Question 1

An anaphylactic transfusion reaction is caused by __________ antibodies.

Accepted Answer

A)  IgA 
B)  IgG 
C)  IgE 
D)  All of the above 
A)  IgA 
B)  IgG 
C)  IgE 
D)  All of the above A

Question 2

Ten days after the transfusion of 2 units, a patient had a 2 g/dL drop in hemoglobin and was slightly jaundiced. No evidence of bleeding was found. What tests would be helpful in determining whether the patient is experiencing a delayed hemolytic transfusion reaction?

Accepted Answer

A)  Culture the donor unit. 
B)  Compare pretransfusion and posttransfusion ABO and D typing. 
C)  Perform hepatitis B surface antigen test. 
D)  Perform an antibody screen on the posttransfusion sample. 
A)  Culture the donor unit. 
B)  Compare pretransfusion and posttransfusion ABO and D typing. 
C)  Perform hepatitis B surface antigen test. 
D)  Perform an antibody screen on the posttransfusion sample. D

Question 3

Posttransfusion purpura is caused by:

Accepted Answer

A)  red cell antibodies. 
B)  white cell antibodies. 
C)  platelet antibodies. 
D)  bacterial contamination. 
A)  red cell antibodies. 
B)  white cell antibodies. 
C)  platelet antibodies. 
D)  bacterial contamination. C

Question 4

A patient is observed to have a rise in temperature and chills during a transfusion. The transfusion is stopped, and a posttransfusion blood sample is carefully drawn. On receipt of this postreaction sample, the transfusion service should immediately:

Accepted Answer

A)  observe the color of serum and perform an antibody screen. 
B)  observe the color of serum and perform a direct antiglobulin test. 
C)  perform an antibody screen and a direct antiglobulin test. 
D)  perform an antibody screen and a crossmatch. 
A)  observe the color of serum and perform an antibody screen. 
B)  observe the color of serum and perform a direct antiglobulin test. 
C)  perform an antibody screen and a direct antiglobulin test. 
D)  perform an antibody screen and a crossmatch.

Question 5

Match the transfusion reaction with the description that best fits.
-Transfusion-related acute lung injury

Accepted Answer

A) Prevented by leukoreduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly 
A) Prevented by leukoreduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly

Question 6

Which of the following blood group systems has been implicated in transfusion reactions on the first exposure to incompatible red blood cells?

Accepted Answer

A)  Rh 
B)  Kell 
C)  Kidd 
D)  ABO 
A)  Rh 
B)  Kell 
C)  Kidd 
D)  ABO

Question 7

Match the transfusion reaction with the description that best fits.
-Febrile, nonhemolytic

Accepted Answer

A) Prevented by leukoreduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly 
A) Prevented by leukoreduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly

Question 8

A hemolytic reaction to red blood cells can be caused by which of the following nonimmune mechanisms?

Accepted Answer

A)  Incompatible intravenous solutions mixed with the unit 
B)  Improper storage of the unit 
C)  Bacterial contamination of the unit 
D)  All of the above 
A)  Incompatible intravenous solutions mixed with the unit 
B)  Improper storage of the unit 
C)  Bacterial contamination of the unit 
D)  All of the above

Question 9

Which of the following is necessary to prevent an anaphylactic reaction due to a known IgA antibody in a patient?

Accepted Answer

A)  All red blood cell units should be irradiated. 
B)  Red blood cell units should be washed. 
C)  All blood components should be leukoreduced. 
D)  Patient should be given antihistamine before transfusion. 
A)  All red blood cell units should be irradiated. 
B)  Red blood cell units should be washed. 
C)  All blood components should be leukoreduced. 
D)  Patient should be given antihistamine before transfusion.

Question 10

Which of the following transfusion reactions has the highest incidence?

Accepted Answer

A)  Hemolytic reactions due to ABO incompatibility 
B)  Urticarial 
C)  Graft-versus-host disease 
D)  Transfusion-related acute lung injury 
A)  Hemolytic reactions due to ABO incompatibility 
B)  Urticarial 
C)  Graft-versus-host disease 
D)  Transfusion-related acute lung injury

Question 11

What organ of the recipient's body is involved in a transfusion-related acute lung injury transfusion reaction?

