Question 1

How long following transfusion must the recipient sample be stored?

Accepted Answer

A)  5 days 
B)  7 days 
C)  10 days 
D)  14 days 
A)  5 days 
B)  7 days 
C)  10 days 
D)  14 days B

Question 2

If the recipient was transfused within the last 3 months, how long from the time of collection can a sample be used for the crossmatch?

Accepted Answer

A)  3 days 
B)  5 days 
C)  7 days 
D)  10 days 
A)  3 days 
B)  5 days 
C)  7 days 
D)  10 days A

Question 3

The immediate spin or abbreviated crossmatch is an acceptable procedure if the recipient:

Accepted Answer

A)  has no prior or existing clinically significant antibodies. 
B)  has never been pregnant or transfused. 
C)  needs blood before a sample can be obtained. 
D)  is using blood from a directed donation. 
A)  has no prior or existing clinically significant antibodies. 
B)  has never been pregnant or transfused. 
C)  needs blood before a sample can be obtained. 
D)  is using blood from a directed donation. A

Question 4

The use of the electronic (computer) crossmatch is restricted to recipients who:

Accepted Answer

A)  are group O. 
B)  do not have a clinically significant antibody. 
C)  have had successful transfusions in the past. 
D)  have transfusion history that has been documented in the computer. 
A)  are group O. 
B)  do not have a clinically significant antibody. 
C)  have had successful transfusions in the past. 
D)  have transfusion history that has been documented in the computer.

Question 5

A recipient phenotypes as group O with the following Rh phenotype: D+C+c-E+e+. If this recipient is transfused with red blood cells from six random group O D-positive donors, what Rh alloantibody could this patient produce as a result of transfusion?

Accepted Answer

A)  Anti-E 
B)  Anti-C 
C)  Anti-c 
D)  Anti-D 
A)  Anti-E 
B)  Anti-C 
C)  Anti-c 
D)  Anti-D

Question 6

An infant less than 4 months old requires which procedures for compatibility testing?

Accepted Answer

A)  Antibody screen with each unit released in a 48-hour period 
B)  ABO and D typing and antibody screen initially only; units released without additional testing if the screen is negative 
C)  Immediate spin crossmatch with each unit released 
D)  Group O, D-negative units; no testing is necessary 
A)  Antibody screen with each unit released in a 48-hour period 
B)  ABO and D typing and antibody screen initially only; units released without additional testing if the screen is negative 
C)  Immediate spin crossmatch with each unit released 
D)  Group O, D-negative units; no testing is necessary

Question 7

Which of the following blood products requires a crossmatch to be performed before issuing?

Accepted Answer

A)  Group AB fresh frozen plasma that is transfused to a group O 
B)  Human leukocyte antigen-matched platelets 
C)  Cryoprecipitated AHF 
D)  Granulocyte concentrates that have more than 2 mL of red blood cells 
A)  Group AB fresh frozen plasma that is transfused to a group O 
B)  Human leukocyte antigen-matched platelets 
C)  Cryoprecipitated AHF 
D)  Granulocyte concentrates that have more than 2 mL of red blood cells

Question 8

Antibodies detected in the immediate spin crossmatch are usually of which of the following immunoglobulin classes?

Accepted Answer

A)  IgA 
B)  IgM 
C)  IgG 
D)  IgD 
A)  IgA 
B)  IgM 
C)  IgG 
D)  IgD

Question 9

An antibody screen on a patient with a prior history of transfusion was negative. The crossmatch, performed at immediate spin and antihuman globulin, was incompatible with 1 unit selected. The next step in the investigation would be to:

Accepted Answer

A)  perform a panel on the patient's serum. 
B)  perform a direct antiglobulin test on the incompatible unit. 
C)  redraw the patient and begin a new crossmatch. 
D)  crossmatch a new unit and discard the incompatible unit. 
A)  perform a panel on the patient's serum. 
B)  perform a direct antiglobulin test on the incompatible unit. 
C)  redraw the patient and begin a new crossmatch. 
D)  crossmatch a new unit and discard the incompatible unit.

Question 10

When group O blood is not available for transfusion, what is the next alternative?

Accepted Answer

A)  Group A red blood cells 
B)  Group AB red blood cells 
C)  Washed group B red blood cells 
D)  None 
A)  Group A red blood cells 
B)  Group AB red blood cells 
C)  Washed group B red blood cells 
D)  None

Question 11

If an emergency exists and there is not enough time to perform a crossmatch for red cells, what is the correct procedure?

