Question 1

Which form of iron supplementation is typically used only for patients on hemodialysis?

Accepted Answer

A) Iron sucrose 
B) Iron dextran 
C) Iron polysaccharide complex 
D) Gluconate 
E) Sodium ferric 
A) Iron sucrose 
B) Iron dextran 
C) Iron polysaccharide complex 
D) Gluconate 
E) Sodium ferric A

Question 2

You are treating a patient with suspected iron deficiency anemia.Which laboratory test would you order for its accuracy in rendering this diagnosis?

Accepted Answer

A) Serum ferritin level 
B) Serum iron level 
C) Vitamin B12 level 
D) Vitamin B6 level 
A) Serum ferritin level 
B) Serum iron level 
C) Vitamin B12 level 
D) Vitamin B6 level A

Question 3

Which of the following is the most common etiology of B12 deficiency in pernicious anemia?

Accepted Answer

A) Antibody interference with absorption 
B) Patient's inability to split the R factor from B12 in foods 
C) Underproduction of B12 in the large intestine 
D) Underproduction of B12 in the liver 
E) Production of antibodies to intrinsic factor 
A) Antibody interference with absorption 
B) Patient's inability to split the R factor from B12 in foods 
C) Underproduction of B12 in the large intestine 
D) Underproduction of B12 in the liver 
E) Production of antibodies to intrinsic factor B

Question 4

The American College of Chest Physicians recommends which treatment regime for patients who have had a coronary artery bypass graft (CABG)?

Accepted Answer

A) aspirin 162 to 325 mg stat,then 75 to 100 mg daily indefinitely 
B) clopidogrel 150 mg stat,then 75 mg daily 
C) aspirin 75 to 100 mg daily if tolerated,indefinitely 
D) clopidogrel 300 mg stat,then 150 mg daily indefinitely 
E) aspirin 75 mg plus clopidogrel 75 mg daily indefinitely 
A) aspirin 162 to 325 mg stat,then 75 to 100 mg daily indefinitely 
B) clopidogrel 150 mg stat,then 75 mg daily 
C) aspirin 75 to 100 mg daily if tolerated,indefinitely 
D) clopidogrel 300 mg stat,then 150 mg daily indefinitely 
E) aspirin 75 mg plus clopidogrel 75 mg daily indefinitely

Question 5

What dose of aspirin would you recommend for a patient with a positive family history of CV disease who is taking this medication to prevent either MI or Cerebral vascular aneurism (CVA)?

Accepted Answer

A) 30 mg/day 
B) 150 mg/day 
C) 81 mg/day 
D) 101 mg/day 
E) 91 mg/day 
A) 30 mg/day 
B) 150 mg/day 
C) 81 mg/day 
D) 101 mg/day 
E) 91 mg/day

Question 6

What medical advice would you give to a patient without any cardiovascular (CV)risk factors and no other positive medical history who wants to take aspirin prophylactically to prevent future heart problems?

Accepted Answer

A) Take a loading dose of 325 mg aspirin,them 81 mg daily. 
B) Do not take aspirin because the risks outweigh the benefits. 
C) Take 81 mg daily for 1 year. 
D) Take 81 mg daily indefinitely. 
E) Take aspirin/extended release dipyridamole (Aggrenox)instead of aspirin. 
A) Take a loading dose of 325 mg aspirin,them 81 mg daily. 
B) Do not take aspirin because the risks outweigh the benefits. 
C) Take 81 mg daily for 1 year. 
D) Take 81 mg daily indefinitely. 
E) Take aspirin/extended release dipyridamole (Aggrenox)instead of aspirin.

Question 7

Which option describes the mechanism of action for warfarin?