Accepted Answer

A)  Heart 
B)  Lung 
C)  Liver 
D)  Brain 
A)  Heart 
B)  Lung 
C)  Liver 
D)  Brain

Question 12

A 44-year-old woman has a hemoglobin level of 6.1 g/dL. White blood cell and platelet counts are within normal levels. The patient is group O D-negative with a negative antibody screen. Crossmatches are compatible. However, 15 minutes after the first transfusion is started, she experiences erythema and hives. What type of transfusion reaction is occurring?

Accepted Answer

A)  Urticarial 
B)  Febrile nonhemolytic 
C)  Delayed hemolytic 
D)  Acute hemolytic 
A)  Urticarial 
B)  Febrile nonhemolytic 
C)  Delayed hemolytic 
D)  Acute hemolytic

Question 13

Administration of whole blood to a patient with cardiac insufficiency could result in which of the following transfusion reactions?

Accepted Answer

A)  Delayed hemolytic reaction 
B)  Transfusion-related acute lung injury 
C)  Circulatory overload 
D)  Febrile nonhemolytic reaction 
A)  Delayed hemolytic reaction 
B)  Transfusion-related acute lung injury 
C)  Circulatory overload 
D)  Febrile nonhemolytic reaction

Question 14

Which blood product is recommended for transfusions to individuals with a history of febrile nonhemolytic transfusion reactions?

Accepted Answer

A)  Leukocyte-reduced red blood cells 
B)  Packed red blood cells 
C)  Frozen red blood cells 
D)  Whole blood 
A)  Leukocyte-reduced red blood cells 
B)  Packed red blood cells 
C)  Frozen red blood cells 
D)  Whole blood

Question 15

A patient was identified as having cardiac insufficiency that needed a red blood cell transfusion. How should the transfusion be administered?

Accepted Answer

A)  The red blood cell unit should be transfused slowly over a 4-hour period. 
B)  The unit should be transfused as whole blood. 
C)  Diuretics should be administered with the unit. 
D)  Transfusion should be avoided. 
A)  The red blood cell unit should be transfused slowly over a 4-hour period. 
B)  The unit should be transfused as whole blood. 
C)  Diuretics should be administered with the unit. 
D)  Transfusion should be avoided.

Question 16

Match the transfusion reaction with the description that best fits.
-Delayed hemolytic

Accepted Answer

A) Prevented by leukoreduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly 
A) Prevented by leukoreduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly

Question 17

Match the transfusion reaction with the description that best fits.
-Acute hemolytic

Accepted Answer

A) Prevented by leukoreduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly 
A) Prevented by leukoreduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly

Question 18

In what circumstance would a direct antiglobulin test be negative in the presence of a hemolytic process?

Accepted Answer

A)  Bacterial contamination of the unit 
B)  Medications that were administered with the unit 
C)  Red blood cell unit transfused quickly through a leukopoor filter 
D)  All of the above 
A)  Bacterial contamination of the unit 
B)  Medications that were administered with the unit 
C)  Red blood cell unit transfused quickly through a leukopoor filter 
D)  All of the above

Question 19

Match the transfusion reaction with the description that best fits.
-Urticarial

Accepted Answer

A) Prevented by leukoreduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly 
A) Prevented by leukoreduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly

Question 20

Match the transfusion reaction with the description that best fits.
-Graft-versus-host disease

Accepted Answer

A) Prevented by leukoreduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly 
A) Prevented by leukoreduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly

An anaphylactic transfusion reaction is caused by __________ antibodies.

Ten days after the transfusion of 2 units, a patient had a 2 g/dL drop in hemoglobin and was slightly jaundiced. No evidence of bleeding was found. What tests would be helpful in determining whether the patient is experiencing a delayed hemolytic transfusion reaction?

