Question 1

An advantage of the polymerase chain reaction for viral marker testing is:

Accepted Answer

A)  it is quicker to perform than most other tests. 
B)  it is more cost effective than traditional test methods. 
C)  a small amount of DNA or RNA can be detected. 
D)  cross-contamination of samples is not a problem. 
A)  it is quicker to perform than most other tests. 
B)  it is more cost effective than traditional test methods. 
C)  a small amount of DNA or RNA can be detected. 
D)  cross-contamination of samples is not a problem. C

Question 2

If anti-M was reacted with red cells that are M+N+, how would they compare with red cells that are M+N-?

Accepted Answer

A)  Stronger 
B)  Weaker 
C)  The same 
D)  Varies with the method 
A)  Stronger 
B)  Weaker 
C)  The same 
D)  Varies with the method B

Question 3

Match the terms below with the definition that best fits.
-Having two or more alleles at a given gene locus

Accepted Answer

A) Haplotypes 
B) Recessive 
C) Amorphic genes 
D) Codominant genes 
E) Polymorphic 
A) Haplotypes 
B) Recessive 
C) Amorphic genes 
D) Codominant genes 
E) Polymorphic E

Question 4

Match the term with the definition that best fits.
-DNA fragments produced by enzymatic cleavage at specific recognition sites

Accepted Answer

A) Restriction fragment-length polymorphism 
B) Polymerase chain reaction 
C) Hybridization 
D) Probe 
E) Amplicon 
A) Restriction fragment-length polymorphism 
B) Polymerase chain reaction 
C) Hybridization 
D) Probe 
E) Amplicon

Question 5

Match the terms below with the definition that best fits.
-When a gene product is expressed only when it is inherited by both parents

Accepted Answer

A) Haplotypes 
B) Recessive 
C) Amorphic genes 
D) Codominant genes 
E) Polymorphic 
A) Haplotypes 
B) Recessive 
C) Amorphic genes 
D) Codominant genes 
E) Polymorphic

Question 6

If two traits were found to occur higher in a population together than each occurs separately, they may be linked. This would suggest that:

Accepted Answer

A)  they are found far apart on the same chromosome. 
B)  they are inherited on different chromosomes. 
C)  crossover has occurred. 
D)  the genes are close together on the same chromosome. 
A)  they are found far apart on the same chromosome. 
B)  they are inherited on different chromosomes. 
C)  crossover has occurred. 
D)  the genes are close together on the same chromosome.

Question 7

The children of an AB mother and a B father could phenotype as all of the following except:

Accepted Answer

A)  O. 
B)  A. 
C)  B. 
D)  AB. 
A)  O. 
B)  A. 
C)  B. 
D)  AB.

Question 8

A person whose red cells type as M+, N+ with antisera would be:

Accepted Answer

A)  a homozygote. 
B)  a heterozygote. 
C)  unable to be determined without family studies. 
D)  linked. 
A)  a homozygote. 
B)  a heterozygote. 
C)  unable to be determined without family studies. 
D)  linked.

Question 9

A father carries the Xga blood group trait and passes it on to all of his daughters but to none of his sons. What type of inheritance pattern does this demonstrate?

Accepted Answer

A)  X-linked dominant 
B)  X-linked recessive 
C)  Autosomal dominant 
D)  Autosomal recessive 
A)  X-linked dominant 
B)  X-linked recessive 
C)  Autosomal dominant 
D)  Autosomal recessive

Question 10

When an individual is said to be group A, it refers to the individual's:

Accepted Answer

A)  alleles. 
B)  haplotype. 
C)  genotype. 
D)  phenotype. 
A)  alleles. 
B)  haplotype. 
C)  genotype. 
D)  phenotype.

Question 11

Of the following markers that can be used to test for paternity, which marker provides the most useful statistical value?

Accepted Answer

A)  Human leukocyte antigen typing 
B)  D antigens 
C)  ABO system antigens 
D)  The Kidd system (Jka, Jkb) 
A)  Human leukocyte antigen typing 
B)  D antigens 
C)  ABO system antigens 
D)  The Kidd system (Jka, Jkb)

Question 12

Match the term with the definition that best fits.
-The binding of two complementary pairs of DNA

Accepted Answer

A) Restriction fragment-length polymorphism 
B) Polymerase chain reaction 
C) Hybridization 
D) Probe 
E) Amplicon 
A) Restriction fragment-length polymorphism 
B) Polymerase chain reaction 
C) Hybridization 
D) Probe 
E) Amplicon

Question 13

Match the terms below with the definition that best fits.
-Equal expression of two different inherited genes as in most blood group systems

Accepted Answer

A) Haplotypes 
B) Recessive 
C) Amorphic genes 
D) Codominant genes 
E) Polymorphic 
A) Haplotypes 
B) Recessive 
C) Amorphic genes 
D) Codominant genes 
E) Polymorphic

Question 14

Match the term with the definition that best fits.
-Amplified target sequences of DNA produced by polymerase chain reaction

Accepted Answer

A) Restriction fragment-length polymorphism 
B) Polymerase chain reaction 
C) Hybridization 
D) Probe 
E) Amplicon 
A) Restriction fragment-length polymorphism 
B) Polymerase chain reaction 
C) Hybridization 
D) Probe 
E) Amplicon

Question 15

When using the Hardy-Weinberg equation to calculate genetic frequencies, which of the following must be true?

Accepted Answer

A)  The population statistics must be large. 
B)  Mutations cannot occur. 
C)  Mating must be random. 
D)  All of the above are true. 
A)  The population statistics must be large. 
B)  Mutations cannot occur. 
C)  Mating must be random. 
D)  All of the above are true.

