Question 1

Give the product for the following reaction.

Accepted Answer

A)    
B)    
C)    
D)    
E)    
A)    
B)    
C)    
D)    
E)

Question 2

Which of the following vitamins is the only lipid-soluble vitamin that is known to function as a coenzyme?

Accepted Answer

A) vitamin A 
B) vitamin D 
C) vitamin B1 
D) vitamin C 
E) vitamin K 
A) vitamin A 
B) vitamin D 
C) vitamin B1 
D) vitamin C 
E) vitamin K

Question 3

Give the purpose of TPP as a coenzyme.

Accepted Answer

A) a coenzyme that catalyzes the transfer of a one-carbon fragment 
B) a coenzyme that catalyzes the carboxylation of the alpha carbon 
C) a coenzyme that catalyzes the transfer of a three-carbon fragment 
D) a coenzyme that catalyzes the carboxylation of the beta carbon 
E) a coenzyme that catalyzes the transfer of a two-carbon fragment 
A) a coenzyme that catalyzes the transfer of a one-carbon fragment 
B) a coenzyme that catalyzes the carboxylation of the alpha carbon 
C) a coenzyme that catalyzes the transfer of a three-carbon fragment 
D) a coenzyme that catalyzes the carboxylation of the beta carbon 
E) a coenzyme that catalyzes the transfer of a two-carbon fragment

Question 4

Which of the following is/are coenzyme(s)formed from the vitamin niacin?

Accepted Answer

A) NAD+ 
B) NADP+ 
C) NADH 
D) NADPH 
E) all of the above 
A) NAD+ 
B) NADP+ 
C) NADH 
D) NADPH 
E) all of the above

Question 5

Propose a mechanism for the vitamin KH2-catalyzed carboxylation of glutamate shown below.

Accepted Answer

Question 6

In addition to TPP,which of the following coenzymes is/are required to facilitate the following reaction?

Accepted Answer

A) lipoate 
B) coenzyme A 
C) FAD 
D) NAD+ 
E) all of the above 
A) lipoate 
B) coenzyme A 
C) FAD 
D) NAD+ 
E) all of the above

Question 7

A quinone is part of the structure of vitamin

Accepted Answer

A) B12. 
B) B1. 
C) B2. 
D) 
C)  
E) K) 
A) B12. 
B) B1. 
C) B2. 
D) 
C)  
E) K)

Question 8

A metal ion cofactor act as a ________ in enzyme catalyzed reactions

Accepted Answer

A) Lewis base 
B) Lewis acid 
C) Bronsted acid 
D) Bronsted base 
E) none of the above 
A) Lewis base 
B) Lewis acid 
C) Bronsted acid 
D) Bronsted base 
E) none of the above

Question 9

Propose a mechanism for the following reaction.

Accepted Answer

The answer of Propose a mechanism for the following reaction....

Question 10

Which of the following reactions is called an α,β-elimination of an amino acid?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 11

Can an NAD+/NADH dependent enzyme tell the difference between the pro-R hydrogen and pro-S hydrogen of a substrate? Explain.

Accepted Answer

The enzyme can tell the difference betwe

Question 12

The thiazolium ring of ________ acts as electron sink when it participates in metabolic reactions.

Accepted Answer

A) TTP 
B) CoASH 
C) PLP 
D) THF 
E) FAD 
A) TTP 
B) CoASH 
C) PLP 
D) THF 
E) FAD

Question 13

Which of the following are required species for biotin-dependent enzymes?

Accepted Answer

A) ATP 
B) Mg+2 
C) HCO3- 
D) A and B 
E) A,B,and C 
A) ATP 
B) Mg+2 
C) HCO3- 
D) A and B 
E) A,B,and C

Question 14

Identify the first step in the mechanism for the vitamin KH2-dependent carboxylation of glutamate.

Accepted Answer

A) The vitamin K base removes a proton from the gamma-carbon of the gluatamate. 
B) The vitamin loses a proton from a phenolic OH group. 
C) The dioxetane collapses to form a vitamin K base. 
D) The base attacks molecular oxygen. 
E) The glutamate carbanion attacks carbon dioxide. 
A) The vitamin K base removes a proton from the gamma-carbon of the gluatamate. 
B) The vitamin loses a proton from a phenolic OH group. 
C) The dioxetane collapses to form a vitamin K base. 
D) The base attacks molecular oxygen. 
E) The glutamate carbanion attacks carbon dioxide.

Question 15

Which molecule does the following structure represent?

Accepted Answer

A) FAD 
B) FADH2 
C) NAD+ 
D) NADP+ 
E) ATP 
A) FAD 
B) FADH2 
C) NAD+ 
D) NADP+ 
E) ATP

Question 16

Through what enzymatic pathway is thymine biosynthesized?

