Question 1

Which drug is both an alpha- and beta-adrenoceptor-blocking agent?

Accepted Answer

A) prazosin (Minipress) 
B) tamsulosin 
C) carvedilol (Coreg) 
D) amlodipine (Norvasc) 
A) prazosin (Minipress) 
B) tamsulosin 
C) carvedilol (Coreg) 
D) amlodipine (Norvasc) C

Question 2

What is the weakest type of diuretics?

Accepted Answer

A) Carbonic anhydrase inhibitors 
B) Osmotic diuretics 
C) Potassium-sparing diuretics 
D) Loop diuretics 
A) Carbonic anhydrase inhibitors 
B) Osmotic diuretics 
C) Potassium-sparing diuretics 
D) Loop diuretics A

Question 3

An 80-year-old patient with a history of glaucoma presents with a hypertensive emergency.Which of the following drugs would be contraindicated when caring for this patient?

Accepted Answer

A) nitroprusside (Nitropress) 
B) labetalol (Trandate) 
C) nicardipine (Cardene) 
D) fenoldopam 
A) nitroprusside (Nitropress) 
B) labetalol (Trandate) 
C) nicardipine (Cardene) 
D) fenoldopam D

Question 4

The antihypertensive effects of alpha-adrenergic blockers,such as prazosin (Minipress),Hytrin (Terazosin),and doxazosin (Cardura),are due to:

Accepted Answer

A) Reduced cardiac output. 
B) Increased cardiac output. 
C) Reduced peripheral resistance. 
D) Increased peripheral resistance. 
A) Reduced cardiac output. 
B) Increased cardiac output. 
C) Reduced peripheral resistance. 
D) Increased peripheral resistance.

Question 5

Which of the following is the mechanism of action of thiazide diuretics that causes a reduction of blood pressure?

Accepted Answer

A) Activation of beta adrenoceptors on the heart,which decreases cardiac output 
B) Decrease in sodium and water retention,which decreases blood volume,thereby decreasing cardiac output 
C) Blockage of angiotensin I from converting angiotensin II 
D) Activation of alpha adrenoceptors on the heart,which decreases cardiac output 
A) Activation of beta adrenoceptors on the heart,which decreases cardiac output 
B) Decrease in sodium and water retention,which decreases blood volume,thereby decreasing cardiac output 
C) Blockage of angiotensin I from converting angiotensin II 
D) Activation of alpha adrenoceptors on the heart,which decreases cardiac output

Question 6

Although beta-adrenergic blockers are commonly used to decrease blood pressure,what effect can they have on serum lipid patterns?

Accepted Answer

A) Increase high-density lipoproteins (HDLs) 
B) Decrease HDLs 
C) Increase low-density lipoproteins (LDLs) 
D) Decrease LDLs 
A) Increase high-density lipoproteins (HDLs) 
B) Decrease HDLs 
C) Increase low-density lipoproteins (LDLs) 
D) Decrease LDLs

Question 7

A patient says she is on a high blood pressure medication but does not remember the name.She complains that the drug is causing her to suffer a skin rash and a cough.Which of the following is she most likely taking?

Accepted Answer

A) nifedipine (Procardia) 
B) captopril (Capoten) 
C) propranolol (Inderal) 
D) prazosin (Minipress) 
A) nifedipine (Procardia) 
B) captopril (Capoten) 
C) propranolol (Inderal) 
D) prazosin (Minipress)

Question 8

Which drugs can be used alone or in combination with other classes to manage hypertension but can also be used to reduce the frequency and severity of chronic,stable angina?

Accepted Answer

A) Calcium channel blockers 
B) ACEIs 
C) Angiotensin receptor blockers 
D) Alpha antagonists 
A) Calcium channel blockers 
B) ACEIs 
C) Angiotensin receptor blockers 
D) Alpha antagonists

Question 9

What is the most common side effect of thiazide diuretics?

Accepted Answer

A) Potassium depletion 
B) Decreased plasma lipids 
C) Arterial vasodilatation 
D) Constipation 
A) Potassium depletion 
B) Decreased plasma lipids 
C) Arterial vasodilatation 
D) Constipation

Question 10

Thiazide diuretics act in the distal convoluted tubule,where they block transport of which of the following?

Accepted Answer

A) Na+ 
B) Na+ and Cl- 
C) K+ 
D) Na+ and K+ 
A) Na+ 
B) Na+ and Cl- 
C) K+ 
D) Na+ and K+

Question 11

Why are calcium channel blockers effective for treatment of hypertension?

Accepted Answer

A) They generally produce no significant central nervous system side effects and may also treat diseases that coexist with hypertension,such as angina. 
B) They vary in the extent to which they affect different calcium channels. 
C) Their antihypertensive effect may be decreased by the use of NSAIDs. 
D) They have few adverse reactions. 
A) They generally produce no significant central nervous system side effects and may also treat diseases that coexist with hypertension,such as angina. 
B) They vary in the extent to which they affect different calcium channels. 
C) Their antihypertensive effect may be decreased by the use of NSAIDs. 
D) They have few adverse reactions.

Question 12

What percentage of patients has essential hypertension?

Accepted Answer

A) 60% 
B) 70% 
C) 80% 
D) 90% 
A) 60% 
B) 70% 
C) 80% 
D) 90%

Question 13

In which population are ACEIs most effective?

Accepted Answer

A) African Americans 
B) Caucasians 
C) Hispanics 
D) Asians 
A) African Americans 
B) Caucasians 
C) Hispanics 
D) Asians

Question 14

A hypertensive patient with migraines,ischemic heart disease,or congestive heart failure would benefit most from which of the following medications?

