Exam 20: Genetic Analysis of Quantitative Traits

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How would you calculate the coefficient of inbreeding for individual IV- 1 in the pedigree below? How would you calculate the coefficient of inbreeding for individual IV- 1 in the pedigree below?

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D

_________is an evolutionary mechanism that favors the reproductive success of certain members of a population over others as a result of differences in anatomical, physiological, or behavioral traits they possess.

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Natural selection

In the pattern of natural selection called _________the favored phenotype has a homozygous genotype, while the consequence of natural selection favoring the heterozygote is a balanced polymorphism.

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directional natural selection or directional selection

The coefficient of inbreeding (F) can be used to estimate the proportion of loci that are_________ .

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A difference in allelic frequencies that is produced when a new population is established by a few individuals is known as what type of genetic drift?

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Which aspect of population genetics can lead to changes in allele frequencies in a new mixed population following migration?

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Researchers collect data on an island population of frogs and find a mutation rate of the recessive allele, d, is 1 × 10- 6. The relative fitness of the individuals homozygous from this allele is 0.7. What is the allele frequency of this recessive allele at equilibrium?

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All Old Order Amish families from Lancaster County with Ellis- van Creveld syndrome can trace their genealogies to Mr. and Mrs. Samuel King, who immigrated to Lancaster County in 1744. This is an example of___________ .

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What type of geographic separation resulted in diversification of an ancestral species of ground squirrel into two species, Ammospermophilus leucurus, found on the north rim of the Grand Canyon, and members of the Ammospermophilus harrisii on the south rim of the canyon?

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Of the five aspects of Hardy- Weinberg equilibrium, which one directly affects phenotypic frequencies rather than genotypic frequencies?

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The coefficient of inbreeding quantifies the probability that two alleles in a homozygous individual are ___________, having descended from the same copy of the allele carried by a common ancestor of the inbred individual.

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The incidence of Tay Sachs, an autosomal recessive genetic disorder, is approximately 1 in 3,500 in a certain population of Ashkenazi Jews. Assuming Hardy- Weinberg equilibrium, what is the frequency of carriers for the Tay Sachs allele in this population?

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If the relative fitness value is w = 0.6, what is the selection coefficient used to identify the differences between the fitnesses of organisms with different traits?

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When examining the effects of forward and reverse mutation rates, what equation is used to calculate the change in the frequency of A2, or Oq?

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Given the following genetic profile, what is the mean fitness of the population? Genotype A1A1 A1A2 A2A2 Frequency 0.55 0.20 0.25 Number 2750 1000 1250 Relative fitness (w) 1.0 0.75 0.50

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Data for an autosomal recessive trait shows that heterozygous individuals have the highest relative fitness. Those who are unaffected and homozygous for the dominant A allele have a relative fitness of 84% compared to heterozygous individuals, but only about 30% of those who are affected survived to reproduce. What is the estimated equilibrium frequency for allele A in this population?

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What is the ultimate source of genetic variation in populations?

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When populations share a single habitat but are isolated by genetic or postzygotic mechanisms that prevent gene flow, what process can cause populations to diverge?

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Which mechanism maintains the biological ability of populations to interbreed and can thus prevent evolutionary divergence of populations?

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In an insect species, survival in agricultural fields regularly sprayed with insecticide is determined by the genotype for a detoxification enzyme encoded by a gene with two alleles, A and D. Which of the following statements is consistent with the data? Genotype Relative Fitness 1.00 0.70 0.05

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