Question 1

All of the following are considered acute phase reactants EXCEPT:

Accepted Answer

A)  fibrinogen 
B)  complement 
C)  C-reactive protein 
D)  TNF-alpha 
A)  fibrinogen 
B)  complement 
C)  C-reactive protein 
D)  TNF-alpha

Question 2

The function(s)of macrophages/monocytes in the host immune response is (are):

Accepted Answer

A)  antigen presentation 
B)  phagocytosis 
C)  secretion of cytokines 
D)  all of these 
A)  antigen presentation 
B)  phagocytosis 
C)  secretion of cytokines 
D)  all of these

Question 3

Which of the following is part of the external defense system?

Accepted Answer

A)  ceruloplasmin 
B)  skin 
C)  neutrophils 
D)  complement 
A)  ceruloplasmin 
B)  skin 
C)  neutrophils 
D)  complement

Question 4

Diapedesis is:

Accepted Answer

A)  movement of cells in response to increasing concentration of a cytokine 
B)  attachment of immunoglobulin to target cells 
C)  cells squeezing through endothelial cells to leave the circulation 
D)  engulfment of target cells 
A)  movement of cells in response to increasing concentration of a cytokine 
B)  attachment of immunoglobulin to target cells 
C)  cells squeezing through endothelial cells to leave the circulation 
D)  engulfment of target cells

Question 5

What is the major function of C-reactive protein (CRP)?

Accepted Answer

A)  acts as an opsonin 
B)  binds hemoglobin 
C)  causes vasodilation 
D)  helps to form clots 
A)  acts as an opsonin 
B)  binds hemoglobin 
C)  causes vasodilation 
D)  helps to form clots

Question 6

Measurement of CRP levels could be used for which of the following?

Accepted Answer

A)  to determine risk of a heart attack 
B)  to determine flare-up of rheumatoid arthritis 
C)  to detect an inflammatory process 
D)  all of the above 
A)  to determine risk of a heart attack 
B)  to determine flare-up of rheumatoid arthritis 
C)  to detect an inflammatory process 
D)  all of the above

Question 7

Acquired immunity can be characterized by which of the following?

Accepted Answer

A)  nonspecific 
B)  immediate response 
C)  depends on neutrophils and macrophages 
D)  involves memory 
A)  nonspecific 
B)  immediate response 
C)  depends on neutrophils and macrophages 
D)  involves memory

Question 8

Which of the following acute phase reactants is an important clotting factor?

Accepted Answer

A)  haptoglobin 
B)  ceruloplasmin 
C)  fibrinogen 
D)  alpha-2 macroglobulin 
A)  haptoglobin 
B)  ceruloplasmin 
C)  fibrinogen 
D)  alpha-2 macroglobulin

Question 9

Which white cell in the peripheral blood migrates to the tissue to become a macrophage?

Accepted Answer

A)  eosinophil 
B)  basophil 
C)  neutrophil 
D)  monocyte 
A)  eosinophil 
B)  basophil 
C)  neutrophil 
D)  monocyte

Question 10

Which of the following is true of NK cells?

Accepted Answer

A)  They produce antibody. 
B)  They are capable of phagocytosis. 
C)  They have markers CD4 and CD16. 
D)  They kill tumor and virally infected cells. 
A)  They produce antibody. 
B)  They are capable of phagocytosis. 
C)  They have markers CD4 and CD16. 
D)  They kill tumor and virally infected cells.

Question 11

Macrophages recognize target cells using which of the following?

Accepted Answer

A)  MHC class II 
B)  mannose receptors 
C)  T-cell receptor 
D)  killer cell inhibitory receptors 
A)  MHC class II 
B)  mannose receptors 
C)  T-cell receptor 
D)  killer cell inhibitory receptors

Question 12

Which of the following can be measured as an indicator of inflammation?