Accepted Answer

The Ts used for the biosynthesis of DNA

Question 17

Show the transimination (trans-Schiffization)reaction that happens in all PLP-requiring enzymes in which the amino acid substrate forms a Schiff base with PLP,thereby freeing the lysine side chain.

Accepted Answer

The answer of Show the transimination (trans-Schiffization)reaction that happens in...

Question 18

Identify the true statement(s).You may choose more than one answer.

Accepted Answer

A) FAD is an oxidizing agent. 
B) FADH2 is an oxidizing agent. 
C) FMNH2 is a reducing agent. 
D) NADH is an oxidizing agent. 
E) NADPH is a reducing agent. 
A) FAD is an oxidizing agent. 
B) FADH2 is an oxidizing agent. 
C) FMNH2 is a reducing agent. 
D) NADH is an oxidizing agent. 
E) NADPH is a reducing agent.

Question 19

Which of the following vitamins catalyzes acyl transfer reactions and requires CoASH as a coenzyme?

Accepted Answer

A) niacin 
B) thiamine 
C) vitamin B12 
D) lipoate 
E) panthothenate 
A) niacin 
B) thiamine 
C) vitamin B12 
D) lipoate 
E) panthothenate

Question 20

What are catabolic and anabolic reactions?

Accepted Answer

Catabolic reactions are reactions where

Exam 23: The Organic Chemistry of the Coenzymes, compounds Derived From Vitamins

Give the product for the following reaction.

Which of the following vitamins is the only lipid-soluble vitamin that is known to function as a coenzyme?

Give the purpose of TPP as a coenzyme.

Which of the following is/are coenzyme(s)formed from the vitamin niacin?

Propose a mechanism for the vitamin KH2-catalyzed carboxylation of glutamate shown below.

In addition to TPP,which of the following coenzymes is/are required to facilitate the following reaction?

A quinone is part of the structure of vitamin

A metal ion cofactor act as a ________ in enzyme catalyzed reactions

Propose a mechanism for the following reaction.

Which of the following reactions is called an α,β-elimination of an amino acid?

Can an NAD+/NADH dependent enzyme tell the difference between the pro-R hydrogen and pro-S hydrogen of a substrate? Explain.

The thiazolium ring of ________ acts as electron sink when it participates in metabolic reactions.

Which of the following are required species for biotin-dependent enzymes?

Identify the first step in the mechanism for the vitamin KH2-dependent carboxylation of glutamate.

Which molecule does the following structure represent?

Through what enzymatic pathway is thymine biosynthesized?

Show the transimination (trans-Schiffization)reaction that happens in all PLP-requiring enzymes in which the amino acid substrate forms a Schiff base with PLP,thereby freeing the lysine side chain.

Identify the true statement(s).You may choose more than one answer.

Which of the following vitamins catalyzes acyl transfer reactions and requires CoASH as a coenzyme?

What are catabolic and anabolic reactions?

Remembering General Chemistry: Electronic Structure and Bonding

Acids and Bases: Central to Understanding Organic Chemistry

An Introduction to Organic Compounds: Nomenclature, physical Properties, and Structure

Isomers: the Arrangement of Atoms in Space

Alkenes: Structure,nomenclature,and an Introduction to Reactivity - Thermodynamics and Kinetics

The Reactions of Alkenes - the Stereochemistry of Addition Reactions

The Reactions of Alkynes - Introduction to Multistep Synthesis

Delocalized Electrons: Their Effect on Stability, pka, and the Products of a Reaction - Aromaticity and Electronic Effects: an Introduction to the Reactions of Benzene

Substitution and Elimination Reactions of Alkyl Halides

Reactions of Alcohols, ethers, epoxides, amines and Sulfur-Containing Compounds

Organometallic Compounds

Radicals

Mass Spectrometry,infrared Spectroscopy,and Uvvis Spectroscopy

Nmr Spectroscopy

Reactions of Carboxylic Acids and Carboxylic Acid Derivatives

Reactions of Aldehydes and Ketones

Reactions at the Α-Carbon

Reactions of Benzene and Substituted Benzenes

More About Amines - Reactions of Heterocylic Compounds

The Organic Chemistry of Carbohydrates

Amino Acids,peptides,and Proteins

Catalysis in Organic Reactions and in Enzymatic Reactions

The Organic Chemistry of the Metabolic Pathways

The Organic Chemistry of Lipids

The Chemistry of the Nucleic Acids

Synthetic Polymers

Pericyclic Reactions

Filters

Propose a mechanism for the vitamin KH₂-catalyzed carboxylation of glutamate shown below.

Can an NAD⁺/NADH dependent enzyme tell the difference between the pro-R hydrogen and pro-S hydrogen of a substrate? Explain.

Identify the first step in the mechanism for the vitamin KH₂-dependent carboxylation of glutamate.