Question 1

Which region(s) of a gene are NOT found within the mRNA transcript?

Accepted Answer

A)  promoter and termination region 
B)  promoter region 
C)  stop codon 
D)  termination region 
E)  promoter and stop codon 
A)  promoter and termination region 
B)  promoter region 
C)  stop codon 
D)  termination region 
E)  promoter and stop codon A

Question 2

The rat a- tropomyosin (a- Tm) gene produces nine different mature mRNA proteins from a single gene using which three "alternative" mechanisms?

Accepted Answer

A)  5' cap, branch points, polyadenylation 
B)  5' cap, self- splicing, polyadenylation 
C)  splicing, start codon, stop codon 
D)  promoters, start codon, poly(
A)  signal sequences 
E)  splicing, promoters, and polyadenylation 
A)  5' cap, branch points, polyadenylation 
B)  5' cap, self- splicing, polyadenylation 
C)  splicing, start codon, stop codon 
D)  promoters, start codon, poly(
A)  signal sequences 
E)  splicing, promoters, and polyadenylation E

Question 3

You want to design a drug that prevents transcription of eukaryotic mRNAs but does not affect transcription of other RNAs. What enzyme would you target?

Accepted Answer

A)  RNA polymerase III 
B)  RNA polymerase I 
C)  ribozyme 
D)  methyl transferase 
E)  RNA polymerase II 
A)  RNA polymerase III 
B)  RNA polymerase I 
C)  ribozyme 
D)  methyl transferase 
E)  RNA polymerase II E

Question 4

RNA polymerase I transcribes which tandem- repeat genes in nucleoli?

Accepted Answer

A)  mRNA 
B)  tRNA 
C)  siRNA 
D)  rRNA 
E)  all types of RNA 
A)  mRNA 
B)  tRNA 
C)  siRNA 
D)  rRNA 
E)  all types of RNA

Question 5

A cell has a defect in polyadenylation of mRNA. The RNA transcripts encoding which type of protein would NOT be affected by this defect because they are not polyadenylated?

Accepted Answer

A)  SR proteins 
B)  histone proteins 
C)  DNA binding proteins 
D)  transcription factors 
E)  transmembrane proteins 
A)  SR proteins 
B)  histone proteins 
C)  DNA binding proteins 
D)  transcription factors 
E)  transmembrane proteins

Question 6

Polyadenylation begins with the binding of _________near a six- nucleotide mRNA sequence, AAUAAA, downstream of the stop codon.

Accepted Answer

cleavage and polyade

Question 7

Which of the following statements accurately describes tRNA?

Accepted Answer

A)  tRNAs are a variety of lengths and fold into a variety of shapes. 
B)  Amino acids are bound to the 5' end of the tRNA. 
C)  Wobble in the anticodon allows a single tRNA to bind to multiple codons. 
D)  Post- transcriptional modifications of tRNAs are not necessary for their function. 
E)  All organisms produce tRNAs corresponding to the 61 amino- acid coding codons. 
A)  tRNAs are a variety of lengths and fold into a variety of shapes. 
B)  Amino acids are bound to the 5' end of the tRNA. 
C)  Wobble in the anticodon allows a single tRNA to bind to multiple codons. 
D)  Post- transcriptional modifications of tRNAs are not necessary for their function. 
E)  All organisms produce tRNAs corresponding to the 61 amino- acid coding codons.

Question 8

One type of RNA editing involves inserting uracils into edited mRNA with the assistance of which type of specialized RNA?

Accepted Answer

A)  telomerase RNA 
B)  guide RNA 
C)  post- transcriptional editor RNA 
D)  transposon RNA 
E)  small nucleolar RNA 
A)  telomerase RNA 
B)  guide RNA 
C)  post- transcriptional editor RNA 
D)  transposon RNA 
E)  small nucleolar RNA

Question 9

What is the purpose of alternative splicing in eukaryotic cells?

Accepted Answer

A)  Improve the efficiency of transcription and translation. 
B)  Regulate the quantity of any single protein being produced in the cell. 
C)  Increase the number of genes that do not have to contain introns. 
D)  Produce multiple types of tRNAs that can bind to different codons. 
E)  Produce multiple polypeptide sequences from a single primary transcript. 
A)  Improve the efficiency of transcription and translation. 
B)  Regulate the quantity of any single protein being produced in the cell. 
C)  Increase the number of genes that do not have to contain introns. 
D)  Produce multiple types of tRNAs that can bind to different codons. 
E)  Produce multiple polypeptide sequences from a single primary transcript.

Question 10

What proteins are bound to enhancers, forming a protein "bridge" that bends the DNA over the promoter to initiate transcription?

Accepted Answer

The answer of What proteins are bound to enhancers, forming...

Question 11

Processing of the 30S pre- RNA transcript in humans produces which three rRNAs after enzymatic cleavage?

Accepted Answer

The answer of Processing of the 30S pre- RNA transcript...

Question 12

Describe the mechanism(s) used by bacteria and eukaryotes for transcription termination.