Accepted Answer

A)  Release group O, D-negative whole blood. 
B)  Release group O, D-negative red blood cells. 
C)  Release group AB fresh frozen plasma until the blood type is performed. 
D)  Release ABO compatible blood based on the patient's prior record in the computer. 
A)  Release group O, D-negative whole blood. 
B)  Release group O, D-negative red blood cells. 
C)  Release group AB fresh frozen plasma until the blood type is performed. 
D)  Release ABO compatible blood based on the patient's prior record in the computer.

Question 12

In which of the following situations can the crossmatch test be omitted?

Accepted Answer

A)  In a patient who is receiving a directed donation 
B)  In a patient who has received a massive transfusion within a 24-hour period 
C)  In a patient who is pregnant 
D)  In a bone marrow transplant recipient 
A)  In a patient who is receiving a directed donation 
B)  In a patient who has received a massive transfusion within a 24-hour period 
C)  In a patient who is pregnant 
D)  In a bone marrow transplant recipient

Question 13

What are the two components of the major crossmatch?

Accepted Answer

A)  Recipient red cells and donor serum 
B)  Donor red cells and recipient serum 
C)  Reverse ABO cells and recipient serum 
D)  Screening cells and donor serum 
A)  Recipient red cells and donor serum 
B)  Donor red cells and recipient serum 
C)  Reverse ABO cells and recipient serum 
D)  Screening cells and donor serum

Question 14

For autologous units transfused within the collection facility, which part of the compatibility procedure is not required?

Accepted Answer

A)  ABO phenotyping 
B)  D phenotyping 
C)  Antibody screen 
D)  Transfusion history check 
A)  ABO phenotyping 
B)  D phenotyping 
C)  Antibody screen 
D)  Transfusion history check

Question 15

Which of the following tests is not included in routine compatibility testing?

Accepted Answer

A)  ABO phenotyping 
B)  Direct antiglobulin test 
C)  D typing 
D)  Antibody screen 
A)  ABO phenotyping 
B)  Direct antiglobulin test 
C)  D typing 
D)  Antibody screen

Question 16

Patient M.M. was admitted to the hospital with acute bleeding. Anti-E was detected in the patient's serum. Four E-negative units of blood were crossmatched for the patient. The units were compatible at immediate spin and following the antiglobulin test. After the antiglobulin test was performed, IgG sensitized red cells gave a 2+ agglutination reaction. The proper interpretation of this 2+ agglutination reaction is the:

Accepted Answer

A)  antihuman globulin washing procedure was adequate. 
B)  IgG-sensitized red cells spontaneously agglutinated. 
C)  crossmatch was incompatible. 
D)  patient's anti-E reacted with the IgG-sensitized red cells. 
A)  antihuman globulin washing procedure was adequate. 
B)  IgG-sensitized red cells spontaneously agglutinated. 
C)  crossmatch was incompatible. 
D)  patient's anti-E reacted with the IgG-sensitized red cells.

Question 17

To what does the abbreviation "MSBOS" refer?

Accepted Answer

A)  Monthly surgical blood order schedule 
B)  Minimum surgical blood order staffing 
C)  Maximum blood order schedule 
D)  Minimum safe blood order schedule 
A)  Monthly surgical blood order schedule 
B)  Minimum surgical blood order staffing 
C)  Maximum blood order schedule 
D)  Minimum safe blood order schedule

Question 18

All of the following may be used to perform an antibody screen for an infant less than 4 months old except:

Accepted Answer

A)  infant serum. 
B)  paternal serum. 
C)  maternal serum. 
D)  infant eluate. 
A)  infant serum. 
B)  paternal serum. 
C)  maternal serum. 
D)  infant eluate.

Question 19

Your blood bank mistakenly transfused 1 unit of D-positive red blood cells to a patient who was typed as D-negative. The patient had no history of a previous transfusion or pregnancy. Antibody detection testing was negative in pretransfusion testing. The crossmatch in this case was:

Accepted Answer

A)  compatible at immediate spin. 
B)  incompatible at immediate spin only. 
C)  not necessary to perform. 
D)  incompatible at antihuman globulin only. 
A)  compatible at immediate spin. 
B)  incompatible at immediate spin only. 
C)  not necessary to perform. 
D)  incompatible at antihuman globulin only.

Question 20

Given the following red cell antigen frequencies:  
Which of the following red cell alloantibodies would be responsible for incompatible crossmatches with one 1 of 10 random donor units?