Posttransfusion purpura is caused by:

A patient is observed to have a rise in temperature and chills during a transfusion. The transfusion is stopped, and a posttransfusion blood sample is carefully drawn. On receipt of this postreaction sample, the transfusion service should immediately:

Match the transfusion reaction with the description that best fits. -Transfusion-related acute lung injury

Which of the following blood group systems has been implicated in transfusion reactions on the first exposure to incompatible red blood cells?

Match the transfusion reaction with the description that best fits. -Febrile, nonhemolytic

A hemolytic reaction to red blood cells can be caused by which of the following nonimmune mechanisms?

Which of the following is necessary to prevent an anaphylactic reaction due to a known IgA antibody in a patient?

Which of the following transfusion reactions has the highest incidence?

What organ of the recipient's body is involved in a transfusion-related acute lung injury transfusion reaction?

Administration of whole blood to a patient with cardiac insufficiency could result in which of the following transfusion reactions?

Which blood product is recommended for transfusions to individuals with a history of febrile nonhemolytic transfusion reactions?

A patient was identified as having cardiac insufficiency that needed a red blood cell transfusion. How should the transfusion be administered?

Match the transfusion reaction with the description that best fits. -Delayed hemolytic

Match the transfusion reaction with the description that best fits. -Acute hemolytic

In what circumstance would a direct antiglobulin test be negative in the presence of a hemolytic process?

Match the transfusion reaction with the description that best fits. -Urticarial

Match the transfusion reaction with the description that best fits. -Graft-versus-host disease

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications in Immunohematology

Genetic Principles in Blood Banking

Abo and H Blood Group Systems and Secretor Status

Rh Blood Group System

Other Blood Group Systems

Antibody Detection and Identification

Compatibility Testing

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Hemolytic Disease of the Fetus and Newborn

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry

Safety Issues in the Blood Bank

Filters

Exam 12: Adverse Complications of Transfusions

An anaphylactic transfusion reaction is caused by __________ antibodies.

Ten days after the transfusion of 2 units, a patient had a 2 g/dL drop in hemoglobin and was slightly jaundiced. No evidence of bleeding was found. What tests would be helpful in determining whether the patient is experiencing a delayed hemolytic transfusion reaction?

Posttransfusion purpura is caused by:

A patient is observed to have a rise in temperature and chills during a transfusion. The transfusion is stopped, and a posttransfusion blood sample is carefully drawn. On receipt of this postreaction sample, the transfusion service should immediately:

Match the transfusion reaction with the description that best fits. -Transfusion-related acute lung injury

Which of the following blood group systems has been implicated in transfusion reactions on the first exposure to incompatible red blood cells?

Match the transfusion reaction with the description that best fits. -Febrile, nonhemolytic

A hemolytic reaction to red blood cells can be caused by which of the following nonimmune mechanisms?

Which of the following is necessary to prevent an anaphylactic reaction due to a known IgA antibody in a patient?

Which of the following transfusion reactions has the highest incidence?

What organ of the recipient's body is involved in a transfusion-related acute lung injury transfusion reaction?

Administration of whole blood to a patient with cardiac insufficiency could result in which of the following transfusion reactions?

Which blood product is recommended for transfusions to individuals with a history of febrile nonhemolytic transfusion reactions?

A patient was identified as having cardiac insufficiency that needed a red blood cell transfusion. How should the transfusion be administered?

Match the transfusion reaction with the description that best fits. -Delayed hemolytic

Match the transfusion reaction with the description that best fits. -Acute hemolytic

In what circumstance would a direct antiglobulin test be negative in the presence of a hemolytic process?

Match the transfusion reaction with the description that best fits. -Urticarial

Match the transfusion reaction with the description that best fits. -Graft-versus-host disease

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications in Immunohematology

Genetic Principles in Blood Banking

Abo and H Blood Group Systems and Secretor Status

Rh Blood Group System

Other Blood Group Systems

Antibody Detection and Identification

Compatibility Testing

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Hemolytic Disease of the Fetus and Newborn

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry

Safety Issues in the Blood Bank

Filters