Exam 22: Population Genetics and Evolution

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Given the following pedigree, what is the coefficient of inbreeding for individual IV-1? Given the following pedigree, what is the coefficient of inbreeding for individual IV-1?

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C

The coefficient of inbreeding (F)can be used to estimate the proportion of loci that are __________.

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________ is an evolutionary mechanism that favors the reproductive success of certain members of a population over others as a result of differences in anatomical, physiological, or behavioral traits they possess.

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Natural selection

Both the founder effect and the bottleneck effect are mechanisms that produce large allele frequency sampling errors in a small population due to __________.

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Which aspect of population genetics refers to chance fluctuations of allele frequencies resulting from sampling error and is more prominent in small, isolated populations?

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In the general population, 1 in 300 individuals is a carrier for Tay-Sachs disease, while 1 in 30 individuals of Ashkenazi Jew descent are carriers. Tay-Sachs also affects 1 in 30 individuals with French-Canadian ancestry, although two completely unique mutations are responsible for the Ashkenazi and French-Canadian mutations. What are the chances of two individuals who are carriers having a child with Tay-Sachs if a. both individuals are not of Ashkenazi or French-Canadian descent? b. one individual is of Ashkenazi descent and one is not? c. both individuals are of Ashkenazi descent?

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Which of the following is an example of a postzygotic mechanism for reproductive isolation?

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Of the five aspects of Hardy-Weinberg equilibrium, which one directly affects phenotypic frequencies for both rather than genotypic frequencies?

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In CODIS, what type of genetic marker is used to predict population genotype frequencies?

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The pattern of species evolution known as ________ is one of branching in which an ancestral species gives rise to two or more new species.

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In a group of 500 people, the frequency of genotype NN is 40%. Assuming both autosomal inheritance and that the population is in Hardy-Weinberg equilibrium, how many individuals would you expect to have the MN genotype?

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Forward and reverse mutation can create a ________, given a sufficient number of generations and the absence of other evolutionary processes.

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In the same population of patients you examined for sickle cell allele frequencies, you now want to test whether the disease symptoms are related to blood type. Since blood type is a codominant trait and the alleles are easily identifiable by the phenotype (blood type)of the individuals, which method is most helpful for identifying blood type allele frequency?

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If an X-linked recessive trait has a frequency of 5% in males, what percentage of females are carriers? (Assume that the population is in Hardy-Weinberg equilibrium.)

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If the relative fitness value is w = 0.6, what is the selection coefficient used to identify the differences between the fitnesses of organisms with different traits?

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Mexican hairless dogs are heterozygous (Hh), carrying a single copy of the recessive lethal allele. In a given population, the Hh genotypic frequency is 60% and the frequency of each homozygote Is 20%. Assuming w = 1 for the Hh and hh dogs, what is the estimated genotypic frequency of the lethal HH genotype after reproduction?

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Using the allele frequencies in the table below, what is the probability that a random person would be heterozygous 12/14 for VAW? Using the allele frequencies in the table below, what is the probability that a random person would be heterozygous 12/14 for VAW?

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When populations share a single habitat but are isolated by genetic or postzygotic mechanisms that prevent gene flow, what process can cause populations to diverge?

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The process by which an original species is transformed into a new species over an extended period of time that spans many generations is known as __________.

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In a theoretical population where f (A1)= 0.95 and f (A2)= 0.05, µ = 1 × 10-6, and v = 1 × 10-7, what is Δq?

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