Exam 20: Genetic Testing and Treatment

A retrovirus is given a functional version of a gene that a patient lacks and used to infect the patient's skin cells growing in culture.Skin is grown from the altered cells and grafted onto the patient.If all works well,the graft will

The liver is a good candidate for gene therapy because

Newborn screening using tandem mass spectrometry identifies certain single-gene disorders by detecting

The defect in Canavan disease that causes the symptoms is

The field of genetic counseling began when the term was coined

Gene therapy to treat muscular dystrophy targets the gene that encodes

A genetic counselor might discuss assisted reproductive technologies with a couple who wish to

Maxwell needs to take an anti-depressant drug.He enrolls in a clinical trial to detect genetic variants and gene expression profiles associated with response to various drugs.This approach to selecting a therapeutic drug is called

Reginald receives a stem cell transplant to treat a blood cancer,multiple myeloma.His treatment is an example of

Rita has been diagnosed with Her2 breast cancer,and is prescribed Herceptin.The approach of basing a drug prescribing decision on the results of a single-gene test is called

Which is an example of a germline gene therapy?

Muscle is a good target for gene therapy because

Adenosine deaminase (ADA)deficiency results in

Which of the following might a genetic counselor do as part of her job?

A nasal spray for cystic fibrosis patients,which contains adenovirus particles carrying a normal human CFTR gene,is an example of

One of the first applications of pharmacogenetics in prescribing drugs is for

Nondirective genetic counseling

Using gene therapy to correct ornithine transcarbamylase deficiency (OTC)would prevent buildup of _________ in the blood.

The phrase "When you hear hoofbeats,think horses,not zebras" applies to genetics in that

Many children born with ornithine transcarbamylase deficiency (OTC)die within seventy-two hours of birth.Jesse Gelsinger was not diagnosed with OTC until he was two because _______ and therefore his symptoms were milder.