Accepted Answer

Bacterial transcription termination can

Question 13

RNA polymerase is called a_______, meaning it is an intact complex with full enzymatic capacity.

Accepted Answer

The answer of RNA polymerase is called a_______, meaning it...

Question 14

Describe the three main differences between bacterial and eukaryotic mRNA transcripts.

Accepted Answer

• Eukaryotic mRNA transcripts are more s

Question 15

Which of the following is part of a DNA molecule?

Accepted Answer

A)  sigma 
B)  activator 
C)  RNA polymerase 
D)  promoter 
E)  transcription factor 
A)  sigma 
B)  activator 
C)  RNA polymerase 
D)  promoter 
E)  transcription factor

Question 16

What are two distinguishing features of RNA?

Accepted Answer

A)  RNA has a ribose sugar and uracil nitrogenous base. 
B)  RNA contains phophodiester bonds as part of its sugar backbone. 
C)  RNA forms a double helix of reverse complementary strands. 
D)  RNA contains a methylated form of thymine. 
E)  RNA contains a pyrophosphate group bound to the ribose. 
A)  RNA has a ribose sugar and uracil nitrogenous base. 
B)  RNA contains phophodiester bonds as part of its sugar backbone. 
C)  RNA forms a double helix of reverse complementary strands. 
D)  RNA contains a methylated form of thymine. 
E)  RNA contains a pyrophosphate group bound to the ribose.

Question 17

What are the mechanisms for transcription termination in bacteria?

Accepted Answer

intrinsic

Question 18

What is the - 35 consensus sequence for the following sequences?

Accepted Answer

A)  ACAA 
B)  TTGATA 
C)  TATGAT 
D)  TATTAT 
E)  TAGTAT 
A)  ACAA 
B)  TTGATA 
C)  TATGAT 
D)  TATTAT 
E)  TAGTAT

Question 19

In the following prokaryotic DNA sequence, label the highlighted regions.
  
 Using the prokaryotic DNA sequence above, describe the relationship between the highlighted regions and how mutations in each region may affect gene expression.

Accepted Answer

The - 10 (Pribnow) and - 35 consensus se

Question 20

Which three types of RNAs are found in both prokaryotes and eukaryotes?

Accepted Answer

mRNA, tRNA

Exam 8: Molecular Biology of Transcription and Rna Processing

Which region(s) of a gene are NOT found within the mRNA transcript?

The rat a- tropomyosin (a- Tm) gene produces nine different mature mRNA proteins from a single gene using which three "alternative" mechanisms?

You want to design a drug that prevents transcription of eukaryotic mRNAs but does not affect transcription of other RNAs. What enzyme would you target?

RNA polymerase I transcribes which tandem- repeat genes in nucleoli?

A cell has a defect in polyadenylation of mRNA. The RNA transcripts encoding which type of protein would NOT be affected by this defect because they are not polyadenylated?

Polyadenylation begins with the binding of _________near a six- nucleotide mRNA sequence, AAUAAA, downstream of the stop codon.

Which of the following statements accurately describes tRNA?

One type of RNA editing involves inserting uracils into edited mRNA with the assistance of which type of specialized RNA?

What is the purpose of alternative splicing in eukaryotic cells?

What proteins are bound to enhancers, forming a protein "bridge" that bends the DNA over the promoter to initiate transcription?

Processing of the 30S pre- RNA transcript in humans produces which three rRNAs after enzymatic cleavage?

Describe the mechanism(s) used by bacteria and eukaryotes for transcription termination.

RNA polymerase is called a_______, meaning it is an intact complex with full enzymatic capacity.

Describe the three main differences between bacterial and eukaryotic mRNA transcripts.

Which of the following is part of a DNA molecule?

What are two distinguishing features of RNA?

What are the mechanisms for transcription termination in bacteria?

What is the - 35 consensus sequence for the following sequences?

In the following prokaryotic DNA sequence, label the highlighted regions. Using the prokaryotic DNA sequence above, describe the relationship between the highlighted regions and how mutations in each region may affect gene expression.

Which three types of RNAs are found in both prokaryotes and eukaryotes?

The Molecular Basis of Heredity, Variation, and Evolution

Transmission Genetics

Cell Division and Chromosome Heredity

Inheritance Patterns of Single Genes and Gene Interaction

Genetic Linkage and Mapping in Eukaryotes

Genetic Analysis and Mapping in Bacteria and Bacteriophage

Dna Structure and Replication

The Molecular Biology of Translation

Chromosome Chapter Title Tbd

Gene Mutation, Dna Repair, and Homologous Recombination

Chromosome Chapter Title Tbd

Regulation of Gene Expression in Bacteria and Bacteriophage

Regulation of Gene Expression in Eukaryotes

Analysis of Gene Function by Forward Genetics and Reverse Genetics

Recombinant Dna Technology and Its Applications

Genomics: Genetics From a Whole-Genome Perspective

Organelle Inheritance and the Evolution of Organelle Genomes

Developmental Genetics

Genetic Analysis of Quantitative Traits

Population Genetics and Evolution at the Population, Species, and Molecular Levels

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