Question 1

Given the following ABO phenotyping data:  
What could be a plausible explanation for this discrepancy?

Accepted Answer

A)  T-activation of red cells 
B)  Group O blood products given to group A 
C)  Rouleaux formation 
D)  Positive direct antiglobulin test 
A)  T-activation of red cells 
B)  Group O blood products given to group A 
C)  Rouleaux formation 
D)  Positive direct antiglobulin test B

Question 2

Match the immunodominant sugar that corresponds to the ABO system group or antigen.
-Group B

Accepted Answer

A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above 
A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above A

Question 3

Most "naturally occurring" ABO system antibodies fall into which class?

Accepted Answer

A)  IgA 
B)  IgM 
C)  IgE 
D)  IgG 
A)  IgA 
B)  IgM 
C)  IgE 
D)  IgG B

Question 4

Approximately what is the percentage of individuals who demonstrate H in their saliva?

Accepted Answer

A)  15% 
B)  50% 
C)  80% 
D)  98% 
A)  15% 
B)  50% 
C)  80% 
D)  98%

Question 5

The test procedure that combines patient's serum with commercial A1 and B reagent red cells is called:

Accepted Answer

A)  ABO forward grouping. 
B)  ABO reverse grouping. 
C)  antibody screen. 
D)  antibody panel. 
A)  ABO forward grouping. 
B)  ABO reverse grouping. 
C)  antibody screen. 
D)  antibody panel.

Question 6

Match the immunodominant sugar that corresponds to the ABO system group or antigen.
-Bombay

Accepted Answer

A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above 
A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above

Question 7

Which of the following situations is most likely to cause intravascular hemolysis when an incompatible transfusion is given?

Accepted Answer

A)  Group B packed cells to a group O recipient 
B)  Group A packed red cells to a group AB recipient 
C)  Group AB plasma to a group A recipient 
D)  Group AB plasma to a group O recipient 
A)  Group B packed cells to a group O recipient 
B)  Group A packed red cells to a group AB recipient 
C)  Group AB plasma to a group A recipient 
D)  Group AB plasma to a group O recipient

Question 8

A patient's red cells are agglutinated by anti-B, but not by anti-A. This person would have which of the following ABO phenotypes?

Accepted Answer

A)  Group B 
B)  Group O 
C)  Group AB 
D)  Group A 
A)  Group B 
B)  Group O 
C)  Group AB 
D)  Group A

Question 9

To distinguish between an A1 and A2 blood type, which reagent is used?

Accepted Answer

A)  Ulex europeaus lectin 
B)  Anti-A,B 
C)  Monoclonal anti-A 
D)  Dolichos biflorus lectin 
A)  Ulex europeaus lectin 
B)  Anti-A,B 
C)  Monoclonal anti-A 
D)  Dolichos biflorus lectin

Question 10

A blood sample from a 90-year-old man was submitted to the blood bank for a type and screen before surgery. The forward type demonstrates as a group A, whereas the reverse type appears to be group AB. The most likely cause of the discrepancy is:

Accepted Answer

A)  contaminated reagent antisera. 
B)  rouleaux formation. 
C)  that the patient has autoantibodies. 
D)  that patient has low-titer isoagglutinins. 
A)  contaminated reagent antisera. 
B)  rouleaux formation. 
C)  that the patient has autoantibodies. 
D)  that patient has low-titer isoagglutinins.

Question 11

Why is it sometimes necessary to distinguish A1 and A2 blood types?

Accepted Answer

A)  To resolve a discrepancy between the forward and reverse typing 
B)  To prevent A1 recipients from receiving A2 blood 
C)  To determine the secretor status of group A individuals 
D)  To prevent hemolytic disease of the newborn 
A)  To resolve a discrepancy between the forward and reverse typing 
B)  To prevent A1 recipients from receiving A2 blood 
C)  To determine the secretor status of group A individuals 
D)  To prevent hemolytic disease of the newborn

Question 12

Select the appropriate strategy if the results of red cell and serum testing in the ABO typing procedure have negative agglutination reactions.

Accepted Answer

A)  Wash patient cells with warm saline. 
B)  Use polyclonal typing reagents. 
C)  Perform an autocontrol. 
D)  Incubate tubes at room temperature or 4° C with an autocontrol. 
A)  Wash patient cells with warm saline. 
B)  Use polyclonal typing reagents. 
C)  Perform an autocontrol. 
D)  Incubate tubes at room temperature or 4° C with an autocontrol.

Question 13

What substances are found in the saliva of a group A person who also inherited the secretor gene?

Accepted Answer

A)  A, H 
B)  H 
C)  A, Se 
D)  A, B, H 
A)  A, H 
B)  H 
C)  A, Se 
D)  A, B, H

Question 14

Match the immunodominant sugar that corresponds to the ABO system group or antigen.
-H antigen

Accepted Answer

A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above 
A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above

Question 15

Match the immunodominant sugar that corresponds to the ABO system group or antigen.
-Group O

Accepted Answer

A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above 
A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above

Question 16

What would be the agglutination reaction of red cells from a Bombay phenotype with anti-H lectin?