Accepted Answer

A)  temperature 
B)  number of WBCs 
C)  erythrocyte sedimentation rate 
D)  two of these 
E)  all of these 
A)  temperature 
B)  number of WBCs 
C)  erythrocyte sedimentation rate 
D)  two of these 
E)  all of these

Question 13

All of the following are examples of natural immunity EXCEPT:

Accepted Answer

A)  skin as a structural barrier 
B)  acute phase reactants 
C)  phagocytosis 
D)  antibodies 
A)  skin as a structural barrier 
B)  acute phase reactants 
C)  phagocytosis 
D)  antibodies

Question 14

All of the following occur during the process of inflammation EXCEPT:

Accepted Answer

A)  increased capillary permeability 
B)  migration of basophils to tissue 
C)  increase in blood flow 
D)  swelling and pain 
A)  increased capillary permeability 
B)  migration of basophils to tissue 
C)  increase in blood flow 
D)  swelling and pain

Question 15

The function(s)of macrophages/monocytes in the host immune response is (are):

Accepted Answer

A)  antigen presentation 
B)  phagocytosis 
C)  secretion of cytokines 
D)  all of these 
A)  antigen presentation 
B)  phagocytosis 
C)  secretion of cytokines 
D)  all of these

Question 16

What is the name of the process by which phagocytic cells are attracted toward a substance such as complement fragment C3a?

Accepted Answer

A)  diapedesis 
B)  degranulation 
C)  chemotaxis 
D)  opsonization 
A)  diapedesis 
B)  degranulation 
C)  chemotaxis 
D)  opsonization

Question 17

Which of the following represents the best explanation for the action of natural killer (NK)cells?

Accepted Answer

A)  They recognize specific antigen. 
B)  They kill if MHC class I is present. 
C)  They kill by releasing perforins. 
D)  They participate in phagocytosis. 
A)  They recognize specific antigen. 
B)  They kill if MHC class I is present. 
C)  They kill by releasing perforins. 
D)  They participate in phagocytosis.

Question 18

Acquired (adaptive)immunity can be characterized by which of the following?

Accepted Answer

A)  nonspecific 
B)  immediate response 
C)  depends on neutrophils and macrophages 
D)  involves memory 
A)  nonspecific 
B)  immediate response 
C)  depends on neutrophils and macrophages 
D)  involves memory

Question 19

Which of the following are directly used in oxidative killing of target cells?

Accepted Answer

A)  hydrogen peroxide 
B)  lysozyme 
C)  defensin 
D)  TNF-alpha 
A)  hydrogen peroxide 
B)  lysozyme 
C)  defensin 
D)  TNF-alpha

Question 20

Which of the following best explains the reaction that takes place in the latex agglutination slide test for CRP?

Accepted Answer

A)  Latex particles are coated with anti-CRP. 
B)  Latex particles are coated with CRP. 
C)  Latex particles are nonspecifically bound. 
D)  CRP is acting as an antibody. 
A)  Latex particles are coated with anti-CRP. 
B)  Latex particles are coated with CRP. 
C)  Latex particles are nonspecifically bound. 
D)  CRP is acting as an antibody.

Exam 1: Introduction and Natural Immunity

All of the following are considered acute phase reactants EXCEPT:

The function(s)of macrophages/monocytes in the host immune response is (are):

Which of the following is part of the external defense system?

Diapedesis is:

What is the major function of C-reactive protein (CRP)?

Measurement of CRP levels could be used for which of the following?

Acquired immunity can be characterized by which of the following?

Which of the following acute phase reactants is an important clotting factor?

Which white cell in the peripheral blood migrates to the tissue to become a macrophage?

Which of the following is true of NK cells?

Macrophages recognize target cells using which of the following?

Which of the following can be measured as an indicator of inflammation?

All of the following are examples of natural immunity EXCEPT:

All of the following occur during the process of inflammation EXCEPT:

The function(s)of macrophages/monocytes in the host immune response is (are):

What is the name of the process by which phagocytic cells are attracted toward a substance such as complement fragment C3a?

Which of the following represents the best explanation for the action of natural killer (NK)cells?

Acquired (adaptive)immunity can be characterized by which of the following?

Which of the following are directly used in oxidative killing of target cells?

Which of the following best explains the reaction that takes place in the latex agglutination slide test for CRP?

Lymphoid System

Nature of Antigens and Major Histocompatibility Complex

Antibody Structure and Function

Cytokines

Complement System

Safety and Specimen Preparation

Precipitation Reactions

Agglutination

Labeled Immunoassays

Molecular Techniques

Flow Cytometry and Laboratory Automation

Hypersensitivity

Autoimmunity

Immunoproliferative Diseases

Immunodeficiency Disease

Transplantation Immunology

Tumor Immunology

Serologic and Molecular Detection of Bacterial Infections

Serologic and Molecular Detection of Bacterial Infections

Serology of Parasitic and Fungal Infections

Spirochete Diseases

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