Exam 1: Immunology: Basic Principles and Applications in the Blood Bank

Select the cell involved in the clearance of viral infected cells, tumor cells, and foreign-tissue grafts.

Which of the following will cause an antigen to elicit a greater immune response?

What portion of the antibody molecule binds to receptors on macrophages and assists in the removal of antibody bound to red cells?

Select the antiglobulin test that best fits the description below. -Tests for certain clinical conditions such as hemolytic disease of the newborn and autoimmune hemolytic anemia

What immunoglobulin class reacts best at room temperature at immediate spin?

Select the region of the antibody molecule responsible for imparting unique antibody specificity.

The purpose of adding antibody-sensitized red cells following the antiglobulin test is to:

An antibody with a specificity other than to one's own cells or tissue that is stimulated by transfusion or pregnancy is termed an:

Human leukocyte antigen antibodies are often stimulated following a patient's repeated transfusions of platelets. This poor response to platelet transfusion is known as:

Select the term that is associated with the B-cell response to antigens.

Select the antiglobulin test that best fits the description below. -Incubation step is not necessary

What cells are also known as antigen-presenting cells?

What is the potential effect in a tube agglutination test if a red cell suspension with a concentration greater than 5% is used?

What immunoglobulin class is capable of crossing the placenta?

In a serologic test, the term prozone is also known as:

Which of the following red cell antigens do proteolytic enzymes destroy?

Select the antiglobulin test that best fits the description below. -Detects IgG or complement-coated red cells

What immunoglobulin class reacts best by antiglobulin testing?

Which of the following is responsible for the activation of the classic pathway of complement?

Select the antiglobulin test that best fits the description below. -Requires washing the cells several times before the addition of antihuman globulin reagent