Accepted Answer

A)  Strong 4+ 
B)  Mixed field 
C)  Weak 1+ 
D)  Negative 
A)  Strong 4+ 
B)  Mixed field 
C)  Weak 1+ 
D)  Negative

Question 17

Match the immunodominant sugar that corresponds to the ABO system group or antigen.
-Group A

Accepted Answer

A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above 
A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above

Question 18

What percentage of the group A population are type A2?

Accepted Answer

A)  1% 
B)  10% 
C)  20% 
D)  35% 
A)  1% 
B)  10% 
C)  20% 
D)  35%

Question 19

According to Landsteiner's rule, what ABO antibody will be detected in a group A individual's serum?

Accepted Answer

A)  Anti-A 
B)  Anti-B 
C)  Anti-A,B 
D)  None 
A)  Anti-A 
B)  Anti-B 
C)  Anti-A,B 
D)  None

Question 20

The subgroup of A with the least amount of A antigen is:

Accepted Answer

A)  A3. 
B)  Ax. 
C)  A2. 
D)  Ael. 
A)  A3. 
B)  Ax. 
C)  A2. 
D)  Ael.

Given the following ABO phenotyping data: What could be a plausible explanation for this discrepancy?

Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Group B

Most "naturally occurring" ABO system antibodies fall into which class?

Approximately what is the percentage of individuals who demonstrate H in their saliva?

The test procedure that combines patient's serum with commercial A₁ and B reagent red cells is called:

Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Bombay

Which of the following situations is most likely to cause intravascular hemolysis when an incompatible transfusion is given?

A patient's red cells are agglutinated by anti-B, but not by anti-A. This person would have which of the following ABO phenotypes?

To distinguish between an A₁ and A₂blood type, which reagent is used?

A blood sample from a 90-year-old man was submitted to the blood bank for a type and screen before surgery. The forward type demonstrates as a group A, whereas the reverse type appears to be group AB. The most likely cause of the discrepancy is:

Why is it sometimes necessary to distinguish A₁ and A₂ blood types?

Select the appropriate strategy if the results of red cell and serum testing in the ABO typing procedure have negative agglutination reactions.

What substances are found in the saliva of a group A person who also inherited the secretor gene?

Match the immunodominant sugar that corresponds to the ABO system group or antigen. -H antigen

Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Group O

What would be the agglutination reaction of red cells from a Bombay phenotype with anti-H lectin?

Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Group A

What percentage of the group A population are type A₂?

According to Landsteiner's rule, what ABO antibody will be detected in a group A individual's serum?

The subgroup of A with the least amount of A antigen is:

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications in Immunohematology

Genetic Principles in Blood Banking

Rh Blood Group System

Other Blood Group Systems

Antibody Detection and Identification

Compatibility Testing

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry

Safety Issues in the Blood Bank

Filters

Exam 4: Abo and H Blood Group Systems and Secretor Status

Given the following ABO phenotyping data: What could be a plausible explanation for this discrepancy?

Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Group B

Most "naturally occurring" ABO system antibodies fall into which class?

Approximately what is the percentage of individuals who demonstrate H in their saliva?

The test procedure that combines patient's serum with commercial A1 and B reagent red cells is called:

Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Bombay

Which of the following situations is most likely to cause intravascular hemolysis when an incompatible transfusion is given?

A patient's red cells are agglutinated by anti-B, but not by anti-A. This person would have which of the following ABO phenotypes?

To distinguish between an A1 and A2 blood type, which reagent is used?

A blood sample from a 90-year-old man was submitted to the blood bank for a type and screen before surgery. The forward type demonstrates as a group A, whereas the reverse type appears to be group AB. The most likely cause of the discrepancy is:

Why is it sometimes necessary to distinguish A1 and A2 blood types?

Select the appropriate strategy if the results of red cell and serum testing in the ABO typing procedure have negative agglutination reactions.

What substances are found in the saliva of a group A person who also inherited the secretor gene?

Match the immunodominant sugar that corresponds to the ABO system group or antigen. -H antigen

Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Group O

What would be the agglutination reaction of red cells from a Bombay phenotype with anti-H lectin?

Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Group A

What percentage of the group A population are type A2?

According to Landsteiner's rule, what ABO antibody will be detected in a group A individual's serum?

The subgroup of A with the least amount of A antigen is:

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications in Immunohematology

Genetic Principles in Blood Banking

Rh Blood Group System

Other Blood Group Systems

Antibody Detection and Identification

Compatibility Testing

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry

Safety Issues in the Blood Bank

Filters

The test procedure that combines patient's serum with commercial A₁ and B reagent red cells is called:

To distinguish between an A₁ and A₂blood type, which reagent is used?

Why is it sometimes necessary to distinguish A₁ and A₂ blood types?

What percentage of the group A population are type A₂?