Accepted Answer

A)  Anti-K 
B)  Anti-E 
C)  Anti-k 
D)  Anti-P1 
A)  Anti-K 
B)  Anti-E 
C)  Anti-k 
D)  Anti-P1

How long following transfusion must the recipient sample be stored?

If the recipient was transfused within the last 3 months, how long from the time of collection can a sample be used for the crossmatch?

The immediate spin or abbreviated crossmatch is an acceptable procedure if the recipient:

The use of the electronic (computer) crossmatch is restricted to recipients who:

A recipient phenotypes as group O with the following Rh phenotype: D+C+c-E+e+. If this recipient is transfused with red blood cells from six random group O D-positive donors, what Rh alloantibody could this patient produce as a result of transfusion?

An infant less than 4 months old requires which procedures for compatibility testing?

Which of the following blood products requires a crossmatch to be performed before issuing?

Antibodies detected in the immediate spin crossmatch are usually of which of the following immunoglobulin classes?

An antibody screen on a patient with a prior history of transfusion was negative. The crossmatch, performed at immediate spin and antihuman globulin, was incompatible with 1 unit selected. The next step in the investigation would be to:

When group O blood is not available for transfusion, what is the next alternative?

If an emergency exists and there is not enough time to perform a crossmatch for red cells, what is the correct procedure?

In which of the following situations can the crossmatch test be omitted?

What are the two components of the major crossmatch?

For autologous units transfused within the collection facility, which part of the compatibility procedure is not required?

Which of the following tests is not included in routine compatibility testing?

To what does the abbreviation "MSBOS" refer?

All of the following may be used to perform an antibody screen for an infant less than 4 months old except:

Your blood bank mistakenly transfused 1 unit of D-positive red blood cells to a patient who was typed as D-negative. The patient had no history of a previous transfusion or pregnancy. Antibody detection testing was negative in pretransfusion testing. The crossmatch in this case was:

Given the following red cell antigen frequencies: Which of the following red cell alloantibodies would be responsible for incompatible crossmatches with one 1 of 10 random donor units?

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications in Immunohematology

Genetic Principles in Blood Banking

Abo and H Blood Group Systems and Secretor Status

Rh Blood Group System

Other Blood Group Systems

Antibody Detection and Identification

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry

Safety Issues in the Blood Bank

Filters

Exam 8: Compatibility Testing

How long following transfusion must the recipient sample be stored?

If the recipient was transfused within the last 3 months, how long from the time of collection can a sample be used for the crossmatch?

The immediate spin or abbreviated crossmatch is an acceptable procedure if the recipient:

The use of the electronic (computer) crossmatch is restricted to recipients who:

A recipient phenotypes as group O with the following Rh phenotype: D+C+c-E+e+. If this recipient is transfused with red blood cells from six random group O D-positive donors, what Rh alloantibody could this patient produce as a result of transfusion?

An infant less than 4 months old requires which procedures for compatibility testing?

Which of the following blood products requires a crossmatch to be performed before issuing?

Antibodies detected in the immediate spin crossmatch are usually of which of the following immunoglobulin classes?

An antibody screen on a patient with a prior history of transfusion was negative. The crossmatch, performed at immediate spin and antihuman globulin, was incompatible with 1 unit selected. The next step in the investigation would be to:

When group O blood is not available for transfusion, what is the next alternative?

If an emergency exists and there is not enough time to perform a crossmatch for red cells, what is the correct procedure?

In which of the following situations can the crossmatch test be omitted?

What are the two components of the major crossmatch?

For autologous units transfused within the collection facility, which part of the compatibility procedure is not required?

Which of the following tests is not included in routine compatibility testing?

To what does the abbreviation "MSBOS" refer?

All of the following may be used to perform an antibody screen for an infant less than 4 months old except:

Your blood bank mistakenly transfused 1 unit of D-positive red blood cells to a patient who was typed as D-negative. The patient had no history of a previous transfusion or pregnancy. Antibody detection testing was negative in pretransfusion testing. The crossmatch in this case was:

Given the following red cell antigen frequencies: Which of the following red cell alloantibodies would be responsible for incompatible crossmatches with one 1 of 10 random donor units?

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications in Immunohematology

Genetic Principles in Blood Banking

Abo and H Blood Group Systems and Secretor Status

Rh Blood Group System

Other Blood Group Systems

Antibody Detection and Identification

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry

Safety Issues in the Blood Bank

Filters