Exam 7: Interactions Between Cells and Their Environment

________ are members of an integral membrane glycoprotein family that bind to specific sugar arrangements in oligosaccharides that project from the surfaces of other cells.

Mesenchymal stem cells were grown on a soft,pliable substratum.Into what type of cells did they develop?

What kind of experiments have provided evidence that most integrins have unique functions?

Mesenchymal stem cells were grown on a very stiff substrate.Into what type of cells did they develop?

Mesenchymal stem cells were grown on a substratum of moderate stiffness.Into what type of cells did they develop?

What integral membrane protein family made of two membrane-spanning chains ( $\alpha$ and $\beta$ )is involved in attaching cells to their extracellular microenvironment?

If antibodies to fibronectin are exposed to an embryo through which neural crest cells are migrating,what happens?

From what cell organelle does the desmotubule appear to be derived?

The loss of cadherin function may be instrumental in what disease state?

The cells of the epiblast of a developing mammalian embryo display what cell adhesion molecules on their surfaces,molecules that presumably promote their close association with one another?

Which of the following tissues are typically derived from mesenchymal cells?

What is the function of most IgSFs?

You study another tissue that also contains a fibrillar component.In this tissue,however,the fibers are arranged in layers with each layer perpendicular to those above and below it.In addition,the fibers are uniform in size.What properties would such a tissue have?

Which tissues below are not typically derived from the cells on the dorsal surface of a mammalian embryo after gastrulation that express N-cadherins and stop expressing E-cadherins?

What could be defined as an organized network of extracellular materials found beyond the immediate vicinity of the plasma membrane?

The filaments associated with hemidesmosomes are __________.

L1 is an IgSF molecule that has been shown to be important in neural development;it is thought that it may be involved in axon growth within the embryonic nervous system.What evidence supports this statement?

What kind of molecule does not pass through a gap junction?

To what is the cytoplasmic domain of integrins in the region of a focal contact connected via various adaptors?

Despite the presence of the blood-brain barrier,what cells,oddly enough,can pass through the blood-brain barrier by sending a signal that opens up the junction?