Accepted Answer

A) Directly inhibits thrombin production 
B) Inhibits vitamin K epoxide reductase 
C) Inhibits cyclo-oxygenase (COX-1) 
D) Prevents the conversion of prothrombin to thrombin 
A) Directly inhibits thrombin production 
B) Inhibits vitamin K epoxide reductase 
C) Inhibits cyclo-oxygenase (COX-1) 
D) Prevents the conversion of prothrombin to thrombin

Question 8

A patient new to your practice has been taking dabigatran (Pradaxa).Which of the following drugs is contraindicated while taking this drug?

Accepted Answer

A) aspirin 
B) rifampin (Rifadin) 
C) ampicillin 
D) methylphenidate (Ritalin) 
E) amiodarone (Cordarone) 
A) aspirin 
B) rifampin (Rifadin) 
C) ampicillin 
D) methylphenidate (Ritalin) 
E) amiodarone (Cordarone)

Question 9

You have just completed a history on a patient newly admitted to the internal medicine service at your hospital with an admitting diagnosis of DVT,r/o PE.The patient admits to taking an antihypertensive for blood pressure and ginseng,ginger,and gingko for memory improvement.How will this information affect his discharge orders?

Accepted Answer

A) No change to antihypertensive therapy;DC ginseng only 
B) No change to antihypertensive therapy;DC gingko only 
C) No change to antihypertensive therapy;DC ginseng and gingko 
D) No change to antihypertensive therapy;DC ginseng,ginger,and gingko 
E) No change needed for any of these meds;may continue after discharge 
A) No change to antihypertensive therapy;DC ginseng only 
B) No change to antihypertensive therapy;DC gingko only 
C) No change to antihypertensive therapy;DC ginseng and gingko 
D) No change to antihypertensive therapy;DC ginseng,ginger,and gingko 
E) No change needed for any of these meds;may continue after discharge

Question 10

Which of the following is necessary for monitoring a patient on LMWH?

Accepted Answer

A) Regular International Normalized Ratio,at least monthly 
B) PTT,daily 
C) Bleeding time daily 
D) Activated clotting time 
E) None 
A) Regular International Normalized Ratio,at least monthly 
B) PTT,daily 
C) Bleeding time daily 
D) Activated clotting time 
E) None

Question 11

When monitoring a patient with vitamin B12 deficiency,which of the following labs would show the effects of supplementation first?

Accepted Answer

A) Hematocrit 
B) Reticulocyte count 
C) Folate level 
D) Iron level 
E) Ferritin level 
A) Hematocrit 
B) Reticulocyte count 
C) Folate level 
D) Iron level 
E) Ferritin level

Question 12

Fibrinolytic agents are always indicated in which of the following situations,assuming there are no patient contraindications?

Accepted Answer

A) Any patient who presents to the emergency department with chest pain. 
B) Any patient who presents with ST elevation on an electrocardiogram. 
C) Any patient with STEMI who presents within 12 hours of onset. 
D) Any patient under the age of 65 who presents with STEMI within 12 hours of onset. 
E) Any patient who presents with ST depression within 12 hours of onset. 
A) Any patient who presents to the emergency department with chest pain. 
B) Any patient who presents with ST elevation on an electrocardiogram. 
C) Any patient with STEMI who presents within 12 hours of onset. 
D) Any patient under the age of 65 who presents with STEMI within 12 hours of onset. 
E) Any patient who presents with ST depression within 12 hours of onset.

Question 13

Concomitant ingestion of iron and which vitamin will enhance the absorption of iron?

Accepted Answer

A) 500 mg vitamin C 
B) 500 mg vitamin D 
C) Vitamin B12 
D) Vitamin E 
A) 500 mg vitamin C 
B) 500 mg vitamin D 
C) Vitamin B12 
D) Vitamin E

Question 14

You are a physician assistant student on your internal medicine rotation when you are asked how you would order heparin to treat a patient with deep vein thrombosis (DVT)and possible pulmonary embolism (PE).Which response would be most appropriate?

