Exam 5: Inferring Phylogeny
Exam 1: An Overview of Evolutionary Biology40 Questions
Exam 2: Early Evolutionary Ideas and Darwins Insight43 Questions
Exam 3: Natural Selection45 Questions
Exam 4: Phylogeny and Evolutionary History43 Questions
Exam 5: Inferring Phylogeny47 Questions
Exam 6: Transmission Genetics and the Sources of Genetic Variation43 Questions
Exam 7: The Genetics of Populations42 Questions
Exam 8: Evolution in Finite Populations38 Questions
Exam 9: Evolution at Multiple Loci39 Questions
Exam 10: Genome Evolution38 Questions
Exam 11: The Origin and Evolution of Early Life42 Questions
Exam 12: Major Transitions42 Questions
Exam 13: Evolution and Development39 Questions
Exam 14: Species and Speciation37 Questions
Exam 15: Extinction and Evolutionary Trends25 Questions
Exam 16: The Evolution of Sex32 Questions
Exam 17: Sexual Selection23 Questions
Exam 18: The Evolution of Sociality31 Questions
Exam 19: Coevolution26 Questions
Exam 20: Evolution and Medicine27 Questions
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Why is phylogenetic inference a difficult and computationally intensive problem? What solution do evolutionary biologists use to address this problem?
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If two nonsister species on the phylogenetic tree in the figure above differ from the other two in a single character state (e.g.,dark or light fur),where would the likely evolutionary change(s)be? Indicate change(s)by drawing an X-or Xs-on the tree above.Be sure to label each X as a loss or gain.

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The maximum likelihood tree constructed for the mammals in the figures above supports which of the competing hypotheses for the evolutionary relationships among mammalian groups?

(Multiple Choice)
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How many unrooted trees are possible for a 22-species tree?
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On the figure above,number each of the seven change bars on the branches with the corresponding sequence change indicated on the sequence alignment.

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An unrooted tree,linking three species,is shown above.Draw all possible unrooted tree conformations when a fourth species,D,is added to the tree.

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Why do some evolutionary biologists have philosophical concerns about using distance methods to construct evolutionary trees?
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The disadvantages of using distance methods to construct trees include the fact that
(Multiple Choice)
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Arrange the steps of constructing a phylogenetic tree using the distance method in the correct order.
1)A distance matrix is created.
2)Trees are constructed by arranging segments or branches derived from pair-wise distance comparisons.
3)The distance between species is measured using character state changes.
4)Phylogenetic inference software is used to choose the best tree.
(Multiple Choice)
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The advantages of using distance methods to construct trees include the fact that
(Multiple Choice)
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If two sister species on the phylogenetic tree in the figure above differ from the other two in a single character state (e.g.,dark or light fur),where would the likely evolutionary change(s)be? Indicate change(s)by placing an arrow-or arrows-on the tree above.Be sure to label the arrow(s)as a loss or gain.

(Essay)
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In the spring of 1999,six medics were accused of purposely infecting over 400 Libyan children with HIV in a Benghazi hospital.Explain how a team of researchers were able to construct and use the phylogeny in the figure above to convince the Libyan Court to lift its death sentence for the "Bulgarian six."

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Arrange the following steps of bootstrap resampling in the correct order.
1)To assess the support for any feature of the original tree,the percentage of replicate trees that also display that feature are calculated.
2)Resampling is done from the original character matrix to create a collection of bootstrap replicate data sets.
3)A tree is constructed for the estimated phylogeny,based on the original character matrix.
4)The same tree-building methods used on the original character set are used to create a collection of bootstrap replicate phylogenies.
(Multiple Choice)
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While both parsimony methods and distance methods can be quite effective in inferring evolutionary history,both use tricks of sorts.Compare the assumptions,shortcomings,and methods of each.
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Phylogenetic methods developed by evolutionary biologists to find the best tree possible for the taxa being studied include
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The role of organisms in impacting the external environment
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