Question 16

Match the term with the definition that best fits.
-Short segment of DNA with a known sequence that can be labeled with a marker

Accepted Answer

A) Restriction fragment-length polymorphism 
B) Polymerase chain reaction 
C) Hybridization 
D) Probe 
E) Amplicon 
A) Restriction fragment-length polymorphism 
B) Polymerase chain reaction 
C) Hybridization 
D) Probe 
E) Amplicon

Question 17

Crossing over occurs during:

Accepted Answer

A)  meiosis. 
B)  mitosis. 
C)  somatic cell division. 
D)  zygote formation. 
A)  meiosis. 
B)  mitosis. 
C)  somatic cell division. 
D)  zygote formation.

Question 18

Match the terms below with the definition that best fits.
-A gene that does not express a detectable product

Accepted Answer

A) Haplotypes 
B) Recessive 
C) Amorphic genes 
D) Codominant genes 
E) Polymorphic 
A) Haplotypes 
B) Recessive 
C) Amorphic genes 
D) Codominant genes 
E) Polymorphic

Question 19

In a family study it was determined that all four siblings in the family had a different blood type: A, B, O, and AB. The parents were most likely ____________.

Accepted Answer

A)  AA and BB 
B)  AO and BB 
C)  OO and AB 
D)  AO and BO 
A)  AA and BB 
B)  AO and BB 
C)  OO and AB 
D)  AO and BO

Question 20

Mitosis results in __________ chromosomes as the original.

Accepted Answer

A)  four cells with half as many 
B)  two cells with the same number of 
C)  four cells with the same number of 
D)  two cells with half as many 
A)  four cells with half as many 
B)  two cells with the same number of 
C)  four cells with the same number of 
D)  two cells with half as many

An advantage of the polymerase chain reaction for viral marker testing is:

If anti-M was reacted with red cells that are M+N+, how would they compare with red cells that are M+N-?

Match the terms below with the definition that best fits. -Having two or more alleles at a given gene locus

Match the term with the definition that best fits. -DNA fragments produced by enzymatic cleavage at specific recognition sites

Match the terms below with the definition that best fits. -When a gene product is expressed only when it is inherited by both parents

If two traits were found to occur higher in a population together than each occurs separately, they may be linked. This would suggest that:

The children of an AB mother and a B father could phenotype as all of the following except:

A person whose red cells type as M+, N+ with antisera would be:

A father carries the Xg^a blood group trait and passes it on to all of his daughters but to none of his sons. What type of inheritance pattern does this demonstrate?

When an individual is said to be group A, it refers to the individual's:

Of the following markers that can be used to test for paternity, which marker provides the most useful statistical value?

Match the term with the definition that best fits. -The binding of two complementary pairs of DNA

Match the terms below with the definition that best fits. -Equal expression of two different inherited genes as in most blood group systems

Match the term with the definition that best fits. -Amplified target sequences of DNA produced by polymerase chain reaction

When using the Hardy-Weinberg equation to calculate genetic frequencies, which of the following must be true?

Match the term with the definition that best fits. -Short segment of DNA with a known sequence that can be labeled with a marker

Crossing over occurs during:

Match the terms below with the definition that best fits. -A gene that does not express a detectable product

In a family study it was determined that all four siblings in the family had a different blood type: A, B, O, and AB. The parents were most likely ____________.

Mitosis results in __________ chromosomes as the original.

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications in Immunohematology

Abo and H Blood Group Systems and Secretor Status

Rh Blood Group System

Other Blood Group Systems

Antibody Detection and Identification

Compatibility Testing

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry

Safety Issues in the Blood Bank

Filters

Exam 3: Genetic Principles in Blood Banking

An advantage of the polymerase chain reaction for viral marker testing is:

If anti-M was reacted with red cells that are M+N+, how would they compare with red cells that are M+N-?

Match the terms below with the definition that best fits. -Having two or more alleles at a given gene locus

Match the term with the definition that best fits. -DNA fragments produced by enzymatic cleavage at specific recognition sites

Match the terms below with the definition that best fits. -When a gene product is expressed only when it is inherited by both parents

If two traits were found to occur higher in a population together than each occurs separately, they may be linked. This would suggest that:

The children of an AB mother and a B father could phenotype as all of the following except:

A person whose red cells type as M+, N+ with antisera would be:

A father carries the Xga blood group trait and passes it on to all of his daughters but to none of his sons. What type of inheritance pattern does this demonstrate?

When an individual is said to be group A, it refers to the individual's:

Of the following markers that can be used to test for paternity, which marker provides the most useful statistical value?

Match the term with the definition that best fits. -The binding of two complementary pairs of DNA

Match the terms below with the definition that best fits. -Equal expression of two different inherited genes as in most blood group systems

Match the term with the definition that best fits. -Amplified target sequences of DNA produced by polymerase chain reaction

When using the Hardy-Weinberg equation to calculate genetic frequencies, which of the following must be true?

Match the term with the definition that best fits. -Short segment of DNA with a known sequence that can be labeled with a marker

Crossing over occurs during:

Match the terms below with the definition that best fits. -A gene that does not express a detectable product

In a family study it was determined that all four siblings in the family had a different blood type: A, B, O, and AB. The parents were most likely ____________.

Mitosis results in __________ chromosomes as the original.

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications in Immunohematology

Abo and H Blood Group Systems and Secretor Status

Rh Blood Group System

Other Blood Group Systems

Antibody Detection and Identification

Compatibility Testing

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry

Safety Issues in the Blood Bank

Filters

A father carries the Xg^a blood group trait and passes it on to all of his daughters but to none of his sons. What type of inheritance pattern does this demonstrate?