Exam 18: Genomics: Genetics From a Whole-Genome Perspective

Subtelomeres are blocks of homologous DNA sequences close to the ends of chromosomes.In a worldwide population of humans,when sequences of chromosomes 4q and 10q subtelomeres were analyzed only 17 4q and 8 10q haplotypes were found among African,European,and Asian groups.Which of the following might be among the results or conclusions of this analysis?

In humans,a large number of genes associated with immune function share sequence similarity and are evolutionarily related.These would be known as what kind of group?

Being able to do a BLAST search,among other things,assumes that you and every other researcher has access to known gene sequences.Some would prefer,however,that such sequence information should be "owned" by their discoverers.What are the pros and cons of such a position?

Sequencing of DNA from a community of organisms rather than from a single individual is known as ________.

In an experiment designed to analyze the mRNAs present in a cell at a given time in the life cycle,it was found that about 50% of the mRNAs are of one type,less than 20% represent 8 other mRNAs,and the rest consist of several thousand different mRNAs.What does this information indicate?

When authors discuss whole genome-wide examination of genes,to what do they refer?

The process of finding the location of genes and functional (e.g.,regulatory)sequences and their functions within a genome sequence is called ________.

The BLAST program from NIH enables a researcher to look for homologous genes.It does so in general by searching for identity in what property?

Suppose that you use the sequence of the lacI gene,whose function you know is to encode a transcription factor,to find similar sequences in another bacterial strain.Are you more likely to find similar operons or similar transcription factors?

Which of the following defines the essential gene set of an organism such as a species of yeast?