averaged blood glucose over the lifespan of the RBC. 
C)  Levels below 7% indicate adequate regulation for 8-12 weeks prior to sampling. 
D)  All of the above 
A)  It has a sugar attached to the N-terminal valine of the ?-chain of the hemoglobin molecule. 
B)  Is dependent upon the time averaged blood glucose over the lifespan of the RBC. 
C)  Levels below 7% indicate adequate regulation for 8-12 weeks prior to sampling. 
D)  All of the above

Question 14

Of the following blood glucose levels, which would you expect to result in glucose in the urine?

Accepted Answer

A)  70 mg/dL 
B)  100 mg/dL 
C)  120 mg/dL 
D)  200 mg/dL 
A)  70 mg/dL 
B)  100 mg/dL 
C)  120 mg/dL 
D)  200 mg/dL

Question 15

A patient with an insulinoma may exhibit dizziness and fainting attributable to:

Accepted Answer

A)  Hypoglycemia. 
B)  Hyperglycemia. 
C)  Ketosis. 
D)  Acidosis. 
A)  Hypoglycemia. 
B)  Hyperglycemia. 
C)  Ketosis. 
D)  Acidosis.

Question 16

If a patient's serum glucose is 100 mg/dL, what would you expect the cerebrospinal fluid glucose to read?

Accepted Answer

A)  45 mg/dL 
B)  68 mg/dL 
C)  85 mg/dL 
D)  95 mg/dL 
A)  45 mg/dL 
B)  68 mg/dL 
C)  85 mg/dL 
D)  95 mg/dL

Question 17

Glucose concentration in serum is:

Accepted Answer

A)  Higher than the concentration in whole blood. 
B)  Lower than the concentration in whole blood. 
C)  Equal to the concentration in whole blood. 
D)  Unable to predict-variable. 
A)  Higher than the concentration in whole blood. 
B)  Lower than the concentration in whole blood. 
C)  Equal to the concentration in whole blood. 
D)  Unable to predict-variable.

Question 18

The following glucose tolerance test values are indicative of what state?
Fasting: 85 mg/dL
1/2 hour: 135 mg/dL
1 hour: 139 mg/dL
2 hour: 130 mg/dL

Accepted Answer

A)  Normal 
B)  Diabetes mellitus 
C)  Addison's disease 
D)  Hyperinsulinism 
A)  Normal 
B)  Diabetes mellitus 
C)  Addison's disease 
D)  Hyperinsulinism

Question 19

Glycogen is stored in the:

Accepted Answer

A)  Pancreas. 
B)  Liver. 
C)  Spleen. 
D)  Gall bladder. 
A)  Pancreas. 
B)  Liver. 
C)  Spleen. 
D)  Gall bladder.

Question 20

Instructions for patients preparing for a glucose tolerance tests include all of the following EXCEPT:

Accepted Answer

A)  No food 10 hours before and during the test. 
B)  Patient must be ambulatory for 3 days prior to the test. 
C)  Carbohydrate intake must be at least 150g/day for 3 days prior to the test. 
D)  Caffeine and smoking are permitted before and during the test. 
A)  No food 10 hours before and during the test. 
B)  Patient must be ambulatory for 3 days prior to the test. 
C)  Carbohydrate intake must be at least 150g/day for 3 days prior to the test. 
D)  Caffeine and smoking are permitted before and during the test.

Exam 7: Carbohydrates

The enzyme that catalyzes the reaction ATP + D-glucose ? ADP + D-glucose-6-phosphate is:

Glycolysis is:

A patient's low glucose, increased insulin, and increased C-peptide is caused by:

Which of the following 2-hour glucose results would be classified as impaired glucose tolerance?

All of the following are confirmatory of diabetes mellitus EXCEPT:

Select the enzyme that is most specific for ?-D glucose.

What type of hypoglycemia is exhibited 8 hours after a meal?

In a specimen collected for plasma glucose analysis, sodium fluoride:

The glucose concentration in normal cerebrospinal fluid is:

Complications of diabetes mellitus include all of the following EXCEPT:

All of the following are associated with gestational diabetes EXCEPT:

In the Hexokinase method for glucose determinations, the actual end product measured is the:

Which statement regarding glycosylated hemoglobin is TRUE?

Of the following blood glucose levels, which would you expect to result in glucose in the urine?

A patient with an insulinoma may exhibit dizziness and fainting attributable to:

If a patient's serum glucose is 100 mg/dL, what would you expect the cerebrospinal fluid glucose to read?

Glucose concentration in serum is:

The following glucose tolerance test values are indicative of what state? Fasting: 85 mg/dL 1/2 hour: 135 mg/dL 1 hour: 139 mg/dL 2 hour: 130 mg/dL

Glycogen is stored in the:

Instructions for patients preparing for a glucose tolerance tests include all of the following EXCEPT:

Laboratory Basics

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