Accepted Answer

A) Diuretics 
B) ACEIs 
C) Calcium channel blockers 
D) Beta-adrenergic blockers 
A) Diuretics 
B) ACEIs 
C) Calcium channel blockers 
D) Beta-adrenergic blockers

Question 15

African-American patients with hypertension tend to respond well to which therapeutic class of medications?

Accepted Answer

A) Beta-adrenergic blockers 
B) Calcium channel blockers 
C) ACEIs 
D) Alpha blockers 
A) Beta-adrenergic blockers 
B) Calcium channel blockers 
C) ACEIs 
D) Alpha blockers

Question 16

Which drug is not an osmotic diuretic?

Accepted Answer

A) mannitol (Osmitrol) 
B) anhydrous glycerin (Osmoglyn) 
C) amiloride (Midamor) 
D) urea (Ureaphil) 
A) mannitol (Osmitrol) 
B) anhydrous glycerin (Osmoglyn) 
C) amiloride (Midamor) 
D) urea (Ureaphil)

Question 17

Which drug is not an ACEI?

Accepted Answer

A) benazepril (Lotensin) 
B) hydralazine (Apresoline) 
C) quinapril (Accupril) 
D) captopril (Capoten) 
A) benazepril (Lotensin) 
B) hydralazine (Apresoline) 
C) quinapril (Accupril) 
D) captopril (Capoten)

Question 18

What is one of the most common reasons patients demonstrate treatment failure of hypertension?

Accepted Answer

A) Drug interactions of combination therapy diminish drug benefits 
B) Compliance failure 
C) Tolerance to the drug's mechanism of action 
D) Pharmacokinetic (ADM
E) parameters are interrupted when multiple drugs are used 
A) Drug interactions of combination therapy diminish drug benefits 
B) Compliance failure 
C) Tolerance to the drug's mechanism of action 
D) Pharmacokinetic (ADM
E) parameters are interrupted when multiple drugs are used

Question 19

Which drug type is not well tolerated in elderly hypertensive patients?

Accepted Answer

A) Calcium channel blockers 
B) ACEIs 
C) Diuretics 
D) Beta-adrenergic blockers 
A) Calcium channel blockers 
B) ACEIs 
C) Diuretics 
D) Beta-adrenergic blockers

Question 20

Which drug is typically reserved for severe to malignant hypertension that is refractory to other drugs and can cause hypertrichosis?

Accepted Answer

A) hydralazine (Apresoline) 
B) minoxidil (Loniten) 
C) prazosin (Minipress) 
D) doxazosin (Cardura) 
A) hydralazine (Apresoline) 
B) minoxidil (Loniten) 
C) prazosin (Minipress) 
D) doxazosin (Cardura)

Exam 7: Drugs Used to Regulate Blood Pressure

Which drug is both an alpha- and beta-adrenoceptor-blocking agent?

What is the weakest type of diuretics?

An 80-year-old patient with a history of glaucoma presents with a hypertensive emergency.Which of the following drugs would be contraindicated when caring for this patient?

The antihypertensive effects of alpha-adrenergic blockers,such as prazosin (Minipress),Hytrin (Terazosin),and doxazosin (Cardura),are due to:

Which of the following is the mechanism of action of thiazide diuretics that causes a reduction of blood pressure?

Although beta-adrenergic blockers are commonly used to decrease blood pressure,what effect can they have on serum lipid patterns?

A patient says she is on a high blood pressure medication but does not remember the name.She complains that the drug is causing her to suffer a skin rash and a cough.Which of the following is she most likely taking?

Which drugs can be used alone or in combination with other classes to manage hypertension but can also be used to reduce the frequency and severity of chronic,stable angina?

What is the most common side effect of thiazide diuretics?

Thiazide diuretics act in the distal convoluted tubule,where they block transport of which of the following?

Why are calcium channel blockers effective for treatment of hypertension?

What percentage of patients has essential hypertension?

In which population are ACEIs most effective?

A hypertensive patient with migraines,ischemic heart disease,or congestive heart failure would benefit most from which of the following medications?

African-American patients with hypertension tend to respond well to which therapeutic class of medications?

Which drug is not an osmotic diuretic?

Which drug is not an ACEI?

What is one of the most common reasons patients demonstrate treatment failure of hypertension?

Which drug type is not well tolerated in elderly hypertensive patients?

Which drug is typically reserved for severe to malignant hypertension that is refractory to other drugs and can cause hypertrichosis?

Conscientious and Rational Prescribing in the 21st Century

An Introduction to Pharmacodynamics and Pharmacokinetics

Communicating With Patients About Medications: a Patient-Centered Approach

Drugs Used in the Treatment of Bone and Joint Disorders

Drugs Used in the Treatment of Eye and Ear Disorders

Drugs Used in the Treatment of Cardiovascular Disorders

Drugs Used in the Treatment of Hyperlipidemias

Drugs Used in the Treatment of Blood Disorders

Drugs Used in the Treatment of Pulmonary Diseases and Disorders

Drugs Used in the Treatment of Common Disorders of the Gastrointestinal System

Drugs Used to Treat Endocrine Gland Disorders

Drugs Used in the Treatment of Diabetes Mellitus

Drugs Used to Treat Common Neurological Conditions

Practical Pharmacotherapy of Drugs Used to Treat Psychiatric Disorders

Drugs Used in the Treatment of Skin Disorders

Modern Approaches to Managing Bacterial Infections

Drugs Used in the Treatment of Nonbacterial Infections

Drugs Used in the Treatment of Neoplasms

Drugs Used to Affect Womens Health

Drugs Used to Affect Mens Health

Prescribing for the Geriatric Patient

Prescribing for the Pediatric Patient

Drugs Used to Manage Pain

The Integrative Medicine Pharmacopoeia: Herbals, vitamins, and Dietary Supplements

Agents Used to Manipulate the Immune Response

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