Accepted Answer

A) Give 80 units/kg IV,then 18 units/kg/hour. 
B) Give 60 units/kg IV,then 18 units/kg/hour. 
C) Give 40 units/kg IV,then 18 units/kg/hour. 
D) Give 5,000 units SC every 8 to 12 hours. 
E) Give a bolus of 60 to 70 units/kg,then 1,000 units/hour. 
A) Give 80 units/kg IV,then 18 units/kg/hour. 
B) Give 60 units/kg IV,then 18 units/kg/hour. 
C) Give 40 units/kg IV,then 18 units/kg/hour. 
D) Give 5,000 units SC every 8 to 12 hours. 
E) Give a bolus of 60 to 70 units/kg,then 1,000 units/hour.

Question 15

Dipyridamole can be used for prevention of strokes and for which other situation?

Accepted Answer

A) Dipyridamole can be used for prevention of MI. 
B) Dipyridamole is used IV for nonexercise cardiac stress testing. 
C) Dipyridamole is primarily used in atrial fibrillation. 
D) Dipyridamole is used only to treat an acute stroke. 
A) Dipyridamole can be used for prevention of MI. 
B) Dipyridamole is used IV for nonexercise cardiac stress testing. 
C) Dipyridamole is primarily used in atrial fibrillation. 
D) Dipyridamole is used only to treat an acute stroke.

Question 16

Which test is the gold standard for diagnosing iron deficiency anemia?

Accepted Answer

A) CBC 
B) Hemoglobin level and hematocrit 
C) Serum vitamin C level 
D) Serum ferritin 
E) Bone marrow biopsy 
A) CBC 
B) Hemoglobin level and hematocrit 
C) Serum vitamin C level 
D) Serum ferritin 
E) Bone marrow biopsy

Question 17

You are caring for a patient with both cardiovascular risk of MI and a history of a GI bleed from an ulcer.What would be the most effective plan of treatment for this patient?

Accepted Answer

A) enteric-coated aspirin 81 mg daily only. 
B) aspirin 81 mg daily with clopidogrel (Plavix)75 mg daily. 
C) clopidogrel 75 mg daily only. 
D) aspirin 81 mg daily with esomeprazole (Nexium)20 mg daily. 
E) esomeprazole (Nexium)20 mg daily only. 
A) enteric-coated aspirin 81 mg daily only. 
B) aspirin 81 mg daily with clopidogrel (Plavix)75 mg daily. 
C) clopidogrel 75 mg daily only. 
D) aspirin 81 mg daily with esomeprazole (Nexium)20 mg daily. 
E) esomeprazole (Nexium)20 mg daily only.

Question 18

A patient who is on aspirin daily for prevention of cardiovascular events asks you if he can take acetaminophen for his headaches.How should you reply?

Accepted Answer

A) "Yes,you can take both drugs at the same time." 
B) "Yes,but you should take the acetaminophen 1 hour after the aspirin." 
C) "Yes,but you should cut the aspirin dose in half." 
D) "Yes,but you should cut the acetaminophen in half." 
E) "No,you cannot take both medications at the same time." 
A) "Yes,you can take both drugs at the same time." 
B) "Yes,but you should take the acetaminophen 1 hour after the aspirin." 
C) "Yes,but you should cut the aspirin dose in half." 
D) "Yes,but you should cut the acetaminophen in half." 
E) "No,you cannot take both medications at the same time."

Question 19

You are treating a patient who has been recently diagnosed with pernicious anemia.What is the preferred method of supplementation?

Accepted Answer

A) IM injections of cyanocobalamin only 
B) PO ingestion of cyanocobalamin only 
C) IV administration of cyanocobalamin only 
D) Either IM or PO administration cyanocobalamin 
A) IM injections of cyanocobalamin only 
B) PO ingestion of cyanocobalamin only 
C) IV administration of cyanocobalamin only 
D) Either IM or PO administration cyanocobalamin

Question 20

What is the primary function of platelets in hemostasis?

