Exam 4: Linkage, Recombination, and the Mapping of Genes on Chromosomes

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Griffith found that smooth (S)forms of S.pneumoniae have a polysaccharide capsule and rough (R)forms do not.Only S forms cause infection.Briefly describe how Griffith demonstrated transformation using live R form and heat-killed S form bacteria.

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DNA replication occurs through a _________ process.

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How did Watson and Crick's scientific approach differ from that of other scientists who studied DNA?

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DNA is localized mainly in the

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If chromosomal DNA were single stranded,which of the following would be most reduced compared to a double stranded molecule?

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The protein that progressively unwinds DNA ahead of each replication fork is called

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The step in DNA replication in which the proteins connect the correct sequence of nucleotides into a continuous new strand is called

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The ratio of _____ is 1:1.

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Why is RNA required for DNA replication?

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A region of DNA 100 bp in length has the potential to be represented by 4100 unique sequences.

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The nucleotide that is present in RNA but not DNA is

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In the Hershey and Chase experiment designed to determine the molecule of heredity,what was radiolabelled with 35S?

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If 35% of the bases in a region of the mouse genome are cytosine,what percentage in that region are adenine?

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When Meselson and Stahl performed the experiment that showed that replication is a semiconservative process,they utilized E.coli,and various isotopes of nitrogen (15N and 14N).Explain briefly what their results would have been if DNA replicated conservatively.

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Hershey and Chase relied on ________ to physically separate the infected bacterial cells from the phage ghosts.

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During early interphase,the state of the DNA can be described as

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In DNA replication,new DNA is produced in a continuous bidirectional fashion.

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Human DNA is replicated in a conservative manner.

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Prokaryotes have a circular chromosome surrounded by a nuclear membrane.

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Meselson and Stahl relied on equilibrium density gradient centrifugation in a _______ solution to resolve the DNA containing 14N from the DNA containing 15N.

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