Accepted Answer

A) Adhere to injured blood vessels 
B) Combat infection 
C) Provide autoimmunity 
D) Adjust vessel dilatation 
A) Adhere to injured blood vessels 
B) Combat infection 
C) Provide autoimmunity 
D) Adjust vessel dilatation

Exam 9: Drugs Used in the Treatment of Blood Disorders

Which form of iron supplementation is typically used only for patients on hemodialysis?

You are treating a patient with suspected iron deficiency anemia.Which laboratory test would you order for its accuracy in rendering this diagnosis?

Which of the following is the most common etiology of B12 deficiency in pernicious anemia?

The American College of Chest Physicians recommends which treatment regime for patients who have had a coronary artery bypass graft (CABG)?

What dose of aspirin would you recommend for a patient with a positive family history of CV disease who is taking this medication to prevent either MI or Cerebral vascular aneurism (CVA)?

What medical advice would you give to a patient without any cardiovascular (CV)risk factors and no other positive medical history who wants to take aspirin prophylactically to prevent future heart problems?

Which option describes the mechanism of action for warfarin?

A patient new to your practice has been taking dabigatran (Pradaxa).Which of the following drugs is contraindicated while taking this drug?

Which of the following is necessary for monitoring a patient on LMWH?

When monitoring a patient with vitamin B12 deficiency,which of the following labs would show the effects of supplementation first?

Fibrinolytic agents are always indicated in which of the following situations,assuming there are no patient contraindications?

Concomitant ingestion of iron and which vitamin will enhance the absorption of iron?

You are a physician assistant student on your internal medicine rotation when you are asked how you would order heparin to treat a patient with deep vein thrombosis (DVT)and possible pulmonary embolism (PE).Which response would be most appropriate?

Dipyridamole can be used for prevention of strokes and for which other situation?

Which test is the gold standard for diagnosing iron deficiency anemia?

You are caring for a patient with both cardiovascular risk of MI and a history of a GI bleed from an ulcer.What would be the most effective plan of treatment for this patient?

A patient who is on aspirin daily for prevention of cardiovascular events asks you if he can take acetaminophen for his headaches.How should you reply?

You are treating a patient who has been recently diagnosed with pernicious anemia.What is the preferred method of supplementation?

What is the primary function of platelets in hemostasis?

Conscientious and Rational Prescribing in the 21st Century

An Introduction to Pharmacodynamics and Pharmacokinetics

Communicating With Patients About Medications: a Patient-Centered Approach

Drugs Used in the Treatment of Bone and Joint Disorders

Drugs Used in the Treatment of Eye and Ear Disorders

Drugs Used in the Treatment of Cardiovascular Disorders

Drugs Used to Regulate Blood Pressure

Drugs Used in the Treatment of Hyperlipidemias

Drugs Used in the Treatment of Pulmonary Diseases and Disorders

Drugs Used in the Treatment of Common Disorders of the Gastrointestinal System

Drugs Used to Treat Endocrine Gland Disorders

Drugs Used in the Treatment of Diabetes Mellitus

Drugs Used to Treat Common Neurological Conditions

Practical Pharmacotherapy of Drugs Used to Treat Psychiatric Disorders

Drugs Used in the Treatment of Skin Disorders

Modern Approaches to Managing Bacterial Infections

Drugs Used in the Treatment of Nonbacterial Infections

Drugs Used in the Treatment of Neoplasms

Drugs Used to Affect Womens Health

Drugs Used to Affect Mens Health

Prescribing for the Geriatric Patient

Prescribing for the Pediatric Patient

Drugs Used to Manage Pain

The Integrative Medicine Pharmacopoeia: Herbals, vitamins, and Dietary Supplements

Agents Used to Manipulate the Immune Response

Filters

Which of the following is the most common etiology of B₁₂ deficiency in pernicious anemia?

When monitoring a patient with vitamin B₁₂ deficiency,which of the following labs would show the effects of supplementation first?